Results 31 to 40 of about 178,943 (330)

Production of a soluble and functional recombinant apolipoproteinD in the Pichia pastoris expression system [PDF]

, 2016
ApolipoproteinD (ApoD) is a human glycoprotein from the lipocalin family. ApoD contains a conserved central motif of an 8-stranded antiparallel β-sheet, which forms a beta-barrel that can be used for transport and storage of diverse hydrophobic ligands ...
Armanmehr, S., Kalhor, H.R., Tabarraei, A.   +2 more
core   +1 more source

Denaturation of apolipoprotein A‐I and the monomer form of apolipoprotein A‐I_Milano [PDF]

European Journal of Biochemistry, 1999
In this study the thermal and denaturant induced unfolding of apolipoprotein A‐I (apo A‐I) and the monomer form of apolipoprotein A‐IMilano (apo A‐IM) was followed. Dimer apo A‐IM was reduced with dithiothreitol, which was present in the protein solutions in all experiments.
M, Suurkuusk, D, Hallén
openaire   +2 more sources

A proteomic study of the apolipoproteins in LDL subclasses in patients with the metabolic syndrome and type 2 diabetes

Journal of Lipid Research, 2005
The exchangeable apolipoproteins present in small, dense LDL (sdLDL) and large, buoyant LDL subclasses were evaluated with a quantitative proteomic approach in patients with the metabolic syndrome and with type 2 diabetes, both with subclinical ...
Pia Davidsson, Johannes Hulthe, Björn Fagerberg, Britt-Marie Olsson, Carina Hallberg, Björn Dahllöf, Germán Camejo   +6 more
doaj   +1 more source

Probing the Structure–Function relationship and amyloidogenic propensities in natural variants of apolipoprotein A-I

Biochemistry and Biophysics Reports, 2020
Background: Apolipoprotein A-I (apoA-I) protects against atherosclerosis and participates in the removal of excess cellular cholesterol from peripheral organs. Several naturally occurring apoA-I mutations are associated with familial systemic amyloidosis,
Farah Ma'arfi, Subhash Chandra Prasad, Jamal e Fatima, Mohd Yasir Khan, Snober S. Mir, Mohd Aslam Yusuf   +5 more
doaj   +1 more source

Apolipoprotein A-I Stimulates Secretion of Apolipoprotein E by Foam Cell Macrophages [PDF]

Journal of Biological Chemistry, 1999
Apolipoprotein A-I (apoA-I) overexpression inhibits atherogenesis in mice, and apolipoprotein E (apoE) secreted by foam cell macrophages may exert antiatherogenic effects within the arterial wall. We hypothesized that interaction between apoA-I and apoE contributed to the antiatherogenic properties of apoA-I, and therefore investigated whether apoA-I ...
David M. Rees, T. Sloane, Wendy Jessup, Roger T. Dean, Leonard Kritharides   +4 more
openalex   +4 more sources

Binding of apolipoprotein A-I and acetaldehyde-modified apolipoprotein A-I to liver extracellular matrix [PDF]

Hepatology, 1996
Apolipoprotein A-I (Apo A-I), a protein produced mainly by hepatocytes, is decreased in the sera of alcoholic patients with liver fibrosis and cirrhosis. To explain this decrease, we investigated possible interactions between liver extracellular matrix (ECM) and Apo A-I.
V, Paradis, P, Mathurin, V, Ratziu, T, Poynard, P, Bedossa   +4 more
openaire   +3 more sources

Volumetric determination of apolipoprotein stoichiometry of circulating HDL subspecies1[S]

Journal of Lipid Research, 2013
Although HDL is inversely correlated with coronary heart disease, elevated HDL-cholesterol is not always protective. Additionally, HDL has biological functions that transcend any antiatherogenic role: shotgun proteomics show that HDL particles contain 84
Jere P. Segrest, Marian C. Cheung, Martin K. Jones   +2 more
doaj   +1 more source

Serum apolipoproteins in relation to intakes of fish in population of Arkhangelsk County

Nutrition & Metabolism, 2012
Background Diets rich in omega-3 fatty acids and low in saturated fat were found beneficially associated with blood lipids and cardio-vascular health. Lean reindeer meet and local cold water white-fish species high in omega-3 are among the main sources ...
Petrenya Natalia, Brustad Magritt, Cooper Marie, Dobrodeeva Liliya, Bichkaeva Fatima, Lutfalieva Gulnara, Odland Jon   +6 more
doaj   +1 more source

ApoA-I cleaved by transthyretin has reduced ability to promote cholesterol efflux and increased amyloidogenicity

Journal of Lipid Research, 2007
A fraction of plasma transthyretin (TTR) circulates in HDL through binding to apolipoprotein A-I (apoA-I). Moreover, TTR is able to cleave the C terminus of lipid-free apoA-I.
Márcia Almeida Liz, Cláudio M. Gomes, Maria João Saraiva, Mónica Mendes Sousa   +3 more
doaj   +1 more source

Evaluation of Lipid Profile, Apo B/ Apo A Ratio and Lpa and its Relationship with Cognitive Disorders in the Older Adults: Birjand Longitudinal Aging Study

Archives of Advances in Biosciences, 2023
Introduction: Accurate and timely diagnosis of mild cognitive disorders is essential to prevent their progression to dementia. This study aimed to determine the relationship among the serum levels of lipid markers of cognitive disorders in older adults ...
Sara Hamdamian, Asghar Zarban , Mitra Moodi, Farshad Sharifi, rasoul raesi, Mohammad Dehghani Firoozabadi   +5 more
doaj   +1 more source