Results 31 to 40 of about 8,104 (224)

Screening and Identification of Lujo Virus Inhibitors Using a Recombinant Reporter Virus Platform

Viruses, 2021
Lujo virus (LUJV), a highly pathogenic arenavirus, was first identified in 2008 in Zambia. To aid the identification of effective therapeutics for LUJV, we developed a recombinant reporter virus system, confirming reporter LUJV comparability with wild ...
Stephen R. Welch, Jessica R. Spengler, Sarah C. Genzer, Payel Chatterjee, Mike Flint, Éric Bergeron, Joel M. Montgomery, Stuart T. Nichol, César G. Albariño, Christina F. Spiropoulou   +9 more
doaj   +1 more source

Prevalence of inclusion body disease and associated comorbidity in captive collections of boid and pythonid snakes in Belgium [PDF]

, 2020
Inclusion body disease (IBD) is caused by reptarenaviruses and constitutes one of the most notorious viral diseases in snakes. Although central nervous system disease and various other clinical signs have been attributed to IBD in boid and pythonid ...
Hellebuyck, Tom, Leineweber, Christoph, Marschang, Rachel E, Simard, Jules   +3 more
core   +1 more source

Arenaviruses [PDF]

, 2007
The Arenaviridae family contains 22 recognized virus species, each of them strongly associated with a rodent species (except Tacaribe virus which is associated with a species of bat), suggesting an ancient co-evolutionary process. Although the concept of co-evolution between rodents and arenaviruses is now largely accepted, little has been uncovered in
Gonzalez, Jean-Paul, Emonet, Sébastien, De Lamballerie, Xavier, Charre, R.   +3 more
openaire   +3 more sources

Sphingosine Kinases Promote Ebola Virus Infection and Can Be Targeted to Inhibit Filoviruses, Coronaviruses, and Arenaviruses Using Late Endocytic Trafficking to Enter Cells

bioRxiv, 2022
Entry of enveloped viruses in host cells requires the fusion of the viral and host cell membranes, a process that is facilitated by viral fusion proteins protruding from the viral envelope.
Corina M Stewart, Yuxia Bo, K. Fu, M. Chan, R. Kozak, K. Y. Apperley, G. Laroche, Redaet Daniel, André M. Beauchemin, G. Kobinger, D. Kobasa, M. Côté   +11 more
semanticscholar   +1 more source

Genome Sequences of Five Arenaviruses from Pygmy Mice (Mus minutoides) in Sierra Leone

Microbiology Resource Announcements, 2022
The genome sequences of five strains of a mammarenavirus were assembled from metagenomic data from pygmy mice (Mus minutoides) captured in Sierra Leone.
Matej Vučak, J. Bangura, Bruno M. Ghersi, J. Nichols, J. Hughes, A. da Silva Filipe, A. Tremeau-Bravard, David J. Wolking, E. Amara, Abdulai A. Bangura, Marilyn C. Kanu, Osman T. Kanu, Dickson Kargbo, Edwin G. Lavalie, Victor Lungay, W. Robert, M. Turay, Steven Fornie, T. Samba, Bankolay B Sesay, P. Swaray, Mohamed A. Vandi, M. Bah, Andrew A Mansaray, B. Bird, A. Davison   +25 more
semanticscholar   +1 more source

Novel Arenavirus Isolates from Namaqua Rock Mice, Namibia, Southern Africa

Emerging Infectious Diseases, 2015
Arenaviruses are feared as agents that cause viral hemorrhagic fevers. We report the identification, isolation, and genetic characterization of 2 novel arenaviruses from Namaqua rock mice in Namibia.
Peter T. Witkowski, René Kallies, Julia Hoveka, Brita Auste, Ndapewa L. Ithete, Katarína Šoltys, Tomáš Szemes, Sung Sup Park, Wolfgang Preiser, Boris Klempa, John K.E. Mfune, Detlev H. Kruger   +11 more
doaj   +1 more source

Differential Disease Susceptibilities in Experimentally Reptarenavirus-Infected Boa Constrictors and Ball Pythons. [PDF]

, 2017
Inclusion body disease (IBD) is an infectious disease originally described in captive snakes. It has traditionally been diagnosed by the presence of large eosinophilic cytoplasmic inclusions and is associated with neurological, gastrointestinal, and ...
Boback, Scott M, DeRisi, Joseph L, Drazenovich, Tracy, Garcia, Valentina E, Hawkins, Michelle G, Hoon-Hanks, Laura L, Keel, M Kevin, Layton, Marylee L, Sanchez-Migallon Guzman, David, Stenglein, Mark D   +9 more
core   +1 more source

DDX3 suppresses type I interferons and favors viral replication during Arenavirus infection.

PLoS Pathogens, 2018
Several arenaviruses cause hemorrhagic fever (HF) diseases that are associated with high morbidity and mortality in humans. Accordingly, HF arenaviruses have been listed as top-priority emerging diseases for which countermeasures are urgently needed ...
María Eugenia Loureiro, Andre Luiz Zorzetto-Fernandes, Sheli Radoshitzky, Xiaoli Chi, Simone Dallari, Nuha Marooki, Psylvia Lèger, Sabrina Foscaldi, Vince Harjono, Sonia Sharma, Brian M Zid, Nora López, Nora López, Juan Carlos de la Torre, Sina Bavari, Elina Zúñiga   +15 more
doaj   +1 more source

Detection of arenavirus in a peripheral odontogenic fibromyxoma in a red tail boa (Boa constrictor constrictor) with inclusion body disease [PDF]

, 2015
A captive bred red tail boa (Boa constrictor constrictor) was presented with a large intraoral mass originating from the buccal gingiva, attached to the right dentary teeth row.
Ducatelle, Richard, Hellebuyck, Tom, Martel, An, Pasmans, Frank, Saey, Veronique   +4 more
core   +1 more source

Chapare virus, a newly discovered arenavirus isolated from a fatal hemorrhagic fever case in Bolivia. [PDF]

PLoS Pathogens, 2008
A small focus of hemorrhagic fever (HF) cases occurred near Cochabamba, Bolivia, in December 2003 and January 2004. Specimens were available from only one fatal case, which had a clinical course that included fever, headache, arthralgia, myalgia, and ...
Simon Delgado, Bobbie R Erickson, Roberto Agudo, Patrick J Blair, Efrain Vallejo, César G Albariño, Jorge Vargas, James A Comer, Pierre E Rollin, Thomas G Ksiazek, James G Olson, Stuart T Nichol   +11 more
doaj   +1 more source