Results 91 to 100 of about 99,139,021 (297)
CRISPR and Gene Augmentation Rescue Trabecular Meshwork Dysfunction in iPSC Models of Lowe Syndrome
Advanced Science, EarlyView.By modeling Lowe syndrome using patient‐derived iPSCs, this study establishes a human disease model that faithfully recapitulates OCRL deficiency‐associated ciliary and cytoskeletal defects. The model enables evaluation of both mutation‐agnostic DNA augmentation and CRISPR‐mediated mutation correction strategies, both of which restore OCRL function and
Siyu Chen +11 more
wiley +1 more source
Aquaporin 4 expression is downregulated in large bovine ovarian follicles
Journal of Animal Reproduction and Biotechnology, 2020 Aquaporin channels (AQPs) are known to play an important role in the development of ovarian follicles through their function in water transport pathways. Compared to other AQPs, research on the role of AQP4 in female reproductive physiology, particularly
Chang-Woon Kim +5 more
doaj +1 more source
Gas-tight triblock-copolymer membranes are converted to CO2 permeable by insertion of plant aquaporins [PDF]
, 2012 We demonstrate that membranes consisting of certain triblock-copolymers were tight for CO2. Using a novel approach, we provide evidence for aquaporin facilitated CO2 diffusion.
Itel, Fabian +11 more
core +1 more source
Advanced Science, EarlyView.Neuronal activation leads to astrocytic transient volume changes, activating transient receptor potential ankyrin 1 (TRPA1) channels, leading to Ca2+ influx. Activation of TRPA1 causes the release of D‐serine through BEST1. Finally, the augmented extracellular levels of D‐serine boost neuronal activity by binding GluN1‐containing NMDARs, leading to CBV
Kayoung Han +11 more
wiley +1 more source
Toward Rational Design of Aqueous Battery Membranes Beyond the Selectivity‐Conductivity Trade‐Off
Advanced Science, EarlyView.This review examines sulfonated membranes for redox flow batteries. It focuses on proton transport mechanism, membrane design, performance limits, optimization strategies, and the pathway from molecular design to membrane manufacturing. ABSTRACT Electrochemical energy‐storage systems increasingly require membranes that can simultaneously deliver fast ...
Jinkang Liu +13 more
wiley +1 more source
Aquaporin-4 and traumatic brain edema.
Chinese journal of traumatology = Zhonghua chuang shang za zhi, 2010 Brain edema leading to an expansion of brain volume has a crucial impact on morbidity and mortality following traumatic brain injury as it increases intracranial pressure, impairs cerebral perfusion and oxygenation, and contributes to additional ischemic injuries.
XU, Miao, SU, Wei, XU, Qiu-ping
openaire +2 more sources
, 2015 Neuromyelitis optica spectrum disorder as a paraneoplastic manifestation of lung adenocarcinoma expressing aquaporin ...
Rindi, Guido +7 more
core +1 more source
Renal expression and functions of aquaporin 1 and aquaporin 4 in cattle [PDF]
, 2013 Aquaporin (AQP) 1 and AQP 4 are members of the aquaporin water channel family that play an important role in reabsorption of water from the renal tubular fluid to concentrate urine. Studies of renal AQPs have been performed in human, rodents, sheep, dogs
Akosman, M. S. +3 more
core +1 more source
The Anatomical Record, EarlyView.Abstract The organization and function of reptilian excurrent ducts remain poorly characterized, particularly in Neotropical snakes. We provide the first integrative morphological, histochemical, immunohistochemical, and ultrastructural analysis of the proximal post‐testicular ducts of Crotalus durissus across reproductive stages.
Flávia Cappuccio de Resende +9 more
wiley +1 more source
Neuromyelitis optica - an update: 2007-2009
Annals of Indian Academy of Neurology, 2009 Neuromyelitis optica is an inflammatory demyelinating disorder of the central nervous system. The discovery of a specific antibody (NMO IgG /aquaporin-4 antibody) in patients with this condition has led to a marked revival of research on the disease ...
Jacob Anu
doaj