Results 241 to 250 of about 49,483 (288)

Cerebrospinal 14-3-3 Protein Levels as a Neuroaxonal Biomarker in Aquaporin-4 Antibody-Positive Neuromyelitis Optica Spectrum Disorder. [PDF]

open access: yesNeurol Neuroimmunol Neuroinflamm
Villacieros-Álvarez J   +24 more
europepmc   +1 more source

The Aquaporin-4 Expression and Localization in the Olfactory Epithelium Modulate the Odorant-Evoked Responses and Olfactory-Driven Behavior. [PDF]

open access: yesGlia
Lobraico D   +8 more
europepmc   +1 more source

AER-270 and TGN-020 are not aquaporin-4 water channel blockers

open access: yes
Unger L   +19 more
europepmc   +1 more source

Aquaporin‐4 and epilepsy

Glia, 2012
AbstractRecent studies have implicated glial cells in modulation of synaptic transmission, so it is plausible that glial cells may have a functional role in the hyperexcitability characteristic of epilepsy. Indeed, alterations in distinct astrocyte membrane channels, receptors, and transporters have all been associated with the epileptic state.
Devin K, Binder   +2 more
openaire   +2 more sources

Aquaporin-4 and Alzheimer’s Disease

Journal of Alzheimer's Disease, 2016
Alzheimer’s disease (AD) is the most common form of dementia. Although the pathogenesis of AD remains unclear, AD is thought to result from an imbalance in the production and clearance of amyloid-β protein (Aβ). Aquaporin-4 (AQP4) is the major aquaporin in the mammalian brain, is mostly expressed on astrocytic endfeet, and functions as a water ...
Canhong, Yang   +7 more
openaire   +2 more sources

Neurological autoimmunity targeting aquaporin-4

Neuroscience, 2010
Neuromyelitis optica (NMO) is the first inflammatory autoimmune demyelinating disease of the CNS for which a specific tissue target molecule has been identified--the astrocytic water channel aquaporin-4 (AQP4). Immunological insights have propelled significant advances in understanding the clinical, radiologic and immunopathologic characteristics of ...
S R, Hinson, A, McKeon, V A, Lennon
openaire   +2 more sources

Aquaporin-4 in hepatic encephalopathy

Metabolic Brain Disease, 2007
Brain edema is a critical component of hepatic encephalopathy (HE) associated with acute liver failure and such edema appears to be principally due to astrocyte swelling (cytotoxic edema). Ammonia is believed to represent a major factor responsible for astrocyte swelling, although the mechanisms by which ammonia causes such swelling are not completely ...
K V, Rama Rao, M D, Norenberg
openaire   +2 more sources

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