Results 51 to 60 of about 5,766 (207)

Cells and ionic conductances contributing to spontaneous activity in bladder and urethral smooth muscle

The Journal of Physiology, Volume 604, Issue 9, Page 3611-3632, 1 May 2026.
Abstract figure legend Cells and conductances contributing to spontaneous activity in the lower urinary tract. Bladder and urethra exhibit spontaneous contractions at both cellular and tissue levels. Both detrusor and urethral smooth muscle cells display activity that is regular and rhythmic.
Bernard T. Drumm, Neha Gupta, Alexandru Mircea, Caoimhin S. Griffin   +3 more
wiley   +1 more source

Apamin modulates ventricular repolarization in end-stage human HF.

, 2014
A. Representative action potential recorded at 1 Hz from an end-stage human HF ventricular myocyte before and after apamin. B.
Ingrid M. Bonilla (474103), Paulus M. L. Janssen (637703), Qing Lou (637699), Victor P. Long III (637696), Kent Mowrey (637700), Ahmet Kilic (637704), Sandor Györke (5652649), Patrick Wright (470353), Jae Yoo (637701), Cynthia A. Carnes (338043), Peter J. Mohler (35301), Vadim V. Fedorov (637702), Pedro Vargas-Pinto (637697), Andriy Belevych (637698), Philip F. Binkley (288111)   +14 more
core   +1 more source

Modulating fear extinction memory by manipulating SK potassium channels in the infralimbic cortex

Frontiers in Behavioral Neuroscience, 2014
Fear extinction correlates with increased infralimbic (IL) neuronal excitability. Since small conductance Ca2+-dependent K+ (SK) channels modulate neuronal excitability and certain types of learning and memory, pharmacological modulation of SK channels ...
Marangelie eCriado-Marrero, Edwin eSantini, James T. Porter   +2 more
doaj   +1 more source

Venom composition and pain-causing toxins of the Australian great carpenter bee Xylocopa aruana

Scientific Reports, 2022
Most species of bee are capable of delivering a defensive sting which is often painful. A solitary lifestyle is the ancestral state of bees and most extant species are solitary, but information on bee venoms comes predominantly from studies on eusocial ...
Naiqi Shi, Tibor G. Szanto, Jia He, Christina I. Schroeder, Andrew A. Walker, Jennifer R. Deuis, Irina Vetter, György Panyi, Glenn F. King, Samuel D. Robinson   +9 more
doaj   +1 more source

Compensatory Interplay Between Clarin‐1 and Clarin‐2 Deafness‐Associated Proteins Governs Phenotypic Variability in Hearing

Advanced Science, Volume 13, Issue 20, 9 April 2026.
Functional compensation between clarin‐1 and clarin‐2 in cochlear hair cells. Hearing loss associated with CLRN1 mutations shows striking phenotypic variability; however, the underlying mechanisms remain poorly understood. This study reveals that clarin‐1 and clarin‐2 function cooperatively in cochlear hair cells to sustain mechanoelectrical ...
Maureen Wentling, Aïda Yakhlef Sanchez, Nicolas Thelen, Müge Senarisoy, Maria Hogg, Steven Condamine, Andrea Lelli, Emilia Wysocka, Pranav Patni, Sandrine Vitry, Kerem Yasin Yildizhan, Sébastien Le Gal, Sylvie Nouaille, Michael R. Bowl, Marc Thiry, Didier Dulon, Sedigheh Delmaghani, Aziz El‐Amraoui   +17 more
wiley   +1 more source

Distinct Host Gene Expression Patterns Induced by Covert Deformed Wing Virus Infections in Honeybees (Apis mellifera)

Archives of Insect Biochemistry and Physiology, Volume 121, Issue 4, April 2026.
A transcriptome study was established in Ordu, Türkiye using genetically related A. mellifera anatoliaca colonies founded by super‐sister queens. Nurse bees were collected and high‐quality RNA was sequenced on an Illumina NovaSeq 6000 platform, and analyzed on the Sabancı University HPC cluster (1).
Ali Sinan Kara, Samet Okuyan, Hatice Nur Kaynak, Serap Sakarya, Zeynep Ebrar Yavuz, Salim Aktürk, Gökhan Akdeniz, Aydin Turkec, Stuart J. Lucas   +8 more
wiley   +1 more source

Apamin-sensitive SK channels are responsible for the main effect of NO on membrane potential.

, 2013
A: Representative recording of a B19 neuron before and after treatment with apamin (5 µM). Note that apamin application led to a sustained depolarization.
Stephen Estes (484038), Vincent Rehder (484040), Lei Ray Zhong (484037), Liana Artinian (484039)   +3 more
core   +1 more source

Therapeutic Potential and Mechanisms of Bee Venom Therapy: A Comprehensive Review of Apitoxin Applications and Safety Enhancement Strategies

Pharmaceuticals
Apitoxin therapy (BVT—bee venom therapy) is an emerging complementary treatment utilizing bee venom for various medical conditions. This review explores the potential and therapeutic mechanisms of bee venom, focusing on its chemical composition and the ...
Maksymilian Stela, Natalia Cichon, Aleksandra Spławska, Monika Szyposzynska, Michal Bijak   +4 more
doaj   +1 more source

Health Effects of Bee Products: A Comprehensive Review

Food Science &Nutrition, Volume 14, Issue 2, February 2026.
Nutritional composition of bee products and some health effects. ABSTRACT Honey, bee pollen, propolis, bee bread, royal jelly, bee venom, beeswax, and apilarnil are among the bee‐derived products that may serve health‐related purposes, as they exhibit various biological activities such as antibacterial, antiviral, antifungal, antioxidant, anti ...
Nevin Sanlier, Elif Yildiz Kaya, Ikbal Irem Yucel   +2 more
wiley   +1 more source

SK Current, Expressed During the Development and Regeneration of Chick Hair Cells, Contributes to the Patterning of Spontaneous Action Potentials

Frontiers in Cellular Neuroscience, 2022
Chick hair cells display calcium (Ca2+)-sensitive spontaneous action potentials during development and regeneration. The role of this activity is unclear but thought to be involved in establishing proper synaptic connections and tonotopic maps, both of ...
Snezana Levic, Snezana Levic, Snezana Levic   +2 more
doaj   +1 more source