Results 41 to 50 of about 68,358 (287)
Indonesian Journal of Chemistry, 2021 Inaccurate diagnoses contributes to the high mortality rate of breast cancer. Human epidermal growth factor receptor 2 (HER2) is overexpressed in breast cancer tumors at around 20–30%.
Yeni Wahyuni Hartati +5 more
doaj +1 more source
Aptamer-Modified Semiconductor Quantum Dots for Biosensing Applications
Sensors, 2017 Semiconductor quantum dots have attracted extensive interest in the biosensing area because of their properties, such as narrow and symmetric emission with tunable colors, high quantum yield, high stability and controllable morphology.
Lin Wen +4 more
doaj +1 more source
Machine learning guided aptamer refinement and discovery
Nature Communications, 2021 Aptamers are single-stranded nucleic acid ligands that bind to target molecules with high affinity and specificity. They are typically discovered by searching large libraries for sequences with desirable binding properties.
A. Bashir +16 more
semanticscholar +1 more source
DNA module platform for developing colorimetric aptamer sensors
BioTechniques, 2016 Here we present a DNA module platform for developing simple aptamer sensors based on a microarray format combined with secondary structure prediction in silico.
Yasuyuki Tomita +3 more
doaj +1 more source
Beilstein Journal of Organic Chemistry, 2020 For the first time, a metal-mediated base pair has been used to modulate the affinity of an aptamer towards its target. In particular, two artificial imidazole 2’-deoxyribonucleosides (Im) were incorporated into various positions of an established ATP ...
Marius H. Heddinga, Jens Müller
doaj +1 more source
Biosensors and Bioelectronics: X, 2022 In this work, a liquid crystal (LC)-based aptasensor for okadaic acid (OA) detection was developed with a novel aptamer mechanism for enhancing the optical signals of LCs.
Zeinab Rouhbakhsh +3 more
doaj +1 more source
Biosensors, 2022 Nucleic-acid aptamers consisting in single-stranded DNA oligonucleotides emerged as very promising biorecognition elements for electrochemical biosensors applied in various fields such as medicine, environmental, and food safety.
Andra Mihaela Onaş +3 more
doaj +1 more source
2D graphene oxide–aptamer conjugate materials for cancer diagnosis
npj 2D Materials and Applications, 2021 2D graphene oxide (GO) with large surface area, multivalent structure can easily bind single-stranded DNA/RNA (aptamers) through hydrophobic/π-stacking interactions, whereas aptamers having small size, excellent chemical stability and low immunogenicity ...
S. Sekhon +3 more
semanticscholar +1 more source
Advanced Functional Materials, EarlyView.A multivalent antiviral platform based on honeycomb‐shaped DNA nanostructures (HC–Urumin) is developed to enhance the potency and breadth of the host defense peptide Urumin. Through spatially patterned trimeric presentation, HC–Urumin disrupts influenza A virus entry, improves cell viability, and reduces disease severity in vivo‐offering a modular and ...
Saurabh Umrao +11 more
wiley +1 more source
Advanced Science, 2022 Increasing antibiotic resistance becomes a serious threat to public health. Photothermal therapy (PTT) and antibacterial enzyme‐based therapy are promising nonresistant strategies for efficiently killing drug‐resistant bacteria.
Zhangkun Liu +6 more
doaj +1 more source