Integrative Medicine Research, 2019 An herbal medicine prescription, Oreongsan (ORS), which is composed of Polyporus, Alismatis Rhizoma, Atractylodis Rhizoma, Poria (Hoelen), and Cinnamomi Cortex Spissus, has been used as treatment in patients with various symptoms such as thirst ...
Seungwon Kwon, Chul Jin, Ki-Ho Cho
doaj +1 more source
Significance of molecular biomarkers in the diagnosis of neuromyelitis optica spectrum disorder [PDF]
Medicinski PodmladakDiscovery of antibodies to aquaporin-4 channels as a laboratory or molecular biomarker for neuromyelitis optica spectrum disorder contributed to a better understanding of the etiopathogenesis, with a clear separation of the clinical, neuroradiological ...
Andabaka Marko +2 more
doaj +1 more source
Congestive heart failure in rats is associated with increased expression and targeting of aquaporin-2 water channel in collecting duct [PDF]
, 1997 We tested whether severe congestive heart failure (CHF), a condition associated with excess free-water retention, is accompanied by altered regulation of the vasopressin-regulated water channel, aquaporin-2 (AQP2), in the renal collecting duct.
Andersen, D. +8 more
core +2 more sources
Aquaporin‐4 Overexpression in Rat ALS Model [PDF]
The Anatomical Record, 2008 AbstractOnset of motoneuron death characterizing amyotrophic lateral sclerosis (ALS) is closely linked to modified astrocytic and glial environments. Here, we show that in the spinal cord from transgenic rat overexpressing mutated human SOD1, aquaporin‐4 mRNA and protein are specifically overexpressed in the gray matter at end stage of disease ...
Nicaise, Charles +6 more
openaire +3 more sources
Mechanisms Underlying Aquaporin-4 Subcellular Mislocalization in Epilepsy
Frontiers in Cellular Neuroscience, 2022 Epilepsy is a chronic brain disorder characterized by unprovoked seizures. Mechanisms underlying seizure activity have been intensely investigated.
Jenny I. Szu, Devin K. Binder
doaj +1 more source
Volume changes during active shape fluctuations in cells [PDF]
, 2015 Cells modify their volume in response to changes in osmotic pressure but it is usually assumed that other active shape variations do not involve significant volume fluctuations.
Kardash, Elena +5 more
core +2 more sources
UNDULY ENHANCED RESPONSE TO TOLVAPTAN IN A WOMAN SHOWING SYNDROME OF INAPPROPRIATE ANTIDIURETIC HORMONE SECRETION: AN INVESTIGATION OF POSSIBLE CAUSES [PDF]
, 2017 Objective: To investigate possible causes of an excessive response to tolvaptan in a woman with syndrome of inappropriate antidiuretic hormone secretion (SIADH).
Lanzellotti, Davide +4 more
core +1 more source
Orthogonal array formation by human aquaporin-4: Examination of neuromyelitis optica-associated aquaporin-4 polymorphisms [PDF]
Journal of Neuroimmunology, 2011 Pathogenic autoantibodies target aquaporin-4 (AQP4) water channels in individuals with neuromyelitis optica (NMO). Recently, allelic mutations were reported at residue 19 of AQP4 in three cases of NMO, and it was suggested that polymorphisms may influence disease by altering AQP4 supramolecular assembly into orthogonal arrays of particles (OAPs).
Jonathan M, Crane +4 more
openaire +2 more sources
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Aquaporin 4: a player in cerebral edema and neuroinflammation
Journal of Neuroinflammation, 2012 Neuroinflammation is a common pathological event observed in many different brain diseases, frequently associated with blood brain barrier (BBB) dysfunction and followed by cerebral edema.
Fukuda Andrew M, Badaut Jerome
doaj +1 more source