Results 81 to 90 of about 2,581 (172)

In vitro and in vivo antitrypanosomal activity of the fresh leaves of Ranunculus Multifidus Forsk and its major compound anemonin against Trypanosoma congolense field isolate

BMC Veterinary Research
Background Animal trypanosomiasis is a major livestock problem due to its socioeconomic impacts in tropical countries. Currently used trypanocides are toxic, expensive, and the parasites have developed resistance to the existing drugs, which calls for an
Betelhem Sirak, Gizachew Kassahun Bizuneh, Peter Imming, Kaleab Asres   +3 more
doaj   +1 more source

Research Approaches for the Discovery of Trypanocidal Molecular Prototypes from Plants

Natural Product Communications
In the absence of vaccines, chemotherapy remains a viable alternative for the control of African trypanosomiasis. To facilitate the eradication of African trypanosomiasis, there is the need to pay attention to the chemotherapeutic potential of secondary ...
Aboagye Kwarteng Dofuor
doaj   +1 more source

Antitrypanosomal activity of Tithonia Diversifolia

, 2016
The African Trypanosomiases, also commonly called African sleeping sickness in humans (HAT) and “Nagana” in domestic livestock, are fatal neglected diseases that occur in 36 sub-Saharan African countries. The disease progresses through two stages and is caused by two subspecies of the parasite T. brucei: T. b. gambiense (West Africa; Tbg) and T.
Dall’Acqua, Stefano, Sut, Stefania, Baldan, Valeria, PETRELLI, Riccardo, Ranjbarian, Farah, Hofer, Anders, CAPPELLACCI, Loredana, MAGGI, Filippo   +7 more
openaire   +1 more source

Antimicrobial and antitrypanosomal activities of methanol root extract and fractions of Brenania brieyi (De Wild) Petit (Rubiaceae)

African Journal of Pharmaceutical Research and Development (AJOPRED)
Brenania brieyi (Rubiaceae) is used in ethnomedicine for the treatment of malaria, microbial infections, trypanosomal disease, infertility and inflammatory disorders.
Ifeyinwa Chioma Ezeala, Philip Felix Uzor, Charity Ukamaka Obiora, Chidimma Maryann Enendu, Chidozie Innocent Anyadiegwu, Ngozi Justina Nwodo   +5 more
doaj  

Harnessing nature: a systematic exploration of <i>in vitro</i> antileishmanial and antihuman African trypanosomal properties in traditional medicinal plants and their active principles. [PDF]

Pharm Biol
Ahmed QU, Mat Nasir NA, Begum T, Helal Uddin ABM, Parveen H, Albalawi MO, Ali Khan Khattak MM, Azmi SNH, Sarian MN, Kurniawati AD, Zakaria ZA.   +10 more
europepmc   +1 more source

5‑Nitrofuran-Semicarbazone Hybrids as Antitrypanosomal Agents: Structure-Activity Relationship and Nitroreductase Activation. [PDF]

ACS Med Chem Lett
Alegbejo Price TO, Silva DG, Vaidergorn MM, Augusto BS, Matheeussen A, Van Pelt N, Caljon G, Riley J, Read KD, Medina-Franco JL, Nonato MC, Emery FS.   +11 more
europepmc   +1 more source

Evaluation of NTD-O2, a Ghanaian herbal medicine, for onchocerciasis and animal African trypanosomiasis. [PDF]

BMC Complement Med Ther
Anibea BZ, Coffie E, Ayine-Tora DM, Gwira TM, Osei-Safo D.   +4 more
europepmc   +1 more source

Synthesis and Antitrypanosomal Activity of Novel 2‑Nitroimidazole-3,5-Disubstituted Isoxazole Derivatives with Diaryl Ether and Thioether Substituents. [PDF]

ACS Omega
Santos LBB, Carvalho DB, Shiguemoto CYK, Lacerda OD, Silva TS, Portapilla GB, Silva-Filho SE, Guerrero PG, de Albuquerque S, Baroni ACM.   +9 more
europepmc   +1 more source

RNA Polymerase 1 inhibitors against African trypanosomes <i>in vitro</i> and in mice. [PDF]

Antimicrob Agents Chemother
Cumming AV, Nenortas NP, Nenortas E, Bakshi RP, Caton ER, Rios-Guzman E, Barry ME, Barrow JC, Laiho M, Shapiro TA.   +9 more
europepmc   +1 more source

Chagas Disease: An Opportunistic Infection in AIDS. [PDF]

Curr Infect Dis Rep
Popovic K, Henao-Martínez AF, Ngo LQ, Botero AH, Agudelo Higuita NI.   +4 more
europepmc   +1 more source