Results 91 to 100 of about 18,522 (215)

Lifestyle Intervention During Pregnancy Is Associated With Favourable Changes of Vitronectin in Women With Obesity: Results From the Randomised LiP Trial

Clinical Obesity, Volume 16, Issue 3, June 2026.
ABSTRACT Obesity in pregnancy is a well‐established risk factor for adverse maternal and neonatal outcomes, including gestational diabetes mellitus (GDM). This study aimed to examine the effects of lifestyle intervention during pregnancy on the cardio‐metabolic protein profile and its association with maternal and neonatal health.
Birgitte Moeller Luef, Katrine Sølling Borlund Mortensen, Lasse Møllegaard Obel, Louise Laage Stentebjerg, Per Glud Ovesen, Patrick M. Catalano, Jan Stener Jørgensen, Dorte Møller Jensen, Christina Anne Vinter, Martin Overgaard   +9 more
wiley   +1 more source

Selection of monoclonal antibodies for linear epitopes of an apolipoprotein yields antibodies with comparable affinity for lipid-free and lipid-associated apolipoprotein

Journal of Lipid Research, 1996
A direct approach is described for generating human apolipoprotein (apo) A-I-specific monoclonal antibodies with defined linear epitopes. The antibodies have comparable binding affinity for delipidated apoA-I and apoA-I on high density lipoproteins (HDL).
L K Curtiss, C L Banka
doaj   +1 more source

Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction

Advanced Healthcare Materials, Volume 15, Issue 20, 27 May 2026.
Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang, Jingguo Qu, Tonghuan Xiao, Xinyang Han, Michael Tin‐Cheung Ying   +4 more
wiley   +1 more source

Influence of development, estrogens, and food intake on apolipoprotein A-I, A-II, and E mRNA in rat liver and intestine.

Journal of Lipid Research, 1989
The influence of development and ethinylestradiol (EE) on apolipoprotein (apo) A-I, A-II, and E mRNA in rat liver and intestine was studied by dot blot hybridization and Northern blot analysis.
B Staels, J Auwerx, L Chan, A van Tol, M Rosseneu, G Verhoeven   +5 more
doaj   +1 more source

Insulin Resistance is Associated With Skin Microvascular Dysfunction and Reduced Circulating Endothelial Progenitor Cells in Hypertensive Patients

The Journal of Clinical Hypertension, Volume 28, Issue 5, May 2026.
ABSTRACT Microvascular dysfunction is an early manifestation of vascular damage in patients with hypertension and cardiometabolic disorders. Insulin resistance (IR) is linked closely to vascular dysfunction, and the triglyceride–glucose (TyG) index is a practical proxy marker of IR.
Ya‐Wen Lu, Chun‐Chin Chang, Ruey‐Hsing Chou, Chin‐Sung Kuo, Shih‐Hung Tsai, Po‐Hsun Huang   +5 more
wiley   +1 more source

ABCA1 mediates concurrent cholesterol and phospholipid efflux to apolipoprotein A-I

Journal of Lipid Research, 2004
Prior studies provide data supporting the notion that ATP binding cassette transporter A1 (ABCA1) promotes lipid efflux to extracellular acceptors in a two-step process: first, ABCA1 mediates phospholipid efflux to an apolipoprotein, and second, this ...
Jonathan D. Smith, Wilfried Le Goff, Megan Settle, Gregory Brubaker, Christine Waelde, Andrew Horwitz, Michael N. Oda   +6 more
doaj   +1 more source

Adverse Effects of Low Serum HDL‐C Levels on Prognosis and Tumor Immune Microenvironment in Patients With Newly Diagnosed Chronic Lymphocytic Leukemia

Cancer Medicine, Volume 15, Issue 4, April 2026.
ABSTRACT Disorders of lipid metabolism contribute to the occurrence and progression of hematological malignancies, including chronic lymp hocytic leukemia (CLL). The objective of this study was to investigate the association between serum lipid levels and prognosis in patients with CLL.
Weiran Lv, Shutong Liu, Jiangtao Song, Zhijian Liang, Huaze Liao, Qianqian Huang, Ziang Zhu, Zhoupei Mo, Yun Wang, Yang Liang   +9 more
wiley   +1 more source

Activation of lecithin cholesterol acyltransferase by a disulfide-linked apolipoprotein A-I dimer

, 1997
Apolipoprotein A-I(Milano) is a molecular variant of apoA-I, containing the Arg173→Cys substitution that forms a disulfide linked homodimer (A-I(M)/A-I(M)).
L. Calabresi, A. Jonas, G. Franceschini, A. Burkybile   +3 more
core   +1 more source

Remodelling of reconstituted high density lipoproteins by lecithin: cholesterol acyltransferase

Journal of Lipid Research, 1996
Discoidal reconstituted high density lipoproteins (rHDL) with a diameter of 7.9 nm, a molar ratio of egg phosphatidylcholine (PC): unesterified cholesterol (UC): cholesteryl esters (CE): apolipoprotein (apo) A-I of 33:7:0:1 and containing two molecules ...
H Q Liang, K A Rye, P J Barter
doaj   +1 more source

Apolipoprotein A-I and A-I mimetic peptides: a role in atherosclerosis

, 2011
Godfrey S Getz, Catherine A ReardonThe University of Chicago, Department of Pathology, Chicago, IL, USAAbstract: Cardiovascular disease remains a major cause of morbidity and mortality in the westernized world.
Getz GS, Reardon CA
core