Results 21 to 30 of about 20,290 (239)

NS1 Protein N-Linked Glycosylation Site Affects the Virulence and Pathogenesis of Dengue Virus

Vaccines, 2023
Live attenuated vaccine is one of the most effective vaccines against flavivirus. Recently, site-directed mutation of the flavivirus genome using reverse genetics techniques has been used for the rapid development of attenuated vaccines.
Enyue Fang, Miao Li, Xiaohui Liu, Kongxin Hu, Lijuan Liu, Zelun Zhang, Xingxing Li, Qinhua Peng, Yuhua Li   +8 more
doaj   +1 more source

Improved detection of genus-specific Alphavirus using a generic TaqMan® assay

BMC Microbiology, 2017
Background Alphaviruses are arthropod borne RNA viruses of medical importance. Geographical expansion of mosquitoes of the Aedes genus in the past decades has been associated with major Alphavirus-associated outbreaks. Climate changes and intensification
Claude Giry, Bénédicte Roquebert, Ghislaine Li-Pat-Yuen, Philippe Gasque, Marie-Christine Jaffar-Bandjee   +4 more
doaj   +1 more source

Broad Antiviral Activity of Ginkgolic Acid against Chikungunya, Mayaro, Una, and Zika Viruses

Viruses, 2020
The alphaviruses Chikungunya (CHIKV), Mayaro (MAYV), Una (UNAV), and the flavivirus Zika (ZIKV) are emerging or re-emerging arboviruses which are responsible for frequent epidemic outbreaks. Despite the large impact of these arboviruses on health systems,
Dalkiria Campos, Susana Navarro, Yessica Yadira Llamas-González, Madelaine Sugasti, José González-Santamaría   +4 more
doaj   +1 more source

Targeting Host PIM Protein Kinases Reduces Mayaro Virus Replication

Viruses, 2022
Mayaro virus (MAYV) manipulates cell machinery to successfully replicate. Thus, identifying host proteins implicated in MAYV replication represents an opportunity to discover potential antiviral targets.
Madelaine Sugasti-Salazar, Dalkiria Campos, Patricia Valdés-Torres, Paola Elaine Galán-Jurado, José González-Santamaría   +4 more
doaj   +1 more source

Trends of the Dengue Serotype-4 Circulation with Epidemiological, Phylogenetic, and Entomological Insights in Lao PDR between 2015 and 2019

Pathogens, 2020
Dengue outbreaks have regularly been recorded in Lao People’s Democratic Republic (PDR) since the first detection of the disease in 1979. In 2012, an integrated arbovirus surveillance network was set up in Lao PDR and an entomological surveillance has ...
Elodie Calvez, Virginie Pommelet, Somphavanh Somlor, Julien Pompon, Souksakhone Viengphouthong, Phaithong Bounmany, Thep Aksone Chindavong, Thonglakhone Xaybounsou, Phoyphaylinh Prasayasith, Sitsana Keosenhom, Paul T. Brey, Olivier Telle, Marc Choisy, Sébastien Marcombe, Marc Grandadam   +14 more
doaj   +1 more source

Inhibition of p38 Mitogen-Activated Protein Kinase Impairs Mayaro Virus Replication in Human Dermal Fibroblasts and HeLa Cells

Viruses, 2021
Mayaro virus (MAYV) hijacks the host’s cell machinery to effectively replicate. The mitogen-activated protein kinases (MAPKs) p38, JNK, and ERK1/2 have emerged as crucial cellular factors implicated in different stages of the viral cycle.
Madelaine Sugasti-Salazar, Yessica Y. Llamas-González, Dalkiria Campos, José González-Santamaría   +3 more
doaj   +1 more source

Neurocognitive impacts of arbovirus infections [PDF]

Journal of Neuroinflammation, 2020
AbstractArthropod-borne viruses or arbovirus, are most commonly associated with acute infections, resulting on various symptoms ranging from mild fever to more severe disorders such as hemorrhagic fever. Moreover, some arboviral infections can be associated with important neuroinflammation that can trigger neurological disorders including encephalitis,
Clé, Marion, Eldin, Patrick, Briant, Laurence, Lannuzel, Annie, Simonin, Yannick, van de Perre, Philippe, Cabié, André, Salinas, Sara   +7 more
openaire   +3 more sources

Circulation of Dirofilaria immitis and Dirofilaria repens in the Danube Delta Biosphere Reserve, Romania

Parasites & Vectors, 2018
Background Dirofilariosis is an emerging vector-borne parasitic disease in Europe. Monitoring of wild and domestic carnivores demonstrated circulation of Dirofilaria spp. in Romania in the past.
Alexandru Tomazatos, Daniel Cadar, Edina Török, Iulia Maranda, Cintia Horváth, Lujza Keresztes, Marina Spinu, Stephanie Jansen, Hanna Jöst, Jonas Schmidt-Chanasit, Egbert Tannich, Renke Lühken   +11 more
doaj   +1 more source

Unexpected high circulation of Plasmodium vivax in asymptomatic children from Kédougou, southeastern Senegal

Malaria Journal, 2017
Background Malaria in Senegal is due essentially to infections by Plasmodium falciparum and, to a lesser extent to Plasmodium malariae and Plasmodium ovale.
Makhtar Niang, Fode Diop, Oulimata Niang, Bacary D. Sadio, Abdourahmane Sow, Ousmane Faye, Mawlouth Diallo, Amadou A. Sall, Ronald Perraut, Aissatou Toure-Balde   +9 more
doaj   +1 more source

Molecular Epidemiology of Bluetongue Virus Serotype 9 in the Mediterranean Region

Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 2009
Resumen en inglès, ver archivo ...
K. Nomikou, S. Maan, N. S. Maan, P. P.C. Mertens   +3 more
doaj   +1 more source