Results 261 to 270 of about 5,874,294 (289)

Antiproliferative activity of salinomycin and its derivatives

Bioorganic & Medicinal Chemistry Letters, 2012
Antiproliferative activity of seven amides and one benzotriazole ester derivative of salinomycin, a polyether ionophore antibiotic, with recently reported antibacterial activity, are herein described. Salinomycin and the majority of derivatives exhibit potent antiproliferative activity against the drug-resistant cancer cell lines.
Adam, Huczyński, Jan, Janczak, Michał, Antoszczak, Joanna, Wietrzyk, Ewa, Maj, Bogumil, Brzezinski   +5 more
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Enhancement of antiproliferative activity by phototautomerization of anthrylphenols

Photochemical & Photobiological Sciences, 2015
An antiproliferative investigation was conducted on 3 human cancer cell lines, HCT 116 (colon), MCF-7 (breast), and H 460 (lung), on a series of 4 anthrylphenols in the dark and upon exposure to light (350 nm). 9-(2-Hydroxyphenyl)anthracene (1) moderately inhibited proliferation, but irradiation considerably enhanced the effect. The other anthracenes 4–
Marijeta Kralj, Lidija Uzelac, Yu-Hsuan Wang, Peter Wan, Martina Tireli, Kata Mlinarić-Majerski, Ivo Piantanida, Nikola Basarić   +7 more
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Antiproliferative activities of tea and herbal infusions

Food & Function, 2013
The consumption of tea and herbal infusions has increased rapidly in recent years. More and more people consume these infusions as daily beverages as well as for health purposes. The aim of this study was to supply new information on the antiproliferative function of these infusions for nutritionists and the general public.
Fang, Li, Sha, Li, Hua-Bin, Li, Gui-Fang, Deng, Wen-Hua, Ling, Xiang-Rong, Xu   +5 more
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Antioxidant and Antiproliferative Activities of Common Vegetables

Journal of Agricultural and Food Chemistry, 2002
Epidemiological studies have shown that consumption of fruits and vegetables is associated with reduced risk of chronic diseases. Increased consumption of fruits and vegetables containing high levels of phytochemicals has been recommended to prevent chronic diseases related to oxidative stress in the human body. In this study, 10 common vegetables were
Yi-Fang, Chu, Jie, Sun, Xianzhong, Wu, Rui Hai, Liu   +3 more
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Synthesis and antiproliferative activity of 6-phenylaminopurines

European Journal of Medicinal Chemistry, 2014
A series of novel 6-phenylaminopurines have been efficiently synthesized in 3 steps exploring different groups at positions 2, 8 and 9 of the purine ring and at the exocyclic nitrogen atom at position 6. Among the newly described purines, five compounds showed antiproliferative activity with IC50 values below 10 μM, the tetrahydroquinoline derivative ...
María-Dolores Canela, Sandra Liekens, María-José Camarasa, Eva María Priego, María-Jesús Pérez-Pérez   +4 more
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Berberine as Source of Antiproliferative Hybrid Compounds: In Vitro Antiproliferative Activity and Quantitative Structure-activity Relationship

Anti-Cancer Agents in Medicinal Chemistry, 2019
Background:Despite advances for cancer treatment, it still remains a major worldwide public health problem. Compounds derived from natural sources are important alternatives to combat this mortal disease. Berberine is an isoquinoline alkaloid with a wide variety of pharmacological properties, including antiproliferative activity.
Mario A, Leyva-Peralta, Ramón E, Robles-Zepeda, Rodrigo S, Razo-Hernández, Laura P Á, Berber, Karen O, Lara, Eduardo, Ruiz-Bustos, Juan C, Gálvez-Ruíz   +6 more
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Antibacterial and antiproliferative activity of cationic fullerene derivatives

Bioorganic & Medicinal Chemistry Letters, 2003
AbstractFor Abstract see ChemInform Abstract in Full Text.
Tadahiko, Mashino, Dai, Nishikawa, Kyoko, Takahashi, Noriko, Usui, Takao, Yamori, Masako, Seki, Toyoshige, Endo, Masataka, Mochizuki   +7 more
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A Review on Antiproliferative and Apoptotic Activities of Natural Honey

Anti-Cancer Agents in Medicinal Chemistry, 2014
Recent statistics revealed that cancer is one among the main reasons for death throughout the world. Several treatments are available but still there is no cure when it is detected at late stages. One of the treatment modes for cancer is chemotherapy which utilizes anticancer drugs in order to eradicate the cancer cells by apoptosis.
Jaganathan, Saravana Kumar, Balaji, Arunpandian, Vellayappan, Muthu Vignesh, Asokan, Manjesh Kumar, Subramanian, Aruna Priyadharshni, John, Agnes Aruna, Supriyanto, Eko, Razak, Saiful Izwan Abd, Marvibaigi, Mohsen   +8 more
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Synthesis and Antiproliferative Activity of Thioazolidine Analogues for Melanoma.

ChemInform, 2007
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Wei, Li, Yan, Lu, Zhao, Wang, James T, Dalton, Duane D, Miller   +4 more
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Effects of Hypoxia on the Antiproliferative Activity of Human Interferons

Journal of Interferon & Cytokine Research, 1995
We studied the effects of pharmacologically attainable concentrations of interferon-alpha (IFN-alpha) and gamma (IFN-gamma) on the growth of cells incubated under hypoxic conditions (2% O2; approximately 14 mm Hg partial pressure) or exposed to oxygen at atmospheric pressure (21% O2; approximately 147 mm Hg).
NALDINI, A., CARRARO, F., BOCCI, V.
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