Results 51 to 60 of about 11,586,786 (268)

Aquaporins in spinal cord injury: the janus face of aquaporin 4 [PDF]

Neuroscience, 2010
Although malfunction of spinal cord water channels (aquaporins, AQP) likely contributes to severe disturbances in ion/water homeostasis after spinal cord injury (SCI), their roles are still poorly understood. Here we report and discuss the potential significance of changes in the AQP4 expression in human SCI that generates glial fibrillary acidic ...
Taylor,, Olivera Nesic, Guest, J. D., Zivadinovic, D., Narayana, P. A., Herrera, J .J., Grill, R. J., Mokkapati, V. U.L, Gelman, B. B., Lee, J.   +8 more
openaire   +4 more sources

Diagnostic value of aquaporin-4-IgG live cell based assay in neuromyelitis optica spectrum disorders

Multiple sclerosis journal - experimental, translational and clinical, 2021
Objective Determine the utility of aquaporin 4 IgG (AQP4-IgG) testing (live cell-based assay) for Neuromyelitis Optica Spectrum Disorders (NMOSD). Methods We included Mayo Clinic patients (1/1/2018-12/31/2019) tested for serum AQP4-IgG by live cell-based
Vyanka Redenbaugh, Mayra Montalvo, E. Sechi, Marina Buciuc, J. Fryer, A. McKeon, V. Lennon, J. Mills, B. Weinshenker, D. Wingerchuk, John J. Chen, M. Tariq Bhatti, A. S. Lopez Chiriboga, S. Pittock, E. Flanagan   +14 more
semanticscholar   +1 more source

The physiological response of Populus tremula x alba leaves to the down-regulation of PIP1 aquaporin gene expression under no water stress. [PDF]

, 2013
In order to study the role of PIP1 aquaporins in leaf water and CO2 transport, several lines of PIP1-deficient transgenic Populus tremula x alba were generated using a reverse genetic approach. These transgenic lines displayed no visible developmental or
Secchi, Francesca, Zwieniecki, Maciej A
core   +3 more sources

Predictive Value of Serum Antibodies and Point Mutations of AQP4, AQP1 and MOG in A Cohort of Spanish Patients with Neuromyelitis Optica Spectrum Disorders [PDF]

, 2019
The detection of IgG aquaporin-4 antibodies in the serum of patients with Neuromyelitis optica (NMO) has dramatically improved the diagnosis of this disease and its distinction from multiple sclerosis.
Abril-Jaramillo, Javier, Casado Chocán, José Luis, Díaz Sánchez, María, Echevarría Irusta, Miriam, García Miranda, Pablo, García Sánchez, María Isabel, Lamas-Pérez, Lucía, Lebrato-Hernández, Lucía, Martínez Olivo, María del Mar, Morón Civanto, Francisco Jesús, Navarro, Gemma, Ramírez Lorca, Reposo, Romera, Mercedes, Suárez-Luna, Nela, Uclés Sánchez, Antonio José   +14 more
core   +1 more source

Neuromyelitis optica spectrum disorder with increased aquaporin-4 microparticles prior to autoantibodies in cerebrospinal fluid: a case report

Journal of Medical Case Reports, 2019
Background Neuromyelitis optica spectrum disorders are severe autoimmune inflammatory diseases of the central nervous system associated with the presence of immunoglobulin G antibodies against the water channel protein aquaporin-4.
Susanne Bejerot, Eva Hesselmark, Fariborz Mobarrez, Håkan Wallén, Max Albert Hietala, Rolf Nybom, Lennart Wetterberg   +6 more
doaj   +1 more source

Pathophysiologisch-serologische, bildgebende und klinische Charakteristika der Neuromyelitis Optica [PDF]

, 2019
Hintergrund: Neuromyelitis optica-Spektrum-Erkrankungen (NMOSD) stellen eine Gruppe neuroinflammatorischer Erkrankungen dar, die mit dem klinischen Auftreten von Myelitiden und/oder Optikusneuritiden (ON) einhergeht.
Schumacher, Sophie
core   +1 more source

Brainstem and cerebellar involvement in MOG-IgG-associated disorder versus aquaporin-4-IgG and MS

Journal of Neurology Neurosurgery & Psychiatry, 2020
Objective To determine the frequency and characteristics of brainstem or cerebellar involvement in myelin-oligodendrocyte-glycoprotein-antibody-associated-disorder (MOGAD) versus aquaporin-4-IgG-seropositive-neuromyelitis optica spectrum disorder (AQP4 ...
Samantha A. Banks, P. Morris, John Chen, S. Pittock, E. Sechi, Amy C. Kunchok, J. Tillema, J. Fryer, B. Weinshenker, K. Krecke, A. S. Lopez-Chiriboga, Adam Nguyen, T. Greenwood, C. Lucchinetti, Nicholas L. Zalewski, S. Messina, E. Flanagan   +16 more
semanticscholar   +1 more source

Aquaporin-4 expression in the human choroid plexus [PDF]

Cellular and Molecular Life Sciences, 2021
AbstractThe choroid plexus (CP) consists of specialized ependymal cells and underlying blood vessels and stroma producing the bulk of the cerebrospinal fluid (CSF). CP epithelial cells are considered the site of the internal blood-cerebrospinal fluid barrier, show epithelial characteristics (basal lamina, tight junctions), and express aquaporin-1 (AQP1)
Felix Deffner, Corinna Gleiser, Ulrich Mattheus, Andreas Wagner, Peter H Neckel, Petra Fallier-Becker, Bernhard Hirt, Andreas F Mack   +7 more
openaire   +4 more sources

Eculizumab in Aquaporin-4-Positive Neuromyelitis Optica Spectrum Disorder.

New England Journal of Medicine, 2019
BACKGROUND Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing, autoimmune, inflammatory disorder that typically affects the optic nerves and spinal cord.
S. Pittock, A. Berthele, K. Fujihara, H. Kim, M. Levy, Jacqueline Palace, I. Nakashima, M. Terzi, N. Totolyan, S. Viswanathan, Kai-Chen Wang, A. Pace, K. Fujita, R. Armstrong, D. Wingerchuk   +14 more
semanticscholar   +2 more sources

Increased intestinal carbonate precipitate abundance in the sea bream (Sparus aurata L.) in response to ocean acidification [PDF]

, 2019
Marine fish contribute to the carbon cycle by producing mineralized intestinal precipitates generated as by-products of their osmoregulation. Here we aimed at characterizing the control of epithelial bicarbonate secretion and intestinal precipitate ...
Carvalho, Edison S. M., Fuentes, Juan, Gregorio, Silvia, Ruiz-Jarabo, Ignacio   +3 more
core   +1 more source