TFAP2A promotes NSCLC malignant progression by enhancing AOC1 transcription [PDF]
HereditasBackground Non-small cell lung cancer (NSCLC) has high mortality, and patients show variable outcomes and drug responses. Amine oxidase copper-containing 1 (AOC1) is considered an oncogene in many types of tumors. Transcription factor AP-2 alpha (TFAP2A)
Chang Jing
exaly +5 more sources
Integrated single-cell and transcriptome sequencing data reveal the value of AOC1 in gliomas tumor microenvironment and prognosis [PDF]
BMC CancerBackground Glioma is a primary brain tumor that is frequently encountered in humans, with malignant gliomas representing an exceptionally aggressive subtype.
Jun Liu +6 more
exaly +5 more sources
METTL14 contributes to the progression of nasopharyngeal carcinoma through regulating the stability of AOC1 mRNA [PDF]
HereditasBackground Nasopharyngeal carcinoma (NPC) is a malignant epithelial tumor of the nasopharyngeal mucosa with a high incidence rate all over the world. Methyltransferase-like 14 (METTL14) is a major RNA N6-adenosine methyltransferase implicated in tumor ...
Xiwen Zhu, Xue Zhen
exaly +6 more sources
Increased AOC1 Expression Promotes Cancer Progression in Colorectal Cancer [PDF]
Frontiers in Oncology, 2021 BackgroundAmine oxidase copper containing 1 (AOC1) is a gene whose biological function in colorectal cancer (CRC) has not been elucidated. Therefore, the purpose of this study was to investigate the clinical significance of AOC1 expression in CRC and its
Peng Du, Zhehui Zhu, Weimin Xu
exaly +5 more sources
Cell Death and Disease, 2022 Amine oxidase copper-containing 1 (AOC1) is considered an oncogene in many types of tumors. Nevertheless, there have been no investigations of AOC1 and its regulatory mechanism in prostate cancer.
Jinjian Yang +2 more
exaly +4 more sources
Frontiers in Genetics, 2023 Introduction: The amine oxidase copper-containing 1 (AOC1) gene encodes for the diamine oxidase (DAO) enzyme. DAO is an enzyme that catabolizes some molecules, including histamine, and is the degradative enzyme in the polyamine catabolic pathway that is ...
Adriana Duelo
exaly +5 more sources
Identification and Validation of Tryptophan Metabolism–Related Genes in Diabetic Kidney Disease and Construction of a Clinical Prediction Model [PDF]
Journal of Diabetes ResearchConclusion: Our study suggests that the AOC1, HAAO, and STAT1 genes may be potential diagnostic biomarkers of tubular injury in DKD. OGDHL and TDO2 may be potential diagnostic biomarkers of glomerular injury in DKD. The model constructed using AOC1, HAAO,
Shaojie Liu +6 more
doaj +3 more sources
Photodynamic Therapy of Novel Photosensitizer Ameliorates TNBS-Induced Ulcerative Colitis via Inhibition of AOC1 [PDF]
Frontiers in Pharmacology, 2021 Ulcerative colitis (UC), a chronic, nonspecific inflammatory bowel disease characterized by continuous and diffuse inflammatory changes in the colonic mucosa, requires novel treatment method.
Tianjun Liu, Zhu Na, Liu Tianjun
exaly +5 more sources
Low expression and significance of AOC1 in prostate adenocarcinoma [PDF]
Translational Andrology and UrologyCurrently, amine oxidase copper-containing 1 (AOC1) is less studied in cancer. There are few studies on the relationship between AOC1 and prognosis in prostate cancer. This study explores the expression profile of AOC1 in normal prostate tissue and prostate cancer, and investigates the relationship between the expression of AOC1 and prognosis of ...
Wang HQ +12 more
exaly +4 more sources
Effect of diamine oxidase (DAO) enzyme dietary supplementation in subjects with insomnia symptoms and single nucleotide polymorphisms of the AOC1 gene: a randomized double-blind placebo-controlled study [PDF]
Sleep Medicine: XObjective: This exploratory study was designed to assess the effect of a diamine oxidase (DAO) enzyme supplement on insomnia symptoms in patients with alterations of the AOC1 gene, which encodes the DAO enzyme.
Júlia Ferrer-Garcia +6 more
doaj +4 more sources