Results 1 to 10 of about 6,574 (207)

Immune response to snake envenoming and treatment with antivenom; complement activation, cytokine production and mast cell degranulation. [PDF]

PLoS Neglected Tropical Diseases, 2013
BACKGROUND: Snake bite is one of the most neglected public health issues in poor rural communities worldwide. In addition to the clinical effects of envenoming, treatment with antivenom frequently causes serious adverse reactions, including ...
Shelley F Stone, Geoffrey K Isbister, Seyed Shahmy, Fahim Mohamed, Chandana Abeysinghe, Harendra Karunathilake, Ariaranee Ariaratnam, Tamara E Jacoby-Alner, Claire L Cotterell, Simon G A Brown   +9 more
doaj   +3 more sources

Presentation and management of snakebite envenomation at a District Hospital in the north-east of South Africa [PDF]

African Journal of Emergency Medicine
Background: Snakebites have been recognised as a neglected tropical disease by the World Health Organization and remain a potentially preventable cause of morbidity around the world, particularly in Africa.
Matamba Jean Benoit Kabeya, Darryl Wood, Peter Hodkinson   +2 more
doaj   +2 more sources

Low-dose adrenaline, promethazine, and hydrocortisone in the prevention of acute adverse reactions to antivenom following snakebite: a randomised, double-blind, placebo-controlled trial.

PLoS Medicine, 2011
BackgroundEnvenoming from snakebites is most effectively treated by antivenom. However, the antivenom available in South Asian countries commonly causes acute allergic reactions, anaphylactic reactions being particularly serious.
H Asita de Silva, Arunasalam Pathmeswaran, Channa D Ranasinha, Shaluka Jayamanne, Senarath B Samarakoon, Ariyasena Hittharage, Ranjith Kalupahana, G Asoka Ratnatilaka, Wimalasiri Uluwatthage, Jeffrey K Aronson, Jane M Armitage, David G Lalloo, H Janaka de Silva   +12 more
doaj   +2 more sources

Antivenom Administration After Rattlesnake Envenoming in Arizona Does Not Directly Diminish Pain [PDF]

Toxins
The onset, progression, and severity of pain following rattlesnake envenomation are highly variable between patients. Pain can be severe and persistent, seemingly refractory to opioid analgesics.
Vance G. Nielsen, Darien L. Stratton, Tyler M. Hoelscher, Hannah L. Nakamura, Matthew M. Cornelison, William F. Rushton, Geoffrey T. Smelski   +6 more
doaj   +2 more sources

Cross-Reactivity and Neutralization Capacity of Polyspecific Antivenom Produced by Razi Institute against Three Species of Buthidea Family Scorpions [PDF]

Asia Pacific Journal of Medical Toxicology, 2019
Background: Scorpion sting is a significant health problem in southern provinces of Iran. Many thousands of people are stung by different species of scorpions annually. More than 60 scorpion species have been reported to be present in Iran. However, Razi
Bahzad Masihipour, Abbas Zare Mirakabadi, mehdi kheirollahpour, Hadi Rabiei, Ali Hedayat   +4 more
doaj   +1 more source

Indian Polyvalent Antivenom Accelerates Recovery From Venom-Induced Consumption Coagulopathy (VICC) in Sri Lankan Russell’s Viper (Daboia russelii) Envenoming

Frontiers in Medicine, 2022
BackgroundVenom-induced consumption coagulopathy (VICC) is an important clinical consequence of Russell’s viper (Daboia russelii) envenoming. There is limited evidence for antivenom effectiveness in resolving VICC.
Anjana Silva, Anjana Silva, Anjana Silva, Fiona E. Scorgie, Lisa F. Lincz, Kalana Maduwage, Sisira Siribaddana, Geoffrey K. Isbister, Geoffrey K. Isbister   +8 more
doaj   +1 more source

First Case Report of an Unusual Echis genus (Squamata: Ophidia: Viperidae) Body Pattern Design in Iran [PDF]

Archives of Razi Institute, 2019
Three families of venomous snakes exist in Iran including Viperidae, Elapidae, and Hydrophidae. Viperidae family is the only family with a widespread distribution. Saw-scaled vipers are important poisonous snakes in Asia and Africa. This name is given to
S. Navidpour, A. Salemi, A. Zare Mirakabadi   +2 more
doaj   +1 more source

Evaluating Antivenom Efficacy against Echis carinatus Venoms—Screening for In Vitro Alternatives

Toxins, 2022
In India, polyvalent antivenom is the mainstay treatment for snakebite envenoming. Due to batch-to-batch variation in antivenom production, manufacturers have to estimate its efficacy at each stage of IgG purification using the median effective dose ...
Siddharth Bhatia, Avni Blotra, Karthikeyan Vasudevan   +2 more
doaj   +1 more source

Cytotoxic Effect of Bee (A. mellifera) Venom on Cancer Cell Lines

Journal of Pharmacopuncture, 2020
Objectives: Nowadays cancer treatment is an important challenge in the medical world that needs better therapies. Many active secretions produced by insects such as honey bees used to discover new anticancer drugs.
Sima Khalilifard Borojeni, Hossein Zolfagharian, Mahdi Babaie, Iraj Javadi   +3 more
doaj   +1 more source

Experimental Bothrops atrox envenomation: Efficacy of antivenom therapy and the combination of Bothrops antivenom with dexamethasone. [PDF]

PLoS Neglected Tropical Diseases, 2017
Bothrops atrox snakes are the leading cause of snake bites in Northern Brazil. The venom of this snake is not included in the antigen pool used to obtain the Bothrops antivenom. There are discrepancies in reports on the effectiveness of this antivenom to
Gabriella Neves Leal Santos Barreto, Sâmella Silva de Oliveira, Isabelle Valle Dos Anjos, Hipocrates de Menezes Chalkidis, Rosa Helena Veras Mourão, Ana Maria Moura-da-Silva, Ida Sigueko Sano-Martins, Luis Roberto de Camargo Gonçalves   +7 more
doaj   +1 more source