Results 11 to 20 of about 2,098 (114)

AOC1 Contributes to Tumor Progression by Promoting the AKT and EMT Pathways in Gastric Cancer

Cancer Management and Research, 2020
Fen Xu,1,2 Yun Xu,3 Jian-Hui Xiong,4 Jing-Hui Zhang,2 Jian Wu,2 Jie Luo,2 Jian-Ping Xiong1 1The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, People’s Republic of China; 2Jiangxi Medical College, Shangrao, Jiangxi, People ...
Xu F, Xu Y, Xiong JH, Zhang JH, Wu J, Luo J, Xiong JP   +6 more
doaj   +5 more sources

Protective Effect of EGCG on Hydrogen Peroxide-induced Apoptosis of Human Cardiomyocyte via Regulating miR-16-5p/AOC1 Axis

Shipin gongye ke-ji, 2022
Objective: To explore the molecular mechanism driving the tea polyphenol epigallocatechin-3-gallate (EGCG)-exerted protective effect on hydrogen peroxide (H2O2)-induced cell apoptosis of human cardiomyocyte HCM cell lines.
Yingxin BI, Xianjun LIU, Xianglong MENG, Yue LIU, Mengyuan WANG, Yan ZHANG, Zhandong LI, Yuhe YIN, Hao LI   +8 more
doaj   +2 more sources

Excessive DAO inhibits myoblast migration, leading to impaired myotube fusion and muscle strength decline by reducing ECM [PDF]

Frontiers in Bioengineering and Biotechnology
IntroductionThe molecular mechanisms underlying muscle strength decline, particularly in age-related conditions such as sarcopenia, remain poorly understood.
Xiang Liu, Jianchao Xue, Yiming Liang, Zhenggang Li, Rui Xu, Rui Xu, Huaimei Yang, Yu Zhao, Qiyang Wang, Jianhong Hou, Sheng Lu   +10 more
doaj   +2 more sources

<i>miR444b.2</i>-HsfA1-<i>AOC1</i> module mediates heat priming-enhanced blast resistance in rice. [PDF]

Proc Natl Acad Sci U S A
As global climate change exacerbates extreme heat events, the interplay between heat stress and blast disease resistance in rice remains poorly understood. In this study, through integrated transcriptome profiling and systematic phenotyping of mutants in several thermosensory pathways, we identified HsfA1 as a positive regulator of
Qiu J, Cao X, Shi H, Chen Z, Zhang X, Cao Z, Huang D, Wen H, Chen Y, Kou Y.   +9 more
europepmc   +3 more sources

GbWRKY11 Enhances Verticillium Wilt Resistance Through Activating Jasmonic Acid Biosynthesis in Cotton. [PDF]

Mol Plant Pathol
When Verticillium dahliae invasion is recognised by cell membrane‐localised pattern recognition receptors, cotton immune signals are transduced to the nucleus, where GbWRKY11 binds to the GbLOX5 promoter and promotes the GbLOX5 transcription, thereby activating the jasmonic acid pathway and enhancing Verticillium wilt resistance.
Chen J, Yue H, Pei H, Feng G, Wang N, Ai N, Zhou B.   +6 more
europepmc   +2 more sources

Research on the potential mechanisms and therapeutic drug for the co-occurrence of major depressive disorder in castration-resistant prostate cancer [PDF]

Scientific Reports
Depression in patients with prostate cancer (PC) has become a significant public health issue. Given the high treatment failure rate and short life expectancy of patients with castration-resistant prostate cancer (CRPC), their risk of developing major ...
Lei Xu, Mingqiang Zhang, Menghua Shi, Xuyao Lin, Guozheng Qin, Wei Fu, Bin Huang   +6 more
doaj   +2 more sources

The tree of life of copper-containing amine oxidases [PDF]

Frontiers in Plant Science
Copper-containing amine oxidases (CuAOs) catalyze the terminal oxidation of polyamines (PAs), producing ammonium, an aminoaldehyde, and hydrogen peroxide (H2O2). Plant CuAOs are induced by stress-related hormones such as methyl-jasmonate (MeJA), abscisic
Zaibao Zhang, Tao Xiong, Kejia Li, Kexin Huang, Siyu Wu, Luhui Wu   +5 more
doaj   +2 more sources

Amine Oxidase Copper-containing 1 (AOC1) Is a Downstream Target Gene of the Wilms Tumor Protein, WT1, during Kidney Development [PDF]

Journal of Biological Chemistry, 2014
Amine oxidase copper-containing 1 (AOC1; formerly known as amiloride-binding protein 1) is a secreted glycoprotein that catalyzes the degradation of putrescine and histamine. Polyamines and their diamine precursor putrescine are ubiquitous to all organisms and fulfill pivotal functions in cell growth and proliferation. Despite the importance of AOC1 in
Holger Scholz, Karin Kirschner
exaly   +3 more sources

Integrated Urinary and Tissue Proteomic Signatures Reveal Core and Progression Biomarkers in MRI-Visible and MRI-Non-Visible Prostate Cancer [PDF]

Life
Background: Prostate cancer (PCa) shows a marked biological heterogeneity that is closely associated with tumor aggressiveness. A substantial proportion of clinically significant tumors remain undetected by multiparametric magnetic resonance imaging ...
Ana Blanca, Ana C. Morillo, Antonio Lopez-Beltran, Guillermo Lendinez Cano, Rafael A. Medina, Laura Chamorro Castillo, Daniel López Ruiz, Eduardo Chicano-Galvez, Juan Pablo Campos Hernández, Enrique Gómez Gómez   +9 more
doaj   +2 more sources

m6A-enriched lncRNA LINC00839 promotes tumor progression by enhancing TAF15-mediated transcription of amine oxidase AOC1 in nasopharyngeal carcinoma

Journal of Biological Chemistry, 2023
Dysregulation of long noncoding RNAs (lncRNAs) contributes to tumorigenesis by modulating specific cancer-related pathways, but the roles of N6-methyladenosine (m6A)-enriched lncRNAs and underlying mechanisms remain elusive in nasopharyngeal carcinoma (NPC). Here, we reanalyzed the previous genome-wide analysis of lncRNA profiles in 18 pairs of NPC and
Denghui Wei, Xiao-Hong Hong, Ye-Lin Liang   +2 more
exaly   +3 more sources