Results 31 to 40 of about 64,253 (284)
Combined aptamer and transcriptome sequencing of single cells. [PDF]
, 2018 The transcriptome and proteome encode distinct information that is important for characterizing heterogeneous biological systems. We demonstrate a method to simultaneously characterize the transcriptomes and proteomes of single cells at high throughput ...
Abate, Adam R +3 more
core +2 more sources
Indonesian Journal of Chemistry, 2021 Inaccurate diagnoses contributes to the high mortality rate of breast cancer. Human epidermal growth factor receptor 2 (HER2) is overexpressed in breast cancer tumors at around 20–30%.
Yeni Wahyuni Hartati +5 more
doaj +1 more source
Chemistry & Biology, 2002 A controllable, intracellular RNA aptamer could be an invaluable therapeutic or discovery reagent. A report published in this journal shows that aptamer behavior can be regulated by a small molecule, paving the way for the development of more sophisticated ligand-regulated aptamers.
openaire +2 more sources
Timing molecular motion and production with a synthetic transcriptional clock [PDF]
, 2011 The realization of artificial biochemical reaction networks with unique functionality is one of the main challenges for the development of synthetic biology. Due to the reduced number of components, biochemical circuits constructed in vitro promise to be
Atkinson +34 more
core +3 more sources
, 2018 Aptamers are in vitro selected oligonucleotides capable of specific, high-affinity binding to a wide variety of target molecules. These features enable their application in diagnostics, therapeutics, targeted delivery, fluorescence imaging, and biosensing.
Andrew Brian Kinghorn (Ed.) +2 more
openaire +1 more source
Molecular Docking Insight into the Label-Free Fluorescence Aptasensor for Ochratoxin A Detection
Molecules, 2023 Ochratoxin A (OTA) is the most common mycotoxin and can be found in wheat, corn and other grain products. As OTA pollution in these grain products is gaining prominence as a global issue, the demand to develop OTA detection technology has attracted ...
Hua Ye +7 more
doaj +1 more source
Aptamer-Modified Semiconductor Quantum Dots for Biosensing Applications
Sensors, 2017 Semiconductor quantum dots have attracted extensive interest in the biosensing area because of their properties, such as narrow and symmetric emission with tunable colors, high quantum yield, high stability and controllable morphology.
Lin Wen +4 more
doaj +1 more source
Research progress on the role of vitamin D supplementation in adjuvant therapy for COVID-19 [PDF]
Xin yixue, 2022 The pandemic caused by coronavirus disease of 2019 （COVID-19） has brought severe challenges to public health all over the world. Vitamin D plays an important role in immune regulation and anti-respiratory virus infection as an immune enhancer.
Lei Yan, Zhan Shihuai, Shi Xiaohua, Wang Shuiliang, Zhao Meng, Zhang Shenghang
doaj +1 more source
Aptamer-based therapeutics and their potential in radiopharmaceutical design [PDF]
, 2007 Aptamers, short, single stranded oligonucleotide entities, have been developed in the past 15 years against a plethora of targets and for a variety of applications.
Ferreira, Catia S. M. +1 more
core +3 more sources
Beilstein Journal of Organic Chemistry, 2020 For the first time, a metal-mediated base pair has been used to modulate the affinity of an aptamer towards its target. In particular, two artificial imidazole 2’-deoxyribonucleosides (Im) were incorporated into various positions of an established ATP ...
Marius H. Heddinga, Jens Müller
doaj +1 more source