Results 31 to 40 of about 92,863 (145)

Assessment of apolipoprotein B/apolipoprotein A-I ratio in non-ST segment elevation acute coronary syndrome patients

The Egyptian Heart Journal, 2020
Background The apolipoprotein B/apolipoprotein A-I ratio was shown to be strongly related to the risk of myocardial infarction in several large-scale studies.
Haitham Galal, Ayman Samir, Mohamed Shehata   +2 more
doaj   +1 more source

Efficacy and Safety of High-Density Lipoprotein/Apolipoprotein A1 Replacement Therapy in Humans and Mice With Atherosclerosis: A Systematic Review and Meta-Analysis

Frontiers in Cardiovascular Medicine, 2021
Background: Although elevation of HDL-C levels by pharmaceutical drugs have no benefit of cardiovascular endpoint, the effect of high-density lipoprotein/apolipoprotein A1 (HDL/apoA-1) replacement therapy on atherosclerosis is controversial.
Ayiguli Abudukeremu, Canxia Huang, Hongwei Li, Runlu Sun, Runlu Sun, Xiao Liu, Xiao Liu, Xiaoying Wu, Xiaoying Wu, Xiangkun Xie, Xiangkun Xie, Jingjing Huang, Jingjing Huang, Jie Zhang, Jie Zhang, Jinlan Bao, Yuling Zhang, Yuling Zhang   +17 more
doaj   +1 more source

D-4F-mediated reduction in metabolites of arachidonic and linoleic acids in the small intestine is associated with decreased inflammation in low-density lipoprotein receptor-null mice

Journal of Lipid Research, 2012
To test the hypothesis that intestine is a major site of action for D-4F, LDLR−/− mice were fed a Western diet (WD) and administered the peptide subcutaneously (SQ) or orally.
Mohamad Navab, Srinivasa T. Reddy, G.M. Anantharamaiah, Greg Hough, Georgette M. Buga, Jan Danciger, Alan M. Fogelman   +6 more
doaj   +1 more source

Apolipoprotein A-I: structure-function relationships.

Journal of lipid research, 2000
The inverse relationship between high density lipoprotein (HDL) plasma levels and coronary heart disease has been attributed to the role that HDL and its major constituent, apolipoprotein A-I (apoA-I), play in reverse cholesterol transport (RCT). The efficiency of RCT depends on the specific ability of apoA-I to promote cellular cholesterol efflux ...
Frank, Philippe, Marcel, Yves
openaire   +3 more sources

Evaluación de las concentraciones de lípidos y apoproteínas A-I y B-100 en un grupo de escolares de cinco departamentos del centro-oriente de Colombia

Biomédica: revista del Instituto Nacional de Salud, 2007
Introducción. Existe evidencia sobre variaciones en las concentraciones de lípidos y apoproteínas en los niños asociados a cambios fisiológicos o al medio ambiente, este último puede inducir alteraciones futuras en los lípidos. Objetivo.
Elpidia Poveda, Ney Callas, César Baracaldo, Carlina Castillo, Patricia Hernández, Martha Guerra   +5 more
doaj   +1 more source

The bridging function of hepatic lipase clears plasma cholesterol in LDL receptor-deficient “apoB-48-only” and “apoB-100-only” mice

Journal of Lipid Research, 2004
Hepatic lipase clears plasma cholesterol by lipolytic and nonlipolytic processing of lipoproteins. We hypothesized that the nonlipolytic processing (known as the bridging function) clears cholesterol by removing apoB-48- and apoB-100-containing ...
Helén L. Dichek, Kun Qian, Nalini Agrawal   +2 more
doaj   +1 more source

Analysis of high density lipoprotein apolipoproteins by capillary zone and capillary SDS gel electrophoresis

Journal of Lipid Research, 1998
We describe new methods for analyzing the apolipoproteins (apo) of the high density lipoproteins (HDL) of several species by two modes of capillary electrophoresis: size separation using a molecular sieving buffer, and capillary zone electrophoresis (CZE)
Joseph Stocks, M. Nazeem Nanjee, Norman E. Miller   +2 more
doaj   +1 more source

The prognostic significance of HDL-associated apolipoproteins in ascitic fluid from patients with cirrhosis and spontaneous bacterial peritonitis

Scientific Reports
Apolipoproteins (Apo) A-I and A-II are major components of high-density lipoproteins (HDL) with immunomodulatory functions. Low serum apoA-I levels indicate complications of cirrhosis. We hypothesized that HDL-associated apolipoproteins in ascitic fluid (
Mohamad Murad, Philipp A. Reuken, Kristin Schubert, Johanna Reißing, Oluwatomi Ibidapo-Obe, Karsten Große, Mick Frissen, Frederic Haedge, Majda El-Hassani, Martin von Bergen, Tony Bruns   +10 more
doaj   +1 more source

Enhancement by LDL of transfer of L-4F and oxidized lipids to HDL in C57BL/6J mice and human plasma

Journal of Lipid Research, 2011
The apoA-I mimetic peptide L-4F [(Ac-D-W-F-K-A-F-Y-D-K-V-A-E-K-F-K-E-A-F-NH2) synthesized from all L-amino acids] has shown potential for the treatment of a variety of diseases. Here, we demonstrate that LDL promotes association between L-4F and HDL. A 2-
David Meriwether, Satoshi Imaizumi, Victor Grijalva, Greg Hough, Ladan Vakili, G.M. Anantharamaiah, Robin Farias-Eisner, Mohamad Navab, Alan M. Fogelman, Srinivasa T. Reddy, Ishaiahu Shechter   +10 more
doaj   +1 more source

Quality control in the apoA-I secretory pathway

Journal of Lipid Research, 2004
From a total of 47 known apolipoprotein A-I (apoA-I) mutations, only 18 are linked to low plasma HDL apoA-I concentrations, and 78% of these map to apoA-I helices 6 and 7 (residues 143–186).
Shaila Bhat, Manal Zabalawi, Mark C. Willingham, Gregory S. Shelness, Michael J. Thomas, Mary G. Sorci-Thomas   +5 more
doaj   +1 more source