Results 81 to 90 of about 35,652 (265)

Atypical clinical and imaging manifestation in neurocysticercosis

Annals of Indian Academy of Neurology, 2011
A 20-year-old man presented with left-sided headache and seizures of three years duration. Conglomerate ring-enhancing lesions were seen in the first magnetic resonance imaging study. He was initially treated with anticonvulsants for two years.
L Dayananda, C Kesavadas, Bejoy Thomas, R Neelima, V V Radhakrishnan   +4 more
doaj   +1 more source

Spectrum of Functional Abdominal Pain Disorders in Children and Their Clinical, Social Characteristics: A Cross‐Sectional Study

JGH Open, Volume 9, Issue 4, April 2025.
ABSTRACT Background/Aims Pediatric functional abdominal pain disorders (FAPDs) subtypes; functional dyspepsia (FD), irritable bowel syndrome (IBS), functional abdominal pain‐not otherwise specified (FAP‐NOS), and abdominal migraine (AM) are influenced by demographic and social factors. The study aimed to evaluate the spectrum and demographic and social
Jayendra Seetharaman, Ujjal Poddar, Anshu Srivastava, Moinak Sen Sarma, Surender Kumar Yachha   +4 more
wiley   +1 more source

T3P‐Promoted Synthesis of a Series of Novel 3‐Aryl‐2‐phenyl‐2,3,5,6‐tetrahydro‐4H ‐1,3‐thiazin‐4‐ones

Journal of Heterocyclic Chemistry, Volume 62, Issue 4, Page 338-344, April 2025.
A series of 12 novel 3‐aryl‐2‐phenyl‐2,3,5,6‐tetrahydro‐4H‐1,3‐thiazin‐4‐ones was prepared at room temperature by T3P‐mediated cyclization of C‐phenyl‐N‐aryl imines with 3‐mercaptopropionic acid. Both electron‐withdrawing and electron‐donating substituents were used. All substituents were successful, including p‐nitro.
Lee J. Silverberg, Tapas Mal, Anthony Lagalante, Mark Olsen, Michael Fleming, Tracy Garcia, Aloura Gavalis, Kyanna Gonzalez, Casey Gregory, Laine Hackenberg, Madeline Lawler, Eddie Li, Evelyn Louca, Shaheem Mack, Kristen Perhonitch, Kelsey Shaffer, Carter Thompson, Sarah Tran, Evan Vidal, Ryan Vidal   +19 more
wiley   +1 more source

Efficient computational model for identification of antitubercular peptides by integrating amino acid patterns and properties

FEBS Letters, 2019
Tuberculosis (TB) is a leading killer caused by Mycobacterium tuberculosis. Recently, anti‐TB peptides have provided an alternative approach to combat antibiotic tolerance.
Shamima Khatun, M. Hasan, H. Kurata
semanticscholar   +1 more source

Synthesis, and biological screening of chloropyrazine conjugated benzothiazepine derivatives as potential antimicrobial, antitubercular and cytotoxic agents

Arabian Journal of Chemistry, 2021
A series of twenty new chloropyrazine conjugated benzothiazepines (22–41) have been synthesized with 58%–95% yields. The compounds were characterized by using different spectroscopic techniques including FT-IR, 1H NMR, 13C NMR spectroscopy and mass ...
Afzal B. Shaik, Richie R. Bhandare, Srinath Nissankararao, Bontha Venkata Subrahmanya Lokesh, Shaik Shahanaaz, M. Mukhlesur Rahman   +5 more
doaj  

Non linear Prediction of Antitubercular Activity Of Oxazolines and Oxazoles derivatives Making Use of Compact TS-Fuzzy models Through Clustering with orthogonal least sqaure technique and Fuzzy identification system [PDF]

arXiv, 2014
The prediction of uncertain and predictive nonlinear systems is an important and challenging problem. Fuzzy logic models are often a good choice to describe such systems however in many cases these become complex soon. commonlly, too less effort is put into descriptor selection and in the creation of suitable local rules.
arxiv  

Antitubercular potential and pH‐driven mode of action of salicylic acid derivatives

FEBS Open Bio, Volume 15, Issue 3, Page 383-398, March 2025.
Salicylic acid (SA), its two iodinated analogues 5ISA and 3,5diISA, as well as the anti‐inflammatory drug aspirin (ASP), are anti‐TB drugs that disrupt the intrabacterial pH homeostasis of Mycobacterium tuberculosis under in vitro conditions mimicking the endolysosomal pH of macrophages.
Janïs Laudouze, Thomas Francis, Emma Forest, Frédérique Mies, Jean‐Michel Bolla, Céline Crauste, Stéphane Canaan, Vadim Shlyonsky, Pierre Santucci, Jean‐François Cavalier   +9 more
wiley   +1 more source

Dual Burden of MDR‐TB and COVID‐19 in a Previously Treated Tuberculosis Case: Diagnostic and Therapeutic Dilemmas

Clinical Case Reports, Volume 13, Issue 3, March 2025.
ABSTRACT The presence of both MDR‐TB and COVID‐19 complicates diagnosis and treatment, as their symptoms can overlap, resulting in possible delays in receiving the appropriate care. This study aimed to investigate whether COVID‐19 plays a role in the initiation or progression of latent or current tuberculosis (TB) infection, especially MDR‐TB, through ...
Gudisa Bereda
wiley   +1 more source

Flavin‐Dependent Nitroreductases: Privileged Enzymes for Chemical and Photochemical Synthesis

ChemCatChem, Volume 17, Issue 5, March 6, 2025.
This review summarizes the functional, structural, and mechanistic properties of flavin‐dependent nitroreductases and highlights their usefulness for the synthesis of nitrogen‐containing compounds. Recent advances in enzyme and cofactor engineering, as well as in the use of nitroreductases in photobiocatalytic approaches, are emphasized.
Sara Russo, Alejandro Prats Luján, Marco W. Fraaije, Gerrit J. Poelarends   +3 more
wiley   +1 more source

Design, synthesis, antitubercular and antiviral properties of new spirocyclic indole derivatives

Chemical Monthly, 2019
A series of indole-based spirothiazolidinones have been designed, synthesized and evaluated, in vitro, for their antitubercular, antiviral, antibacterial, and antifungal activities.
Gökçe Cihan-Üstündağ, L. Naesens, Dilek Şatana, Gonca Erköse-Genç, Emel Mataracı-Kara, G. Çapan   +5 more
semanticscholar   +1 more source