Results 61 to 70 of about 3,562 (156)

Evaluation of a Luminex‐Based Multiplex Immunoassay of Hemorrhagic Fever Viruses in Senegal

open access: yesTransboundary and Emerging Diseases, Volume 2025, Issue 1, 2025.
Given the growing threat posed by viral hemorrhagic fevers, the development of surveillance tools is crucial to provide accurate and rapid solutions. Public health response involves risk assessment as well as effective and sustainable surveillance to ensure downstream communication and preparedness. A serological approach that offers high precision and
Safietou Sankhe   +17 more
wiley   +1 more source

Challenges Associated With Re‐Emergence of Lassa Fever in Nigeria: An Exploratory Study of Epidemiology, Phylogenomics, and Recommendations Toward Its Eradication

open access: yesHealth Science Reports, Volume 7, Issue 12, December 2024.
ABSTRACT Background Lassa fever (LF) is a viral hemorrhagic illness endemic in Nigeria and other West African countries. In recent years, the number of reported cases of LF in Nigeria has increased. In this study, we discussed the epidemiology of LF, the phylogenomics of the LF virus, issues associated with the increased cases of LF, and ...
Ridwan Olamilekan Adesola   +4 more
wiley   +1 more source

False positives complicate ancient pathogen identifications using high-throughput shotgun sequencing [PDF]

open access: yes, 2014
Background: Identification of historic pathogens is challenging since false positives and negatives are a serious risk. Environmental non-pathogenic contaminants are ubiquitous.
Campana, Michael G   +3 more
core   +3 more sources

Investigation of Viral, Bacterial and Parasitic Zoonotic Diseases in Rodents in Turkey

open access: yesVeterinary Medicine and Science, Volume 10, Issue 6, November 2024.
Rodents are reservoir hosts for zoonotic pathogens. In this study, the presence of viral lymphocytic choriomeningitis and hantavirus infections, bacterial tularaemia and leptospirosis, and parasitic leishmaniasis and toxoplasmosis were investigated in 498 rodents collected in Erzurum province, Turkey.
Mehmet Ozkan Timurkan   +5 more
wiley   +1 more source

Within host RNA virus persistence : mechanisms and consequences [PDF]

open access: yes, 2017
RER is funded by the Wellcome Trust, UK (Grant 101788/Z/13/Z) and DEG by US National Institutes of Health (R01 NS038932).In a prototypical response to an acute viral infection it would be expected that the adaptive immune response would eliminate all ...
Griffin, Diane E., Randall, Richard E.
core   +1 more source

Identification and Genetic Analysis of Species D Rotaviruses in Pangolin Samples

open access: yesTransboundary and Emerging Diseases, Volume 2024, Issue 1, 2024.
Pangolins have been found to carry severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2)‐related coronaviruses. In light of this discovery, interest has been piqued in viromes of these heavily trafficked wild animals. In this study, we performed viral metagenomic sequencing to explore viromes of both confiscated dead pangolins and captive ...
Kai Wang   +16 more
wiley   +1 more source

The Role of Platelets in Viral Hemorrhagic Fevers [PDF]

open access: yes, 2013
Arenaviridae, Bunyaviridae, Filoviridae and Flaviviridae are all RNA viruses that can induce a coagulopathy in infected patients. While there is a paucity of information on the cause of this coagulopathy, these viruses all produce a severe ...
Cox, Dermot   +2 more
core   +1 more source

Conserved Endonuclease Function of Hantavirus L Polymerase. [PDF]

open access: yes, 2016
Hantaviruses are important emerging pathogens belonging to the Bunyaviridae family. Like other segmented negative strand RNA viruses, the RNA-dependent RNA polymerase (RdRp) also known as L protein of hantaviruses lacks an intrinsic "capping activity ...
Engler, O.   +4 more
core   +2 more sources

Current state of diagnostics of pathogens of viral hemorrhagic fevers using isothermal amplification method

open access: yesСибирский научный медицинский журнал
The work is an overview of the loop-mediated isothermal amplification (LAMP) method and its application to diagnostics of hemorrhagic fevers. Its objective was to briefly characterize isothermal amplification and systematize the available data on ...
E. I. Krivosheina   +3 more
doaj   +1 more source

Uncoupling GP1 and GP2 expression in the Lassa virus glycoprotein complex: implications for GP1 ectodomain shedding [PDF]

open access: yes, 2008
Background Sera from convalescent Lassa fever patients often contains antibodies to Lassa virus (LASV) glycoprotein 1 (GP1), and glycoprotein 2 (GP2); Immunization of non-human primates with viral vectors expressing the arenaviral glycoprotein complex ...
Illick Kerry A   +7 more
core   +2 more sources

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