Results 51 to 60 of about 6,599 (204)
Apamin modulates ventricular repolarization in end-stage human HF.
, 2014 A. Representative action potential recorded at 1 Hz from an end-stage human HF ventricular myocyte before and after apamin. B.
Ingrid M. Bonilla (474103) +14 more
core +1 more source
The effect of Xenin25 on spontaneous circular muscle contractions of rat distal colon in vitro
Physiological Reports, 2021 Xenin25 has a variety of physiological functions in the Gastrointestinal (GI) tract, including ion transport and motility. However, the motility responses in the colon induced by Xenin25 remain poorly understood.
Yuko Kuwahara +4 more
doaj +1 more source
Triggered Calcium Lightning Programs Cochlear Development
Exploration, Volume 6, Issue 5, October 2026.Summary: Before the onset of hearing, the developing inner ear generates spontaneous calcium signals that are thought to guide maturation. In this study, we discovered a rapid and widespread calcium flash—dubbed “Ca2+ lightning”—originating from supporting cells beneath the sensory hair cells, which triggers coordinated calcium waves across the entire ...
Qiang Ma +13 more
wiley +1 more source
British Journal of Pharmacology, Volume 183, Issue 19, Page 5832-5853, October 2026.Serotonin differentially modulates layer 5 mPFC microcircuits through cell type‐specific pre‐ and postsynaptic receptor pathways. Presynaptic 5‐HT1BRs suppress glutamate and GABA release, whereas presynaptic and postsynaptic 5‐HT3ARs enhance fast‐spiking interneuron activity, whilst distinct pyramidal neuron subtypes exhibit divergent 5‐HT1AR‐ and 5 ...
Ramya Rama +4 more
wiley +1 more source
, 2013 Background: Apamin-sensitive K currents (I(KAS)) are upregulated in heart failure. We hypothesize that apamin can flatten action potential duration restitution (APDR) curve and can reduce ventricular fibrillation duration in failing ventricles.
Chen, Zhenhui +9 more
core +1 more source
Effects of Selenocysteine Substitution on the Cyclotide Kalata B2
ChemBioChem, Volume 27, Issue 18, 28 September 2026.Selenocysteine (Sec) substitution of any of the native complementary cysteine (Cys) residues of the cyclotide kalata B2 preserves the structure, cytotoxicity, and membrane‐binding activity while enhancing its folding efficiency. The study shows the conservative nature and folding benefit of selenocysteine replacement in kalata B2.
Ramoncito Luis B. de Boda +5 more
wiley +1 more source
Modulating fear extinction memory by manipulating SK potassium channels in the infralimbic cortex
Frontiers in Behavioral Neuroscience, 2014 Fear extinction correlates with increased infralimbic (IL) neuronal excitability. Since small conductance Ca2+-dependent K+ (SK) channels modulate neuronal excitability and certain types of learning and memory, pharmacological modulation of SK channels ...
Marangelie eCriado-Marrero +2 more
doaj +1 more source
Food Biomacromolecules, Volume 3, Issue 3, Page 620-645, September 2026.This review synthesizes 94 studies (2000–2025) exploring edible insects as sustainable sources of peptides, lipids, and chitin. Utilizing “green” extraction, these bioactives offer antioxidant and antimicrobial benefits for functional foods. However, addressing safety concerns like allergenicity and heavy metals through standardized frameworks remains ...
Blessing Rachael Adeyeye +1 more
wiley +1 more source
Metaplastic effect of apamin on LTP and paired-pulse facilitation
, 2007 peer reviewedIn area CA1 of hippocampal slices, a single 1-sec train of 100-Hz stimulation generally triggers a short-lasting long-term potentiation (S-LTP) of 1-2 h. Here, we found that when such a train was applied 45 min after application of the small
Capron, B. +9 more
core +1 more source
An evaluation of the chemical content and microbiological contamination of Anatolian bee venom.
PLoS ONE, 2021 Bee venom is a natural substance produced by worker bees. The aim of this research paper is to determine the characteristics of Anatolian bee venom by evaluating its chemical content and microbiological properties.
Aslı Elif Tanuğur-Samanc +1 more
doaj +1 more source