Results 11 to 20 of about 3,707,085 (259)

Dataset of 2-(2-(4-aryloxybenzylidene) hydrazinyl) benzothiazole derivatives for GQSAR of antitubercular agents [PDF]

Data in Brief, 2017
Fragment based Quantitative structure activity relationship (QSAR) analysis on reported 25 2-(2-(4-aryloxybenzylidene) hydrazinyl) benzothiazole dataset as antitubercular agents were carried out.
Amit S. Tapkir, Sohan S. Chitlange, Ritesh P. Bhole   +2 more
doaj   +2 more sources

The recent advances in benzimidazole-based antimicrobials and antitubercular agents

Future Journal of Pharmaceutical Sciences
Background Benzimidazole, a fused heterocyclic compound, has emerged as a privileged structure in medicinal chemistry due to its broad spectrum of biological activities, particularly in antimicrobial and antitubercular (anti-TB) applications.
Abdalrahman Tarek, Maiy Y. Jaballah, Eman Z. Elrazaz, Nermin Samir   +3 more
doaj   +2 more sources

Phytogenic silver, gold, and bimetallic nanoparticles as novel antitubercular agents [PDF]

International Journal of Nanomedicine, 2016
Richa Singh,1 Laxman Nawale,2 Manisha Arkile,2 Sweety Wadhwani,1 Utkarsha Shedbalkar,1 Snehal Chopade,1 Dhiman Sarkar,2 Balu Ananda Chopade1,3 1Department of Microbiology, Savitribai Phule Pune University, 2Combichem-Bioresource Center, Organic ...
Singh R, Nawale L, Arkile M, Wadhwani S, Shedbalkar U, Chopade S, Sarkar D, Chopade BA   +7 more
doaj   +2 more sources

Tetrahydropyrazolo[1,5-a]Pyrimidine-3-Carboxamide and N-Benzyl-6′,7′-Dihydrospiro[Piperidine-4,4′-Thieno[3,2-c]Pyran] analogues with bactericidal efficacy against Mycobacterium tuberculosis targeting MmpL3 [PDF]

, 2013
Mycobacterium tuberculosis is a major human pathogen and the causative agent for the pulmonary disease, tuberculosis (TB). Current treatment programs to combat TB are under threat due to the emergence of multi-drug and extensively-drug resistant TB.
A Hill, A Koul, AE Grzegorzewicz, Alfonso Mendoza-Losana, Anil Kumar Tyagi, C Dye, C Varela, Carlos Alemparte, Carolina González, Chrystala Constantinidou, CK Stover, David Barros, David J. Dow, DJ Payne, Douglas J. Minick, Elena Jiménez, Esther Pérez-Herrán, Fátima Ortega-Muro, Gurdyal S. Besra, Iñigo Angulo-Barturen, JA Maddry, Joaquín Rullás, Johnson Afari, Jorge Esquivias, K Andries, K Pethe, K Tahlan, LL Ballell, Lluís Ballell, M Berry, M Biava, M Murray, M Protopopova, Mark J. Pallen, María José Rebollo-López, María Martínez-Hoyos, María Teresa Fraile-Gabaldón, Modesto J. Remuiñán, Mónica Cacho, Nalini Mehta, Nicholas Cammack, Nicholas J. Loman, R Singh, SA Stanley, ST Cole, V La Rosa, V Makarov, Verónica Sousa, Vickey L. Spivey   +48 more
core   +22 more sources

Causality assessment, severity and preventability of adverse drug reactions due to first-line antitubercular agents [PDF]

Pharmaciana, 2022
TB (Tuberculosis) is a common infectious disease affecting humans since very long time. Multidrug therapy with its associated adverse drug reactions is one of the major concerns for the management of TB.
Gunjan Upadhyay, Apexa B Shukla, Darshan J Dave   +2 more
doaj   +1 more source

Microbial glycosylation of antitubercular agent chlorflavonin [PDF]

Journal of Bioscience and Bioengineering, 2023
Flavonoids have shown health-benefiting properties, such as antioxidative and anti-inflammatory activities, and are commonly used as nutraceuticals and pharmaceuticals. Although flavonoids are predominantly identified from plants, several filamentous fungal species have also been reported to produce bioactive flavonoids, including chlorflavonin from ...
Jie Ren, Jixun Zhan
openaire   +3 more sources

QSAR modeling, molecular docking, dynamic simulation and ADMET study of novel tetrahydronaphthalene derivatives as potent antitubercular agents

Beni-Suef University Journal of Basic and Applied Sciences, 2023
Tuberculosis is an air-borne contagious disease caused by slow-growing Mycobacterium tuberculosis (Mtb). According to Global Tuberculosis Report 2022, 1.6 million people were infected by tuberculosis in 2021.
Anguraj Moulishankar, T. Sundarrajan
semanticscholar   +1 more source

Inhalable spray-dried chondroitin sulphate microparticles: effect of different solvents on particle properties and drug activity [PDF]

, 2020
Spray-drying stands as one of the most used techniques to produce inhalable microparticles, but several parameters from both the process and the used materials affect the properties of the resulting microparticles.
Buttini, Francesca, da Costa, Ana M Rosa, Faleiro, Maria Leonor, Flórez Fernández, Noelia, Grenha, Ana, Rodrigues, Susana, Torres, María Dolores   +6 more
core   +1 more source

Synthesis of functionalized sulfonamides as antitubercular agents

Phosphorus Sulfur and Silicon and the Related Elements, 2023
Using up-to-date methods for synthesis and analysis, 51 sulfonamides were prepared for use as tools in antitubercular drug discovery. The synthetic efforts were centered on varying substituents at three key structural units implicated in antimicrobial ...
M. Hearn, Catherine D. Pugh, M. Cynamon
semanticscholar   +1 more source

Sputum Smear Non-conversion at the End of Intensive Phase of Tuberculosis Treatment at a Tertiary Center: A Descriptive Cross-sectional study

Journal of Nepal Medical Association, 2021
Introduction: Sputum non-conversion is smear positive tuberculosis despite anti-tubercular therapy. Various factors may lead to sputum non-conversion including resistance to anti-tubercular drugs, age, gender, disease severity, non-compliance, drugs ...
Naveen Prakash Shah, Anil Regmi, Aakash Acharya, Jwala K.C. , Bidur Khatiwada, Meera Hada   +5 more
doaj   +1 more source