The Prevalence of Single Nucleotide Polymorphisms of the <i>AOC1</i> Gene Associated with Diamine Oxidase (DAO) Enzyme Deficiency in Healthy Newborns: A Prospective Population-Based Cohort Study. [PDF]
Genes (Basel)A prospective population-based study was conducted in a sample of 200 healthy newborns aimed to determine the prevalence of diamine oxidase (DAO) enzyme deficiency caused by single nucleotide polymorphisms (SNPs) variants of the AOC1 gene. Genotyping was performed in oral mucosa samples collected around 2 days after birth.
Fortes Marin E +4 more
europepmc +3 more sources
[Functional study of amine oxidase copper-containing 1 (AOC1) in lipid metabolism]. [PDF]
Sheng Wu Yi Xue Gong Cheng Xue Za ZhiAmine oxidase copper-containing 1 (AOC1) is a key member of copper amine oxidase family, which is responsible for deamination oxidation of histamine and putrescine. In recent years, AOC1 has been reported to be associated with various cancers, with its expression levels significantly elevated in certain cancer cells, suggesting its potential role in ...
Xiang S, Liu S, Li K, Zhao T, Wang X.
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Âkutskij Medicinskij žurnal, 2020 The significance of polymorphic variants of amino oxidase AOC1 and histamine-N-methyltransferase HNMT genes, involved in histamine metabolism, with predicting the risk of developing bronchial asthma (BA) in children living in the Republic of Bashkortostan was evaluated.
E K Khusnutdinova
exaly +2 more sources
Extrachromosomal DNA drives molecular and clinical heterogeneity in hepatocellular carcinoma: a multi-omics analysis and prognostic model development [PDF]
Human GenomicsBackground Extrachromosomal DNA (ecDNA) is an emerging hallmark of cancer that promotes tumor evolution and heterogeneity. However, the molecular characteristics and clinical significance of ecDNA in hepatocellular carcinoma (HCC) remain incompletely ...
Kai Huang +9 more
doaj +2 more sources
Transcriptomics and metabolomics insights into the seasonal dynamics of meat quality in yak on the Qinghai-Tibetan Plateau [PDF]
BMC GenomicsBackground Meat quality in yak is influenced by the fluctuation of nutritional composition in different grazing seasons on the Qinghai-Tibetan Plateau. However, the molecular mechanism underlying in yak meat remains unknown.
Tongqing Guo +9 more
doaj +2 more sources
Correction for Qiu et al., <i>miR444b.2</i>-HsfA1-<i>AOC1</i> module mediates heat priming-enhanced blast resistance in rice. [PDF]
Proc Natl Acad Sci U S Aeuropepmc +3 more sources
Prevalence of Genetic Diamine Oxidase (DAO) Deficiency in Female Patients with Fibromyalgia in Spain
Biomedicines, 2023 Diamine oxidase (DAO) is an enzyme that metabolizes intestinal histamine. Single nucleotide polymorphisms (SNPs) of the Amine Oxidase Copper Containing 1 (AOC1) gene can lead to low enzymatic activity or functionality in histamine metabolism.
Gülşah Okutan +8 more
doaj +1 more source
Ultrasound and microbubble-mediated delivery of miR-424-5p has a therapeutic effect in preeclampsia
Biological Procedures Online, 2023 Objective To determine the influence of ultrasound/microbubble-mediated miR-424-5p delivery on trophoblast cells and the underlying mechanism. Methods Blood pressure and 24-h proteinuria of patients with preeclampsia (PE) were measured as well as the ...
Xudong Wang +6 more
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Current Issues in Molecular Biology, 2023 Background: Cuproptosis induction is seen as a promising alternative for immunotherapies and targeted therapies in breast cancer. The objective of this research was to examine the prognostic and biological importance of cuproptosis-related genes (CRGs ...
Tingting Liu, Jianshe Wei
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