Results 231 to 240 of about 6,141,319 (295)

Synthesis of condensed chiral pyranopyran derivatives with antiproliferative activity using domino Knoevenagel-IMHDA sequences. [PDF]

RSC Adv
Király SB, Buglyó B, Ooko OM, Bényei A, Lisztes E, Tóth BI, Bíró T, Borozsnyai K, Oláh D, Vasvári G, Nemes D, Vecsernyés M, Fenyvesi F, Kurtán T.   +13 more
europepmc   +1 more source

Neointimal Hyperplasia and Restenosis: Epidemiology, Pathophysiology, Animal Models, Clinical Features, Diagnosis, and Management

MedComm, Volume 7, Issue 11, November 2026.
The overall graphical diagram to summarize the pathological characteristics, pathogenesis, clinical manifestation, preclinical animal models, diagnostic methods, and intervention strategies for neointimal hyperplasia. Neointimal hyperplasia results from excessive proliferation and intimal migration of vascular smooth muscle cells (VSMCs) in the ...
Kaixu Wang, Daiyu Zhang, Yu Hu, Yixin Zhao, Xinling Wang, Long Jiang, Meixiu Jiang   +6 more
wiley   +1 more source

Sulfonylated Goniothalamin and Piplartine Derivatives Exhibit Selective Antiproliferative Activity on Breast Cancer Cells via Oxidative Stress-Mediated Mechanisms. [PDF]

ACS Omega
Nacif JLM, Bartolomeu AA, Lamartine-Hanemann SDS, Zavan B, Nascimento LM, Caixeta ES, Aissa AF, Pilli RA, Ionta M.   +8 more
europepmc   +1 more source

Hydroxamic Acids as HDAC Inhibitor Drug Leads for Malaria

Medicinal Research Reviews, Volume 46, Issue 6, Page 1477-1498, November 2026.
ABSTRACT Malaria is a global health threat, with an estimated 282 million cases and 610,000 malaria‐associated deaths reported in 2024. Most mortality is due to infection by Plasmodium falciparum parasites, with the highest burden occurring in Sub‐Saharan Africa.
Wisam A. Dawood, Jacinta R. Macdonald, Christian Anzenhofer, Tina S. Skinner‐Adams, Robert C. Reid, Thomas Kurz, David P. Fairlie, Katherine T. Andrews   +7 more
wiley   +1 more source

Speciation of Tetracycline and Its Zn^2<b>+</b> Complexes in Aqueous Solution and Their Antiproliferative Activity in Non-Small Lung Cancer Cells. [PDF]

ACS Omega
Abate C, Carnamucio F, Foti C, Ceraj M, Cordaro M, da Rocha SRP, Giuffrè O.   +6 more
europepmc   +1 more source

Pharmacological and Therapeutic Potential of Garlic (Allium sativum): Integrating Phytochemistry, Molecular Mechanisms, and Clinical and Preclinical Evidence

ChemistryOpen, Volume 15, Issue 11, November 2026.
Garlic bioactive compounds, including organosulfur compounds (allicin, DADS, DATS, and SAC), phenolic compounds, and quercetin, regulate the Nrf2/HO‐1, NF‐κB, PI3K/Akt, and AMPK/eNOS signaling pathways. These actions enhance antioxidant defenses, suppress inflammation, improve metabolic and cardiovascular function, and contribute to reduced blood ...
Gudisa Bereda
wiley   +1 more source

Virtual screening and experimental validation of a METTL3-targeting peptide with <i>in vitro</i> antiproliferative activity against non-small cell lung cancer cells. [PDF]

J Enzyme Inhib Med Chem
Dai Y, Wu H, Shen Y, Yang F, Liu X, Zhuang T.   +5 more
europepmc   +1 more source

Cold Plasma‐Activated Liposomes as a Strategy for Controlled Metal‐Based Drug Delivery

Plasma Processes and Polymers, Volume 23, Issue 11, November 2026.
This study introduces plasma‐triggered liposomal cargo release as a promising new approach for externally activatable drug delivery systems by investigating the release of a Pt‐based anticancer drug candidate from a liposomal formulation after treatment with cold atmospheric plasma.
Fahd Afzal, Niklas Nawrath, Axel Steinbrueck, Luisa Lachnicht, Fabian Vogel Martin, Nandan Sheernaly, Frank Peeters, Andrew R. Gibson, Nils Metzler‐Nolte   +8 more
wiley   +1 more source

Characterization of Alternaria alternata alternariol monomethyl ether with a potential antiproliferative activity by topoisomerases inhibition; molecular docking and dynamic simulations. [PDF]

Sci Rep
El-Sayed ASA, Aboelez MO, Ezelarab HAA, Ewedah TM, El-Baz AF, Ashraf R, Diab A, Safwat G, Rady AM, El-Mekkawy RM.   +9 more
europepmc   +1 more source

Design, Synthesis and Biophysical Characterisation of CPP‐PNA Conjugates for Targeting Oncogenic microRNA‐221

Journal of Peptide Science, Volume 32, Issue 11, November 2026.
Cell‐penetrating peptide‐peptide nucleic acid (CPP‐PNA) conjugates that target the oncogenic microRNA‐221‐5p were synthesised using Cu(I)‐catalysed azide‐alkyne cycloaddition (CuAAC) and disulfide‐mediated conjugation strategies. These constructs form highly stable, sequence‐selective PNA/RNA heteroduplexes and demonstrate preliminary antiproliferative
Martina Rotondo, Françoise Illien, Fabienne Burlina, Barbara Biondi   +3 more
wiley   +1 more source