Results 31 to 40 of about 4,705 (157)

Protein design and RNA design: Perspectives

Quantitative Biology, Volume 14, Issue 2, June 2026.
Abstract Advances in deep learning and generative modeling have transformed the landscape of protein and RNA design, enabling rapid and precise creation of novel biomolecules with tailored structures and functions. In protein design, generative deep learning frameworks now support backbone generation, sequence optimization, and joint sequence–structure
Xi Chen, Xu Dai, Peilong Lu
wiley   +1 more source

Identification of antigenic proteins from the venom of Malaysian snakes using immunoprecipitation assay and tandem mass spectrometry (LC-MS/MS)

Heliyon
Snake envenomation poses a significant risk to Malaysians and country visitors. Malaysia witnesses an estimated 650 snake bites per 100,000 population annually.
Preetha Rajendiran, Rakesh Naidu, Iekhsan Othman, Syafiq Asnawi Zainal Abidin   +3 more
doaj   +1 more source

Antivenoms for Snakebite Envenomings

Inflammation & Allergy - Drug Targets, 2011
Animal-derived antivenoms constitute the mainstay in the therapy of snakebite envenoming. Antivenoms are manufactured by immunizing animals, usually horses, with venoms from a single or several medically-relevant snake species. Antivenoms are constituted by either whole IgG molecules or the immunoglobulin fragments F(ab')₂ and Fab, obtained by ...
Gutiérrez, José María, León Montero, Guillermo, Lomonte, Bruno, Angulo Ugalde, Yamileth   +3 more
openaire   +4 more sources

Repositioning Global Health: Decolonising Narratives and Practice in the African Context

Public Health Challenges, Volume 5, Issue 1, March 2026.
ABSTRACT Background Global health practice in Africa remains shaped by enduring colonial legacies that privilege external expertise and undervalue indigenous knowledge systems. Despite widespread recognition of inequities in authorship, funding and representation, global health discourse often overlooks the deeper epistemic and cultural dimensions of ...
Michael Sarfo, Ruth Owusuaa
wiley   +1 more source

Allergic reactions to antivenom in a patient bitten twice by the same snake within a month: A rare case report and literature review

Chinese Journal of Traumatology, 2017
Antivenom is the most effective method currently available for the treatment of poisonous snake bite. Allergic reactions to antivenom have been reported in the past.
Fan-Jie Zeng, Cong Chen, Ming-Hua Liu
doaj   +1 more source

The Snake Study: Survey of National Attitudes and Knowledge in Envenomation

Toxins, 2021
Despite recent reviews of best practice for the treatment of Australian venomous bites and stings, there is controversy about some aspects of care, particularly the use of antivenom.
George Braitberg, Vasilios Nimorakiotakis, Celene Y.L. Yap, Violet Mukaro, Ronelle Welton, Anna Parker, Jonathan Knott, David Story   +7 more
doaj   +1 more source

Global Emergency Medicine: A Scoping Review of the Literature From 2024

Academic Emergency Medicine, Volume 33, Issue 3, March 2026.
ABSTRACT Objective The Global Emergency Medicine Literature Review (GEMLR) identifies impactful research in global emergency care. This 20th annual edition reviews GEM literature published in 2024 and highlights the growth of GEMLR over the years. Methods We conducted a scoping review of 2024 GEM articles through structured PubMed and gray literature ...
J. Austin Lee, Nana Serwaa A. Quao, Amanda Collier, Chris A. Rees, Morgan C. Broccoli, Nanaba A. Dawson‐Amoah, Vinay N. Kampalath, Joseph Ciano, Ashley Jacobson, Jennifer Jones, Joseph Leanza, Branden Skarpiak, Jonathan M. Strong, Braden J. Hexom, Global Emergency Medicine Literature Review (GEMLR) Group, Abdirahman Abdulle, Halley J. Alberts, Kimonia Bih Awanchiri, Emily Bartlett, Tal Berkowitz, Nidhi Bhaskar, Corey B. Bills, Joseph Bonney, Morgan C. Broccoli, Agatha Brzezinski, Whitney K. Bryant, Jonathan Chan, Joseph D. Ciano, Cassandra Clay, Ly Cloessner, Amanda Collier, Nanaba A. Dawson‐Amoah, Kamoga Dickson, Jonathan W. Dyal, Christian Engelen, Brandon Friedman, Stephanie Chow Garbern, Juliette Gerardo, Mindi Guptill, Reid Haflich, Alison S. Hayward, Braden J. Hexom, Taylor S. Hickey, Anneka Hooft, Emmanuel Oluyinka Idowu, Ashley A. Jacobson, Aqeel Jawahir, Jennifer E. Jones, Vinay N. Kampalath, Elizabeth M. Keating, Sean M. Kivlehan, Arthi S. Kozhumam, Colleen E. Laurence, Joseph Leanza, Samuel Lewis, J. Austin Lee, Gideon Loevinsohn, Parker Maddox, Mallika Manyapu, Michael Mathelier, Kevin J. Mercer, Rmaah Memon, Kevin Molyneux, Dana Naamani, Benjamin D. Nicholson, Hannah Ofosua Owusu, Gerard M. O’Reilly, Mayur Patel, Nana Serwaa Agyeman Quao, Sarah Rapaport, Chris A. Rees, Charlotte Roy, Megan M. Rybarczyk, Jessica Schmidt, Megan L. Schultz, Anand Selvam, Erin F. Shufflebarger, Yusra Shakil, Branden Skarpiak, Cheyenne Smith, Jonathan M. Strong, Janet Jebichii Sugut, Fadhila Tekka, W. Tyler Winders, Ann Wolski, Natalie Yabalwashi   +85 more
wiley   +1 more source

Tackling High Dimensionality in QSP: Guiding Model Order Reduction With Index Analysis

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 2, February 2026.
ABSTRACT Quantitative systems pharmacology (QSP) models offer a useful platform to integrate drug pharmacology with knowledge about biological mechanisms across multiple scales and data sources into a unified quantitative framework. This makes them invaluable to address many relevant questions in drug research and development.
Johannes Tillil, Wilhelm Huisinga, Jane Knöchel   +2 more
wiley   +1 more source

The anti-tumor efficacy of nanoparticulate form of ICD-85 versus free form

Archives of Razi Institute, 2015
Biodegradable polymeric nanoparticles (NPs) have been intensively studied as a possible way to enhance anti-tumor efficacy while reducing side effects. ICD-85, derived from the venom of two separate species of venomous animals, has been shown to exhibit ...
Zare Mirakabadi, A., Moradhaseli, S.,, Sarzaem, A., Soheily, S., Morovati, H.   +4 more
doaj  

Spatial Accessibility Analysis of Snake Antivenom

International Journal of Public Health
ObjectivesTo analyze the spatial accessibility of antivenom immunizing agents equipped hospitals in Hainan Province.MethodsThis paper analyzes the spatial accessibility of medical institutions equipped with different types of snake antivenom using ...
Wenjie Hao, Lanfen He, Xingyue Song, Juntao Wang, Yanlan Hu, Yu Chen, Chuanzhu Lv, Shijiao Yan   +7 more
doaj   +1 more source