Results 81 to 90 of about 8,136 (194)

Preparedness of Emergency Room Nurses for Bioterrorism Based on the Health Belief Model: A Multicenter Qualitative Study

International Nursing Review, Volume 72, Issue 2, June 2025.
ABSTRACT Aim To explore emergency room nurses’ perceptions of preparedness for bioterrorism. Introduction In the context of evolving global security threats, including wars, terrorism, and emerging infectious diseases, it is critical to evaluate the bioterrorism response competencies of emergency room nurses and identify strategies to enhance their ...
Mi‐Kyeong Jeon, Yujeong Kim
wiley   +1 more source

Absence of an N-Linked Glycosylation Motif in the Glycoprotein of the Live-Attenuated Argentine Hemorrhagic Fever Vaccine, Candid #1, Results in Its Improper Processing, and Reduced Surface Expression [PDF]

, 2017
Junin virus (JUNV), a highly pathogenic New World arenavirus, is the causative agent of Argentine hemorrhagic fever (AHF). The live-attenuated Candid #1 (Can) strain currently serves as a vaccine for at-risk populations. We have previously shown that the
Alexey V. Seregin, Cheng Huang, John T. Manning, José Barral, Juan C. de la Torre, Nadezhda E. Yun, Slobodan Paessler, Takaaki Koma   +7 more
core   +1 more source

Therapeutic options for human papillomavirus‐positive tonsil and base of tongue cancer

Journal of Internal Medicine, Volume 297, Issue 6, Page 608-629, June 2025.
Abstract The incidences of human papillomavirus‐positive (HPV+) tonsillar and base tongue squamous cell carcinomas (TSCC and BOTSCC) have increased in recent decades. Notably, HPV+ TSCC and BOTSCC have a significantly better prognosis than their HPV‐negative counterparts when treated with current surgical options, radiotherapy, or intensified ...
Mark Zupancic, Ourania N. Kostopoulou, Linda Marklund, Tina Dalianis   +3 more
wiley   +1 more source

Silver Nanoparticle‐Mediated Antiviral Efficacy against Enveloped Viruses: A Comprehensive Review

Global Challenges, Volume 9, Issue 5, May 2025.
Silver nanoparticles (AgNPs) exhibit broad‐spectrum antiviral activity by targeting key viral structures and processes. They disrupt viral envelopes, compromising integrity, and bind to nucleocapsids, impairing viral replication. AgNPs also inhibit glycoprotein interactions, preventing viral attachment and entry into host cells.
Ekaterine Mosidze, Gianluigi Franci, Federica Dell'Annunziata, Nicoletta Capuano, Marica Colella, Flora Salzano, Massimiliano Galdiero, Aliosha Bakuridze, Veronica Folliero   +8 more
wiley   +1 more source

Replicating viral vector platform exploits alarmin signals for potent CD8⁺ T cell-mediated tumour immunotherapy. [PDF]

, 2017
Viral infections lead to alarmin release and elicit potent cytotoxic effector T lymphocyte (CTL ^eff ) responses. Conversely, the induction of protective tumour-specific CTL ^eff and their recruitment into the
A Hyvarinen, A Plyusnin, A Wortmann, AM Henao-Restrepo, C Baumann, C Butts, CA Klebanoff, CB Stephensen, D Peng, D Valmori, D Zamarin, DA Enria, DK Reichenbach, DL Popkin, E Scandella, ER Chare, F Duan, F Pages, F Spertini, GP Dunn, HE Webb, J Delaloye, J Liu, J Zhu, JA Joyce, JF Vansteenkiste, JY Liu, K Oboki, KM Quinn, L Flatz, L Flatz, L Flatz, L Zhang, LC Anton, M Lewandoski, M Peine, M Perez, M Suter, M Vanneman, MD Stenglein, MF Callan, MF Kotturi, MJ Townsend, N Fasnacht, O Kew, P Grob, P Sharma, PC Doherty, PC Tumeh, PW Kantoff, R Schirmbeck, R Sommerstein, RH Andtbacka, RM Zinkernagel, RM Zinkernagel, S Darbre, S Spranger, SA Fuertes Marraco, SA Rosenberg, SF Emonet, SG Hansen, SN Mueller, T Querec, TF Gajewski, TN Schumacher, WV Bonilla, WV Bonilla, X de Lamballerie, Y Iwai, Z Waibler   +69 more
core   +2 more sources

Population dynamic of porcine parvovirus indicates decrease of variability [PDF]

, 2013
Projeto/Plano de Ação: 02.11.10.600 ...
FOESTER, T., GAVA, D., HOMEIER, T., STRECK, A. F., TRUYEN, U.   +4 more
core  

The Lassa Virus Stable Signal Peptide Undergoes a Conformational Change to Aid Viral Fusion

Chemistry – A European Journal, Volume 31, Issue 18, March 25, 2025.
The unique stable signal peptide (SSP) of the Lassa virus glycoprotein complex undergoes a conformational change during pH‐dependent viral fusion. This revels a potential mechanism by which the enigmatic SSP influences the fusion process through interactions it makes with the fusion protein, glycoprotein 2 (GP2).
Shane D. Collins, Liqun Jiang, Yanxin Liu, Jinwoo Lee   +3 more
wiley   +1 more source

Visualization of Double-Stranded RNA Colocalizing With Pattern Recognition Receptors in Arenavirus Infected Cells

Frontiers in Cellular and Infection Microbiology, 2018
An important step in the initiation of the innate immune response to virus infection is the recognition of non-self, viral RNA, including double-stranded RNA (dsRNA), by cytoplasmic pattern recognition receptors (PRRs).
Elizabeth J. Mateer, Slobodan Paessler, Cheng Huang   +2 more
doaj   +1 more source

Innate and adaptive immune control of genetically engineered live-attenuated arenavirus vaccine prototypes [PDF]

, 2017
Arenaviruses such as Lassa virus (LASV) cause significant morbidity and mortality in endemic areas. Using a glycoprotein (GP) exchange strategy, we have recently developed live-attenuated arenavirus vaccine prototypes (rLCMV/VSVG) based on lymphocytic ...
Bergthaler, Andreas, Fernandez, Marylise, Flatz, Lukas, Horvath, Edit, Lutz, Hans, Pinschewer, Daniel D., Steinborn, Ralf, Suter, Mark   +7 more
core  

Two Birds With One Stone: RNA Virus Strategies to Manipulate G3BP1 and Other Stress Granule Components

WIREs RNA, Volume 16, Issue 2, March/April 2025.
Stress granules emerging during viral infection can play both pro‐ and antiviral roles. RNA viruses use various strategies to antagonize their formation, including the degradation, inhibition, or sequestration of G3BP1, a key stress granule protein. However, biochemical and structural insights into these mechanisms have been reported for only a handful
Moh Egy Rahman Firdaus, Eliana Dukhno, Rupali Kapoor, Piotr Gerlach   +3 more
wiley   +1 more source