Results 111 to 120 of about 7,237 (173)

Mechanistic insights into the versatile stoichiometry and biased signaling of the apelin receptor-arrestin complex. [PDF]

Nat Commun
Yue Y, Xu C, Wu L, Na M, Xu K, Chen X, Song Y, Weng S, Xu L, Li F, Lin X, Wang A, Liu J, Xu F.   +13 more
europepmc   +1 more source

In Vitro and In Vivo Evaluation of a Small-Molecule APJ (Apelin Receptor) Agonist, BMS-986224, as a Potential Treatment for Heart Failure. [PDF]

Circ Heart Fail, 2021
Gargalovic P, Wong P, Onorato J, Finlay H, Wang T, Yan M, Crain E, St-Onge S, Héroux M, Bouvier M, Xu C, Chen XQ, Generaux C, Lawrence M, Wexler R, Gordon D.   +15 more
europepmc   +1 more source

Structural insights into the regulation of monomeric and dimeric apelin receptor. [PDF]

Nat Commun
Yue Y, Liu L, Wu L, Xu C, Na M, Liu S, Liu Y, Li F, Liu J, Shi S, Lei H, Zhao M, Yang T, Ji W, Wang A, Hanson MA, Stevens RC, Liu J, Xu F.   +18 more
europepmc   +1 more source

Relationship Between Serum Apelin-13 and Apelin Receptor Levels and the Severity of Disease in Patients Diagnosed with Obstructive Sleep Apnea Syndrome. [PDF]

Diagnostics (Basel)
Aygun D, Erten N, Hos UD, Ibas M, Misirlioglu NF, Uzun H.   +5 more
europepmc   +1 more source

Identification of potent pyrazole based APELIN receptor (APJ) agonists. [PDF]

Bioorg Med Chem, 2020
Narayanan S, Vasukuttan V, Rajagopal S, Maitra R, Runyon SP.   +4 more
europepmc   +1 more source

The future of G protein-coupled receptor therapeutics: Apelin receptor acts as a prototype for the advancement of precision drug design. [PDF]

Clin Transl Med
Wang WW, Ji SY, Xu P, Zhang Y, Zhang Y.
europepmc   +1 more source

Harnessing the power of structure-based design: A new lease on life for cardiovascular drug development with apelin receptor modulators. [PDF]

Clin Transl Med
Zhang J, Dong E, Zhang Y, Zhang Y.
europepmc   +1 more source

L-carnitine improves metabolic disorders and regulates apelin and apelin receptor genes expression in adipose tissue in diabetic rats. [PDF]

Physiol Rep, 2020
Ranjbar Kohan N, Tabandeh MR, Nazifi S, Soleimani Z.   +3 more
europepmc   +1 more source

Blocking Palmitoylation of Apelin Receptor Alleviates Morphine Tolerance in Neuropathic Cancer Pain. [PDF]

Int J Biol Sci
Fan X, Gong M, Zhang S, Niu W, Sun S, Yu H, Chen X, Fang Z.   +7 more
europepmc   +1 more source

Increased apelin receptor gene expression in the subfornical organ of spontaneously hypertensive rats. [PDF]

PLoS One, 2020
Griffiths PR, Lolait SJ, Bijabhai A, O'Carroll-Lolait A, Paton JFR, O'Carroll AM.   +5 more
europepmc   +1 more source