Results 71 to 80 of about 31,566,991 (117)

Incidence of dementia and mild cognitive impairment in two Indigenous Bolivian cohorts

Alzheimer's &Dementia, Volume 22, Issue 9, September 2026.
Abstract INTRODUCTION We studied dementia incidence and risk factors in Indigenous Tsimane and Moseten Amerindian populations in Amazonian Bolivia with largely subsistence lifestyles. METHODS A median of 4.7 years after baseline dementia assessment, 730 participants (52% male; mean age 67.3 years) were re‐visited at two follow‐up phases to determine ...
Margaret Gatz, Wendy J. Mack, Daniel Eid Rodriguez, Raul Quispe Gutierrez, Jesus Bani Cuata, Helena C. Chui, Ellen E. Walters, Daniel K. Cummings, Paul L. Hooper, Henrik Zetterberg, Caleb E. Finch, Benjamin C. Trumble, Jonathan Stieglitz, Michael D. Gurven, Randall C. Thompson, Gregory S. Thomas, The HORUS Team, Tsimane Health and Life History Project, Hillard S. Kaplan   +18 more
wiley   +1 more source

Avaliação do polimorfismo genético e atividade da enzina paroxonase em pacientes hipercolesterolêmicos [PDF]

, 2012
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-Graduação em Farmácia, Florianópolis, 2004.A aterosclerose é a principal causa de morbidade e mortalidade no mundo ocidental e envolve ...
Favarin, Maria Elisa
core  

Apolipoprotein E E3/E4 genotype is associated with an increased risk of coronary atherosclerosis in patients with hypertension

BMC Cardiovascular Disorders
Objective Apolipoprotein E (APOE) gene polymorphisms were associated with coronary atherosclerosis and hypertension. However, the relationship between APOE polymorphisms and coronary atherosclerosis susceptibility in hypertensive patients is unclear. The
Guoliang Wei, Bin Li, Hao Wang, Li Chen, Wenhao Chen, Kehui Chen, Weihong Wang, Shen Wang, Hui Zeng, Yuanliang Liu, Yue Zeng, Hui Rao   +11 more
doaj   +1 more source

The Cog‐Aging: a 15‐year cohort study of cognition in Brazilian older adults

Alzheimer's &Dementia, Volume 22, Issue 9, September 2026.
Abstract BACKGROUND Prevalence of dementia is higher in low‐ and middle‐income countries (LMICs). However, longitudinal studies characterizing cognitive decline and its clinical and epidemiological predictors remain scarce in Brazil. METHODS Participants were enrolled from 2011 to 2025 and followed through May 2026.
Gabriela Tomé Oliveira Engelmann, Joice Coutinho de Alvarenga, Giovanna Correia Pereira Moro, Ivonne Carolina Bolaños Burgos, Mariana Figueiredo Miranda, Millena Figueiredo Miranda, Aline Siqueira de Souza, Marcelle Ferreira Saldanha, Erika Oliveira Hansen, Natalia Silva Dias, Fabiana Carla Matos da Cunha Cintra, Bruna Fulgêncio Dias, Anna Luiza da Silva Souza, Andréa Teixeira Carvalho, Pamela V. Martino‐Adami, Marco Túlio Gualberto Cintra, Ludimila Labanca, Igor Nunes Lanna, Rafaela Teixeira de Ávila, Jonas Jardim de Paula, Luciana Costa‐Silva, Daniela Valadão Freitas Rosa, Débora Marques de Miranda, Marco Aurélio Romano‐Silva, Luiz Armando Cunha de Marco, Alfredo Ramírez, Bernardo de Mattos Viana, Maria Aparecida Camargos Bicalho   +27 more
wiley   +1 more source

Oestrogen replacement therapy may improve memory functioning in the absence of APOE e4 [PDF]

, 2004
There is currently intense controversy regarding the use of hormone replacement therapy (HRT) in postmenopausal women, in relation to its therapeutic efficacy in Alzheimer's disease (AD).
Stuckey, B.G.A., Laws, S.M., Nolan, D., Hewson-Bower, B., Baker, L.D., Foster, J.K., Clarnette, R., Burkhardt, M.S., Martins, R.N., Gandy, S.E., Craft, S.   +10 more
core  

White matter differences between healthy young ApoE4 carriers and non-carriers identified with tractography and support vector machines. [PDF]

, 2012
The apolipoprotein E4 (ApoE4) is an established risk factor for Alzheimer's disease (AD). Previous work has shown that this allele is associated with functional (fMRI) changes as well structural grey matter (GM) changes in healthy young, middle-aged and ...
Lamberton, F., Hampel, Harald, Miller, Julia, Rujescu, D., Laurence O'Dwyer, Lamberton, Franck, Prvulovic, David, Matura, S., Scheibe, M., O'Dwyer, L.G., David Prvulovic, O'Dwyer, Laurence, Hampel, H., Franck Lamberton, Dan Rujescu, Harald Hampel, Scheibe, Monika, Julia Miller, Prvulovic, D., Silke Matura, Monika Scheibe, Matura, Silke, Miller, J., Rujescu, Dan   +23 more
core   +3 more sources

Multiple molecular-genetic defects in a female with mixed hyperlipoproteinemia and earlyischemic heart disease

Терапевтический архив, 2003
Aim. Analysis of genes of apolipoprotein E (apoE), LDLP receptor and methylentetrahydrofolate reductase (MTHFR) in a female patient with mixed hyperlipoproteinemia (HLP) and early ischemic heart disease (IHD). Material and methods. A patient with a mixed
P P Malyshev, D V Stambolsky, A N Meshkov, Yu V Davydova, V V Kukharchuk   +4 more
doaj  

Gene-regulatory activity of alpha-tocopherol. [PDF]

, 2010
Vitamin E is an essential vitamin and a lipid soluble antioxidant, at least, under in vitro conditions. The antioxidant properties of vitamin E are exerted through its phenolic hydroxyl group, which donates hydrogen to peroxyl radicals, resulting in ...
Lodge, John K., Gerald Rimbach, Jennifer Moehring, Rimbach, G., Moehring, J., Huebbe, Patricia, John K. Lodge, Huebbe, P., Lodge, John, Rimbach, Gerald, Patricia Huebbe, Moehring, Jennifer, Rimbach, Moehring, Huebbe, Lodge   +15 more
core   +1 more source

Apolipoprotein E genotype and neurodevelopmental sequelae of infant cardiac surgery [PDF]

, 2003
BackgroundThere has been increasing recognition of adverse neurodevelopmental sequelae in some children after repair of congenital heart defects.
Gaynor, J.William, Newman, Mark F, Zackai, Elaine H, Gerdes, Marsha, Wernovsky, Gil, Spray, Thomas L, D'Agostino, Jo Ann, Jarvik, Gail P, Clancy, Robert R, Heagerty, Patrick J, Saunders, Ann M, Bernbaum, Judy, Nicolson, Susan C, McDonald-McGinn, Donna   +13 more
core   +1 more source

Apolipoprotein E promoter polymorphisms do not have a major influence on the risk of developing primary open angle glaucoma

Purpose: Primary open angle glaucoma (POAG) is a major cause of late onset visual failure of unknown etiology. Recent genetic association studies have implicated the apolipoprotein E (APOE) gene in the pathophysiology of primary open angle glaucoma, but ...
Birch M, Ressiniotis T, Griffiths PG, Chinnery PF, Keers SM   +4 more
core   +5 more sources