Results 101 to 110 of about 9,338,478 (297)

Quantum Phenomena in Molecular and Biological Systems: A Decoherence‐Based Decision Framework With Falsifiable Predictions and a Failure‐Mode Taxonomy

Advanced Physics Research, EarlyView.
A physics‐grounded framework based on decoherence timescales (τ_dec vs τ_func), Markovian validity, and falsifiability criteria is applied across molecular systems to distinguish where quantum effects are necessary, marginal, or irrelevant. The analysis integrates quantum chemistry, biological quantum mechanisms, and quantum computing under a unified ...
Sarfaraz K. Niazi
wiley   +1 more source

Detection of anti-aquaporin-4 autoantibodies in the sera of Chinese neuromyelitis optica patients.

, 2013
In this study, we recruited 10 neuromyelitis optica patients, two multiple sclerosis patients and two myelitis patients. Chinese hamster lung fibroblast (V79) cells transfected with a human aquaporin-4-mCherry fusion protein gene were used to detect anti-
PISANI, FRANCESCO, FRIGERI, Antonio, Wang J, Li M, Su W, Ma T.   +5 more
core   +1 more source

Clock Genes Regulate Ca2+ Signaling and Mitochondrial Bioenergetics to Inhibit Sjögren Disease

Arthritis &Rheumatology, EarlyView.
Objective Although Ca2+ signaling and metabolism have been identified as key determinants for the development of Sjögren disease (SjD), the intricate connection between them and salivary gland physiology remains poorly understood. Methods Fluorescence‐based Ca2+ imaging, RNA sequencing, and mitochondrial activity were used to investigate the effects of
Viktor R. Drel, Manigandan Venkatesan, Rahul S. Jasrotia, Yuyang Sun, Viviane Nascimento da Conceicao, Neelanjan Vishnu, Shankara N. Varadarajan, Venugopal R. Bovilla, Rajender K. Motiani, Shobhan Gaddameedhi, Bibhuti B. Mishra, Muniswamy Madesh, Brij B. Singh   +12 more
wiley   +1 more source

Distinct serum and cerebrospinal fluid cytokine and chemokine profiles in autoantibody-associated demyelinating diseases

Multiple Sclerosis Journal - Experimental, Translational and Clinical, 2019
Background Demyelinating diseases of the central nervous system associated with autoantibodies against aquaporin-4 and myelin-oligodendrocyte-glycoprotein are mediated by different immunopathological mechanisms compared to multiple sclerosis.
Livia S Hofer, Sara Mariotto, Sebastian Wurth, Sergio Ferrari, Chiara R Mancinelli, Rachele Delogu, Salvatore Monaco, Alberto Gajofatto, Carmen Schwaiger, Kevin Rostasy, Florian Deisenhammer, Romana Höftberger, Thomas Berger, Markus Reindl   +13 more
doaj   +1 more source

Nanomaterial‐based immune therapeutic strategies in neurodegenerative diseases

BMEMat, EarlyView.
This review highlights the immunomodulatory potential of nanomaterials (NMs) in treating neurodegenerative diseases (NDs). It focuses on their roles in regulating innate and adaptive immune responses to maintain immune homeostasis. By providing insights into these mechanisms, the review lays the groundwork for innovative NMs therapeutic strategies to ...
Xinru Zhou, Jia Liu, Shulin Lai, Suhan Yin, Bingmin Luo, Longquan Shao, Yiyuan Kang   +6 more
wiley   +1 more source

Update on the intriguing roles of AQP4 expression and redistribution in the progression and treatment of glioma

Annals of Medicine
Aquaporin 4 (AQP4) is abundant in the human brain and has an important role in brain homeostasis and diseases. AQP4 expression has been found to be associated with glioma malignancies.
Yu-Long Lan, Shuang Zou, Ruoli Chen
doaj   +1 more source

PENGARUH BISAKODIL TERHADAP EKSPRESI TRANSPORTER AQUAPORIN-3, AQUAPORIN-4 DAN PPARγ PADA KONSTIPASI YANG DIINDUKSI MORFIN [PDF]

, 2019
Morphine is an opioid analgesic used to treat acute pain and chronic pain. Morphine can cause constipation due to the effect on the enteric nervous system and increased level of aquaporin transporter expression in colon. The administration of morphine is
PUJI LISTIANA RAHAYU, 051511133171
core  

Characterization of Eukaryotic Aquaporin Regulation [PDF]

Aquaporins, as transmembrane proteins essential for cellular water balance maintenance, are increasingly recognized for their modulation by protein-protein interactions, often implicated in various human pathologies. This thesis explores the function and
Glas, Jessica
core   +1 more source

Renal expression and functions of aquaporin 1 and aquaporin 4 in cattle [PDF]

, 2013
Aquaporin (AQP) 1 and AQP 4 are members of the aquaporin water channel family that play an important role in reabsorption of water from the renal tubular fluid to concentrate urine. Studies of renal AQPs have been performed in human, rodents, sheep, dogs
Akosman, M. S., Ozden-Akkaya, O., Cevik-Demirkan, A., Altunbas, K.   +3 more
core   +1 more source

Role of Aquaporin-4 in Cerebral Edema and Stroke [PDF]

, 2008
Cerebral edema plays a central role in the pathophysiology of many diseases of the central nervous system (CNS) including ischemia, trauma, tumors, inflammation, and metabolic disturbances. The formation of cerebral edema results in an increase in tissue water content and brain swelling which, if unchecked, can lead to elevated intracranial pressure ...
Zador, Zsolt, Stiver, Shirley, Wang, Vincent, Manley, Geoffrey T   +3 more
openaire   +3 more sources