Changes in retinal aquaporin-9 (AQP9) expression in glaucoma [PDF]
Bioscience Reports, 2013 The eye contains numerous water channel proteins and the roles of AQPs (aquaporins) in the retina are blurred, especially under disease conditions. The purpose of this study was to investigate the expression of AQP9 gene and proteins affected by elevated
Ming‑Hui Yang +2 more
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Targeted deletion of the aquaglyceroporin AQP9 is protective in a mouse model of Parkinson's disease. [PDF]
PLoS ONE, 2018 More than 90% of the cases of Parkinson's disease have unknown etiology. Gradual loss of dopaminergic neurons of substantia nigra is the main cause of morbidity in this disease. External factors such as environmental toxins are believed to play a role in
Katja Stahl +12 more
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Tumor‐Associated Neutrophils Regulate Breast Cancer Progression Through the AQP9/STAT3 Signaling Pathway [PDF]
Cancer ScienceXu W +5 more
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Low expression of AQP9 and its value in hepatocellular carcinoma [PDF]
Translational Cancer Research, 2021 The mortality rate for liver cancer is high worldwide. The etiology of liver cancer has altered with the high incidence rate of non-alcoholic fatty liver disease (NAFLD) although effective vaccination strategies have been developed. Therefore, it is important to discover new biomarkers for diagnosis and prognosis.
Gao, Cheng +6 more
openaire +2 more sources
Maternal protein restriction affects the differentiation of cells in the epididymal epithelium lining of 44-day-old rats [PDF]
Biology OpenFábio Colonheze +5 more
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Aquaporin-9 facilitates liver regeneration following hepatectomy
Redox Biology, 2022 Aquaporin-9 (AQP9) is an aquaglyceroporin strongly expressed in the basolateral membrane of hepatocytes facing the sinusoids. AQP9 is permeable to hydrogen peroxide (H2O2) and glycerol as well as to water.
Bo Zhang +9 more
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AQP9 expression in glioblastoma multiforme tumors is limited to a small population of astrocytic cells and CD15(+)/CalB(+) leukocytes. [PDF]
PLoS ONE, 2013 Aquaporin-9 (AQP9) is a membrane protein channel that is permeable to a range of small solutes, including glycerol, urea and nucleobases. Expression of AQP9 in normal brain is limited, while widespread AQP9 expression has previously been reported in ...
Sabina Jelen +5 more
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Frontiers in Cellular and Infection Microbiology, 2021 Hepatocyte invasion by Plasmodium sporozoites represents a promising target for innovative antimalarial therapy, but the molecular events mediating this process are still largely uncharacterized. We previously showed that Plasmodium falciparum sporozoite
Nadia Amanzougaghene +23 more
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Characterization of the Aquaporin-9 Inhibitor RG100204 In Vitro and in db/db Mice
Cells, 2022 Aquaporin-9 (AQP9) is a facilitator of glycerol and other small neutral solute transmembrane diffusion. Identification of specific inhibitors for aquaporin family proteins has been difficult, due to high sequence similarity between the 13 human isoforms,
Marilina Florio +11 more
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Using kICS to Reveal Changed Membrane Diffusion of AQP-9 Treated with Drugs
Membranes, 2021 The formation of nanodomains in the plasma membrane are thought to be part of membrane proteins regulation and signaling. Plasma membrane proteins are often investigated by analyzing the lateral mobility.
Jakob L. Kure +6 more
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