Results 11 to 20 of about 29,754 (236)
Progress on application of aptamers on food safety detection
Zhongguo shipin weisheng zazhi, 2022 Aptamers are DNA or RNA molecules that can bind to their target molecules with high affinity and specificity， and because aptamers are stable， simply synthesized and chemically modified， aptamers have become useful tools for analytical， diagnostic and ...
LI Na, WANG Ming, YUAN Jinglei
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Characterization of MNK1b DNA Aptamers That Inhibit Proliferation in MDA-MB231 Breast Cancer Cells
Molecular Therapy: Nucleic Acids, 2016 Elevated expression levels of eukaryotic initiation factor 4E (eIF4E) promote cancer development and progression. MAP kinase interacting kinases (MNKs) modulate the function of eIF4E through the phosphorylation that is necessary for oncogenic ...
Eva M García-Recio +6 more
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Aptamer Technology and Its Applications in Bone Diseases
Cell Transplantation, 2023 Aptamers are single-stranded nucleic acids (DNA, short RNA, or other artificial molecules) produced by the Systematic Evolution of Ligands by Exponential Enrichment (SELEX) technology, which can be tightly and specifically combined with desired targets ...
Xiangzhong Liu +7 more
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Molecular Therapy: Nucleic Acids, 2016 The genetic diversity of the influenza virus hinders the use of broad spectrum antiviral drugs and favors the appearance of resistant strains. Single-stranded DNA aptamers represent an innovative approach with potential application as antiviral compounds.
Paloma Rodriguez +4 more
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Frontiers in Microbiology, 2021 Largemouth bass virus (LMBV) is one of the most devastating viral pathogens in farmed Largemouth bass. Aptamers are novel molecule probes and have been widely applied in the field of efficient therapeutic and diagnostic agents development.
Qing Yu +11 more
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Biosensors, 2017 In the last years, great progress has been accomplished in the development of aptamer sensors with different transducers. In order to improve the sensitivity of these biosensors, several methodologies have been employed. In this Special Issue, the state of art and the future trends in the field of aptamer sensors have been explored.
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Aptamers and Aptamer-Coupled Biosensors to Detect Water-Borne Pathogens
Frontiers in Microbiology, 2021 Aptamers can serve as efficient bioreceptors for the development of biosensing detection platforms. Aptamers are short DNA or RNA oligonucleotides that fold into specific structures, which enable them to selectively bind to target analytes.
Mariam Saad +3 more
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Modelling aptamers with nucleic acid mimics (NAM): From sequence to three-dimensional docking
PLoS ONE, 2022 Aptamers are single-stranded oligonucleotides, formerly evolved by Systematic Evolution of Ligands by EXponential enrichment (SELEX), that fold into functional three-dimensional structures.
Ricardo Oliveira +5 more
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Scientific Reports, 2021 Tosyl activated magnetic beads were used for aptamer selection against PAG- 7 and 18 proteins of bovine origin. PAG proteins were immobilized on beads with further addition of biotin tagged aptamer library.
Munna Lal Yadav +5 more
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Electrochemistry, 2021 Field effect transistor (FET) biosensors are capable of detecting various biomolecules, although challenges remain in the detection of uncharged molecules.
Hiroki HAYASHI +9 more
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