Results 121 to 130 of about 181,531 (180)

N(6)-adenosine-methyltransferase-14 promotes glioma tumorigenesis by repressing argininosuccinate synthase 1 expression in an m6A-dependent manner.

Bioengineered, 2022
Miao YQ, Chen W, Zhou J, Shen Q, Sun Y, Li T, Wang SC.   +6 more
europepmc   +1 more source

The Role of Argininosuccinate Synthase Serine 328 Phosphorylation in Nitric Oxide Production

, 2012
Until recently, the main mechanism of argininosuccinate synthase (AS) regulation was described to exist mainly at the level of transcription. Transcriptional regulation of AS has been shown to be coordinate with eNOS in response to shear stress, hypoxia,
Haines, Ricci
core  

Keystone microbial isozyme enhances crustacean growth by utilizing L-citrulline

Microbiome
Background Under standardized rearing conditions, the genetically uniform “Keyong No. 1” swimming crab exhibits pronounced inter-individual variability in growth performance.
Weichuan Lin, Mingming Niu, Ye Sun, Wenkai Yu, Ronghua Li, Changkao Mu, Chunlin Wang, Limin Zhang, Jizhong Zhou, Yangfang Ye   +9 more
doaj   +1 more source

Reversed argininosuccinate lyase activity in fumarate hydratase-deficient cancer cells [PDF]

, 2013
Loss of function of fumarate hydratase (FH), the mitochondrial tumor suppressor and tricarboxylic acid (TCA) cycle enzyme, is associated with a highly malignant form of papillary and collecting duct renal cell cancer.
Frezza, Christian, Karim, Saadia A, Hedley, Ann, Gottlieb, Eyal, Blyth, Karen, Mackenzie, Elaine D, Watson, David G, Kalna, Gabriela, Zheng, Liang, Szlosarek, Peter   +9 more
core  

Invasive lobular carcinoma: integrated multi-omics analysis reveals silencing of Argininosuccinate synthase and upregulation of nucleotide biosynthesis in tamoxifen resistance. [PDF]

Cell Death Dis
Gupta A, Choueiry F, Reardon J, Pramod N, Kulkarni A, Shankar E, Sizemore ST, Stover DG, Zhu J, Ramaswamy B, Majumder S.   +10 more
europepmc   +1 more source

Oncogenic Kaposi's Sarcoma-Associated Herpesvirus Upregulates Argininosuccinate Synthase 1, a Rate-Limiting Enzyme of the Citrulline-Nitric Oxide Cycle, To Activate the STAT3 Pathway and Promote Growth Transformation. [PDF]

J Virol, 2019
Li T, Zhu Y, Cheng F, Lu C, Jung JU, Gao SJ.   +5 more
europepmc   +1 more source

Arginine metabolism in Saccharomyces cerevisiae: Subcellular localization of the enzymes

, 1978
Subcellular localization of enzymes of arginine metabolism in S. cerevisiae was studied by partial fractionation and stepwise homogenization of spheroplast lysates. These enzymes could clearly be divided into two groups.
Jauniaux, Jean Claude, Urrestarazu, Luis, Wiame, Jean-Marie   +2 more
core  

Argininosuccinate Synthase 1-Deficiency Enhances the Cell Sensitivity to Arginine through Decreased DEPTOR Expression in Endometrial Cancer. [PDF]

Sci Rep, 2017
Ohshima K, Nojima S, Tahara S, Kurashige M, Hori Y, Hagiwara K, Okuzaki D, Oki S, Wada N, Ikeda JI, Kanai Y, Morii E.   +11 more
europepmc   +1 more source

Metabolic Engineering of Pichia pastoris for S-Adenosylmethionine Overproduction via Transcriptomic-Guided Energy Reallocation. [PDF]

Biotechnol J
Shang YY, Li ZY, Wu JM, Yang H, Lian Z, Zhu HY, Qian JC, Xu F, Huang MZ.   +8 more
europepmc   +1 more source

Detection of homozygous genotypes for a putatively lethal recessive mutation in the porcine argininosuccinate synthase 1 (ASS1) gene

The sequencing of the pig genome revealed the existence of homozygous individuals for a nonsense mutation in the argininosuccinate synthase 1 (ASS1) gene (rs81212146, c.944T>A, L315X).
Quintanilla, Raquel, Amills i Eras, Marcel, Luigi Sierra, Maria Gracia, Mármol-Sánchez, Emilio   +3 more
core