Biomedicines, 2020 The Chinese Cobra (Naja atra) is an elapid snake of major medical importance in southern China. We describe the in vitro neurotoxic, myotoxic, and cytotoxic effects of N.
Qing Liang +4 more
doaj +1 more source
A synthetic biology approach for consistent production of plant-made recombinant polyclonal antibodies against snake venom toxins [PDF]
, 2018 Antivenoms developed from the plasma of hyperimmunized animals are the only effective treatment available against snakebite envenomation but shortage of supply contributes to the high morbidity and mortality toll of this tropical disease.
Arnold +38 more
core +2 more sources
Pharmacodynamics and pharmacokinetics of snake antivenom
Sri Lanka Journal of Medicine, 2018 Intact or fractionated immunoglobulins are used as snake antivenom to treat snake envenomation. Intravenously administered antivenom binds with snake toxins in the circulation and neutralizes the toxins.
Bhagya Nikapitiya, Kalana Maduwage
doaj +1 more source
Preclinical evaluation of caprylic acid-fractionated IgG antivenom for the treatment of Taipan (Oxyuranus scutellatus) envenoming in Papua New Guinea. [PDF]
PLoS Neglected Tropical Diseases, 2011 Snake bite is a common medical emergency in Papua New Guinea (PNG). The taipan, Oxyuranus scutellatus, inflicts a large number of bites that, in the absence of antivenom therapy, result in high mortality.
Mariángela Vargas +12 more
doaj +1 more source
Journal of Tropical Medicine, 2023 Snakebite is a global public health concern, which often occurs in tropical and subtropical underdeveloped areas, but it is often neglected. In the southern China, Naja naja atra (Chinese cobra) is a common venomous snake that causes swelling and ...
Jie Yang +10 more
doaj +1 more source
Histopathological analysis and in situ localisation of Australian tiger snake venom in two clinically envenomed domestic animals [PDF]
, 2011 Objective: To assess histopathological changes in clinically envenomed tiger snake patients and identify tissue specific localisation of venom toxins using immunohistochemistry.
Balmer, L. +5 more
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Adverse Reactions after Administration of Antivenom in Korea
Toxins, 2020 Kovax® antivenom is the main treatment for toxins produced by the Gloydius species. However, research on adverse reactions after Kovax® antivenom administration is scarce.
Jin Seok Shim +4 more
doaj +1 more source
Consequences of neglect: analysis of the sub-Saharan African snake antivenom market and the global context. [PDF]
PLoS Neglected Tropical Diseases, 2012 BACKGROUND: The worldwide neglect of immunotherapeutic products for the treatment of snakebite has resulted in a critical paucity of effective, safe and affordable therapy in many Third World countries, particularly in Africa.
Nicholas I Brown
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Current treatment for venom-induced consumption coagulopathy resulting from snakebite. [PDF]
PLoS Neglected Tropical Diseases, 2014 Venomous snakebite is considered the single most important cause of human injury from venomous animals worldwide. Coagulopathy is one of the commonest important systemic clinical syndromes and can be complicated by serious and life-threatening ...
Kalana Maduwage, Geoffrey K Isbister
doaj +1 more source
The management of a blood donor bitten by a snake [PDF]
, 2017 The worldwide burden of snakebite is high and venomous snakes are found in many regions of the world and are a threat to public health. In Italy, for instance, viper bites are an infrequent but not negligible event.
Catalano, Liviana +5 more
core +1 more source