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Synthesis and use of polyamine derivatives as internal mass spectrometry standards [PDF]

Dar, Sami Ullah
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Synthesis and antiproliferative activity of retroetoposide

Bioorganic & Medicinal Chemistry Letters, 2003
Retro-4'-demethyl-4-epipodophyllotoxin 6 was synthesized in eight steps and 10% overall yield from 4'-demethyl-4-epipodophyllotoxin 12. Subsequent coupling of 22 with 1-O-trimethylsilyl-4,6-O-ethylidene-beta-D-glucoside 26 afforded retroetoposide 5 which is 10-fold less cytotoxic than etoposide against L1210 cell line.
Philippe, Meresse, Prokopios, Magiatis, Emmanuel, Bertounesque, Claude, Monneret   +3 more
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Antioxidant and Antiproliferative Activities of Raspberries

Journal of Agricultural and Food Chemistry, 2002
Raspberries are rich in phenolic phytochemicals. To study the health benefits of raspberries, four fresh raspberry varieties (Heritage, Kiwigold, Goldie, and Anne) were evaluated for total antioxidant and antiproliferative activities. The total amount of phenolics and flavonoids for each of the four raspberry varieties was determined.
Ming, Liu, Xin Qi, Li, Courtney, Weber, Chang Yong, Lee, Janice, Brown, Rui Hai, Liu   +5 more
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Antiproliferative Activity of Cobra Venom Cytotoxins

Current Topics in Medicinal Chemistry, 2015
Cytotoxins (or cardiotoxins, CTs) are small rigid membrane-active proteins of the three-finger toxin (TFT) family. They comprise about 60 amino acid residues, stabilized by four disulphide bridges. CTs, the most abundant proteins in cobra venom are able to kill cancer cells in a dose and time-dependent manner.
Peter V, Dubovskii, Yuri N, Utkin
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Antioxidant and Antiproliferative Activities of Strawberries

Journal of Agricultural and Food Chemistry, 2003
Strawberries contain high levels of antioxidants, which have been correlated with a decreased risk of chronic disease. To more fully characterize the antioxidant profiles and possible associated health benefits of this fruit, the total free and bound phenolic, total flavonoid, and total anthocyanin contents of eight strawberry cultivars (Earliglow ...
Katherine J, Meyers, Christopher B, Watkins, Marvin P, Pritts, Rui Hai, Liu   +3 more
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Synthesis and antiproliferative activity of alkylphosphocholines

Chemistry and Physics of Lipids, 2003
Alkylphosphocholines (APC) with one or more methylene groups in the alkyl chain replaced by oxygen atoms or carbonyl groups, or both have been assembled modularly using omega-diols as central building blocks. Out of 25 new compounds of this kind, 11 were evaluated for their antiproliferative activity on four cell lines and compared with miltefosine to ...
M. AGRESTA, D'ARRIGO, PAOLA, FASOLI, EZIO, D. LOSI, G. PEDROCCHI FANTONI, S. RIVA, SERVI, STEFANO, TESSARO, DAVIDE   +7 more
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Antiproliferative and Cytotoxic Activities

2018
Cancer is a genetic disease, affecting many people worldwide. Chemotherapy is routinely used for cancer treatment. However, this therapeutic approach is not always effective due to the development of cell resistance and toxic effects. Plants are a reservoir of natural chemicals with chemoprotective potential against cancer and with low adverse effects.
Anesini, Claudia Alejandra, Alonso, Maria del Rosario, Martino, Renzo Fabricio   +2 more
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