Results 231 to 240 of about 155,512 (310)

Saikosaponin A Inhibits Migration/Invasion and Triggers Cell‐Cycle Arrest and Autophagy‐Induced Cell Death in HCT116 Cells and In Vivo

open access: yesFood Frontiers, Volume 7, Issue 3, May 2026.
Saikosaponin A from Radix Bupleuri inhibited colorectal cancer HCT116 cells with low toxicity. SSA induced S/G2‐M cell cycle arrest and triggered autophagy via mTOR inhibition. SSA suppressed metastasis by blocking PI3K/AKT signaling pathway. SSA significantly reduced tumor growth without apparent toxicity.
Xiu‐Xiu Zhang   +7 more
wiley   +1 more source

Homoisoflavonoids—From Natural Specificity and Biosynthesis to Precision Health‐Promoting Mechanisms

open access: yesFood Frontiers, Volume 7, Issue 3, May 2026.
Homoisoflavonoids are rare flavonoids with a unique bi‐aromatic oxygen‐heterocyclic structure. This review synthesizes their structure–activity relationships in anti‐inflammatory, hypoglycemic, and anticancer contexts. By highlighting their specific natural distribution and outlining biosynthetic pathways, it provides a conceptual framework and ...
Jing Zhang   +4 more
wiley   +1 more source

Self-Assembled Cannabigerol-Based Nanoparticles: Design, Synthesis, and Antiproliferative Activity. [PDF]

open access: yesPharmaceutics
Amenta A   +13 more
europepmc   +1 more source

Comparative Effect of African Walnut Oil and Docosahexaenoic Acid on Hematological and Oxidative Stress Markers of Female Wistar Rats With 7,12‐Dimethylbenz[a]anthracene‐Induced Breast Cancer

open access: yesFood Science &Nutrition, Volume 14, Issue 5, May 2026.
African walnut oil and docosahexaenoic acid administration to female Wistar rats with DMBA‐induced breast cancer may delay tumor growth, increase white blood cells, platelets and mean corpuscular hemoglobin counts in the blood. DMBA significantly lowers red blood cells, hemoglobin levels, and protein concentration.
Fabrice Tonfack Djikeng   +3 more
wiley   +1 more source

Synthesis, Characterization, and Cytotoxic Activity Properties of Some Novel Purine Derivatives

open access: yesJournal of Biochemical and Molecular Toxicology, Volume 40, Issue 5, May 2026.
Nine novel purine derivatives were successfully synthesized and its cytotoxic activities were evaluated against HepG2 and MDA‐MB‐231 cancer cell lines. ABSTRACT This study reports the synthesis of nine new compounds with purine scaffolds. It thoroughly analyzes them using a variety of spectroscopic methods, including high‐resolution mass spectrometry ...
Nurdan Akdoğan   +6 more
wiley   +1 more source

Potential of solid‐state microwaves in lab‐scale chemical‐process development

open access: yesJournal of Chemical Technology &Biotechnology, Volume 101, Issue 5, Page 1077-1093, May 2026.
Abstract BACKGROUND The integration of a solid‐state microwave (MW) generator into a newly designed, versatile MW reactor ensures improved energy efficiency, precise process control and broader application potential. In its most particular feature, the device supports the modification of dielectric‐radiation orientation and can be operated under ...
Christian Cravotto   +4 more
wiley   +1 more source

Discovery of First-in-Class Carbonic Anhydrase/Histone Deacetylase Dual Inhibitors with Antiproliferative Activity in Cancer Cells. [PDF]

open access: yesJ Med Chem
Bozdag M   +16 more
europepmc   +1 more source

The barley–malt–beer chain: A process and food safety approach

open access: yesJSFA reports, Volume 6, Issue 5, Page 144-159, May 2026.
Abstract This review addresses the current state of knowledge on the barley–malt–beer chain and its main physical, chemical, and microbiological contaminants, with particular emphasis on spoilage microorganisms and their toxic metabolites. The barley–malt–beer production chain represents a mature and globally relevant agro‐industrial sector that ...
José Gómez‐Espinoza   +5 more
wiley   +1 more source

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