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Fibrin Hydrogels to Deliver Dental Stem Cells Of the Apical Papilla for Regenerative Medicine
Regenerative Medicine, 2015Evaluation of survival, proliferation and neurodifferentiation of dental stem cells from the apical papilla (SCAP) in fibrin hydrogels. We hypothesized that fibrin composition will influence cell behavior.Modulus, pore and fiber size were measured. SCAP in vitro viability, proliferation and neural differentiation, as well as in vivo proliferation and ...
Germain, Loïc +10 more
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Role of CPNE1 in Odontoblastic Differentiation of Rat Stem Cells from Apical Papilla
Advanced Biology, 2023AbstractCPNE1 is a calcium‐dependent, phospholipid‐binding protein that is ubiquitously expressed in various tissues and organs. This study investigates the expression and localization of CPNE1 in tooth germ development and the role of CPNE1 in odontoblastic differentiation.
Xi Lu +5 more
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Journal of Endodontics, 2022
Many mediators are produced during pulp inflammation and necrosis, including endocannabinoids (ECbs), which might affect the function of stem cells of the apical papilla (SCAP), cells of paramount importance for root formation, and regenerative endodontic treatment.
Claudia Caroline Bosio Meneses +2 more
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Many mediators are produced during pulp inflammation and necrosis, including endocannabinoids (ECbs), which might affect the function of stem cells of the apical papilla (SCAP), cells of paramount importance for root formation, and regenerative endodontic treatment.
Claudia Caroline Bosio Meneses +2 more
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Apical Papilla Regulates Dental Follicle Fate via the OGN-Hh Pathway
Journal of Dental Research, 2022Root apical complex, including Hertwig’s epithelial root sheath, apical papilla, and dental follicle (DF), is the germinal center of root development, wherein the DF constantly develops into periodontal tissue. However, whether DF development is regulated by the adjacent apical papilla remains largely unknown.
X. Lin +5 more
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Effects of serum-free culture media on human apical papilla cells properties
Archives of Oral Biology, 2021Aiming at more effective and safer cell therapies, the objective of this study was to evaluate the biological properties of human apical papilla cells cultured in the absence of serum supplementation in comparison to cells cultured with fetal bovine serum (FBS).Two apical papilla cell populations were isolated from third molars with incomplete ...
Aline, Queiroz +4 more
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Growth and Differentiation of Dental Stem Cells of Apical Papilla on Polycaprolactone Scaffolds
2018Biodegradable scaffolds are useful tools in the field of tissue engineering and regenerative medicine. The aim of this study was to test the potential of the human stem cells of apical papilla (SCAP) to attach, proliferate and differentiate on a polycaprolactone (PCL)-based scaffolds.
Mohamed, Jamal +4 more
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Journal of Endodontics, 2017
Stem cells from the apical papilla (SCAPs) were suggested as the stem cell source in regenerative endodontic procedures. However, bone and/or cementum-like structure were observed in root canals. Lipopolysaccharide (LPS) in infected root canals might alter SCAPs' osteogenic differentiation pattern.
Veera, Lertchirakarn, Panuroot, Aguilar
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Stem cells from the apical papilla (SCAPs) were suggested as the stem cell source in regenerative endodontic procedures. However, bone and/or cementum-like structure were observed in root canals. Lipopolysaccharide (LPS) in infected root canals might alter SCAPs' osteogenic differentiation pattern.
Veera, Lertchirakarn, Panuroot, Aguilar
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Archives of Oral Biology, 2018
Mesenchymal stem cells (MSCs) have attracted worldwide attention for their capacity to repair damaged tissue, immunosuppression, ability to differentiate into several cell types and their secretome. Earlier studies have demonstrated their angiogenic potential in vitro and in vivo.
Anastasios, Koutsoumparis +4 more
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Mesenchymal stem cells (MSCs) have attracted worldwide attention for their capacity to repair damaged tissue, immunosuppression, ability to differentiate into several cell types and their secretome. Earlier studies have demonstrated their angiogenic potential in vitro and in vivo.
Anastasios, Koutsoumparis +4 more
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Characterization of human apical papilla-derived stem cells.
Journal of biological regulators and homeostatic agents, 2018Dental tissues represent an alternative and promising source of post-natal Mesenchymal stem cells (MSCs) for tissue engineering. Furthermore, dental stem cells from apical papilla (SCAPs) cells can be obtained from the wisdom tooth which is unnecessary for human masticatory function and frequently extracted for orthodontic reasons or dysodontiasis ...
Cantore S +11 more
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Journal of Cellular Physiology, 2010
AbstractStem cells from apical papilla (SCAP) are a novel population of multipotent stem cells that, although similar to dental pulp stem cells, are a discrete source of dental stem cells. SCAP have potential roles in root development, apexogenesis, pulp/dentin regeneration, and bioroot engineering.
Gang, Ding +6 more
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AbstractStem cells from apical papilla (SCAP) are a novel population of multipotent stem cells that, although similar to dental pulp stem cells, are a discrete source of dental stem cells. SCAP have potential roles in root development, apexogenesis, pulp/dentin regeneration, and bioroot engineering.
Gang, Ding +6 more
openaire +2 more sources