Results 11 to 20 of about 15,648 (185)
DNA Aptamers in the Diagnosis and Treatment of Human Diseases [PDF]
Molecules, 2015 Aptamers have a promising role in the field of life science and have been extensively researched for application as analytical tools, therapeutic agents and as vehicles for targeted drug delivery.
Qinchang Zhu, Ge Liu, Masaaki Kai
doaj +2 more sources
The life marker chip : potential use of aptamers against small molecules and consideration of instrument planetary protection [PDF]
, 2013 The Life Marker Chip (LMC) instrument was developed with the aim to detect evidence of life on Mars. The detection was based on an inhibition immunoassay. In this work aptamers were evaluated as potential alternative to antibodies for the LMC.
Rato, Carla Cristina Pereira Salgueiro Catarino
core +7 more sources
Preliminary in vivo characterization of a theranostic aptamer: Sgc8-c- DOTA-67Ga [PDF]
, 2017 Nucleic acid aptamers can recognise their target with high affinity and specificity, and their potential as molecular imaging agents and use in theranostics are being explored.
Cerecetto, Hugo +9 more
core +7 more sources
, 2008 Aptamers are single-stranded DNA or RNA molecules isolated in vitro by a selection and amplification method. Aptamers bind with high specificity and affinity to a wide range of target molecules, with dissociation constant comparable to antibodies.
Bini, Alessandra
core +7 more sources
Progress on application of aptamers on food safety detection
Zhongguo shipin weisheng zazhi, 2022 Aptamers are DNA or RNA molecules that can bind to their target molecules with high affinity and specificity， and because aptamers are stable， simply synthesized and chemically modified， aptamers have become useful tools for analytical， diagnostic and ...
LI Na, WANG Ming, YUAN Jinglei
doaj +1 more source
Aptamers and Aptamer-Coupled Biosensors to Detect Water-Borne Pathogens
Frontiers in Microbiology, 2021 Aptamers can serve as efficient bioreceptors for the development of biosensing detection platforms. Aptamers are short DNA or RNA oligonucleotides that fold into specific structures, which enable them to selectively bind to target analytes.
Mariam Saad +3 more
doaj +1 more source
Peptide aptamers define distinct EB1- and EB3-binding motifs and interfere with microtubule dynamics [PDF]
, 2014 EB1 is a conserved protein that plays a central role in regulating microtubule dynamics and organisation. It binds directly to microtubule plus ends and recruits other plus end localising proteins.
Warbrick, Emma +2 more
core +1 more source
Modelling aptamers with nucleic acid mimics (NAM): From sequence to three-dimensional docking
PLoS ONE, 2022 Aptamers are single-stranded oligonucleotides, formerly evolved by Systematic Evolution of Ligands by EXponential enrichment (SELEX), that fold into functional three-dimensional structures.
Ricardo Oliveira +5 more
doaj +2 more sources
Scientific Reports, 2021 Tosyl activated magnetic beads were used for aptamer selection against PAG- 7 and 18 proteins of bovine origin. PAG proteins were immobilized on beads with further addition of biotin tagged aptamer library.
Munna Lal Yadav +5 more
doaj +1 more source
Electrochemistry, 2021 Field effect transistor (FET) biosensors are capable of detecting various biomolecules, although challenges remain in the detection of uncharged molecules.
Hiroki HAYASHI +9 more
doaj +1 more source