Results 31 to 40 of about 29,754 (236)

Screening and Application of DNA Aptamers for Heparin-Binding Protein

open access: yesMolecules
Rapid detection of heparin-binding protein (HBP) is essential for timely intervention in sepsis cases. Current detection techniques are usually antibody-based immunological methods, which have certain problems, such as complexity and slow detection, and ...
Xi Zhou   +9 more
doaj   +1 more source

Programmable DNA‐Peptide Hybrid Nanostructures for Potent Neutralization of Multiple Influenza a Virus Subtypes

open access: yesAdvanced Functional Materials, EarlyView.
A multivalent antiviral platform based on honeycomb‐shaped DNA nanostructures (HC–Urumin) is developed to enhance the potency and breadth of the host defense peptide Urumin. Through spatially patterned trimeric presentation, HC–Urumin disrupts influenza A virus entry, improves cell viability, and reduces disease severity in vivo‐offering a modular and ...
Saurabh Umrao   +11 more
wiley   +1 more source

Electrochemically Driven Dissipative Growth of Affinity Hydrogels for Bioresponsive Interfaces

open access: yesAdvanced Functional Materials, EarlyView.
Voltage pulses drive the growth and reinforcement of hydrogel films under dissipative conditions. This biocompatible strategy enables efficient integration of affinity ligands into the hydrogel matrix, enhancing the selective capture of growth factors and allowing precise temporal control over their release, making them well‐suited as adaptive ...
Roberto Baretta, Marco Frasconi
wiley   +1 more source

Recent Advances in Fluorescent Nanoparticles for Stimulated Emission Depletion Imaging

open access: yesBiosensors
Stimulated emission depletion (STED) microscopy, as a popular super-resolution imaging technique, has been widely used in bio-structure analysis and resolving the dynamics of biological processes beyond the diffraction limit.
Liqing Qi   +11 more
doaj   +1 more source

Applications of Aptamer-Bound Nanomaterials in Cancer Therapy

open access: yesBiosensors, 2021
Cancer is still a major disease that threatens human life. Although traditional cancer treatment methods are widely used, they still have many disadvantages.
Liangxi Zhu   +6 more
doaj   +1 more source

Aptamer–Drug Conjugates [PDF]

open access: yesBioconjugate Chemistry, 2015
Western medicine often aims to specifically treat diseased tissues or organs. However, the majority of current therapeutics failed to do so owing to their limited selectivity and the consequent "off-target" side effects. Targeted therapy aims to enhance the selectivity of therapeutic effects and reduce adverse side effects.
Guizhi, Zhu, Gang, Niu, Xiaoyuan, Chen
openaire   +2 more sources

Impact of Surface Functionalization on NV Quantum Properties: Implications for Biosensing with Fluorescent Nanodiamonds

open access: yesAdvanced Functional Materials, EarlyView.
Fluorescent nanodiamonds (fNDs) have emerged as an invaluable quantum sensing platform for biological and biochemical systems. This paper investigates the influence of common surface functionalization strategies for bioconjugation on the quantum properties of nitrogen vacancy (NV) centers in nanodiamonds.
Anja Sadžak   +6 more
wiley   +1 more source

Hierarchical core–shell DNA condensates enable programmable information storage and encryption

open access: yesNature Communications
Utilizing DNA’s molecular programmability, massive parallelism, and minimal energy requirements, it emerges as a transformative medium for secure data storage and encryption.
Likang Chu   +8 more
doaj   +1 more source

Aptamers: An Emerging Tool for Diagnosis and Therapeutics in Tuberculosis

open access: yesFrontiers in Cellular and Infection Microbiology, 2021
Tuberculosis (TB) has been plaguing human civilization for centuries, and currently around one-third of the global population is affected with TB.
Shruti Srivastava   +2 more
doaj   +1 more source

RNA‐Micelles as Self‐Assembling Structures for Efficient Co‐Delivery of Synergistic siRNA and Nucleoside Analogues to Treat CRC Lung Metastasis

open access: yesAdvanced Functional Materials, EarlyView.
Two kinds of self‐assembled RNA micelles were used to co‐deliver synergistic siRNA and nucleoside analogues for the treatment of colorectal cancer lung metastases. Near‐complete elimination of lung cancer metastases was confirmed in an orthotopic lung metastasis model constructed using human colorectal cancer lung metastases patient surgical samples to
Kai Jin   +4 more
wiley   +1 more source

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