Nitric oxide (NO) is synthesized from arginine by nitric oxide synthase (NOS), and citrulline which is generated can be recycled to arginine by argininosuccinate synthetase (AS) and argininosuccinate lyase (AL). Rats were injected with bacterial lipopolysaccharide (LPS), and expression of the inducible isoform of NOS (iNOS), AS, and AL was analyzed. In
A, Nagasaki +7 more
openaire +1 more source
A new assay for argininosuccinate in urine samples by high performance liquid chromatography
A rapid, sensitive and simple procedure has been developed for determination of argininosuccinate (ASA). The assay is based upon the enzymatic cleavage of ASA in the presence of excess of argininosuccinate lyase (ASAL), HPLC separation and UV-detection ...
GIRELLI, Anna Maria +4 more
core +1 more source
Integration of metabolite and transcript data of ornithine-linked pathways.
The squares indicate changes on both transcription and metabolic level in response to a CO2-shift from 400 ppm to 100 ppm (Student´s t-test ...
Miriam Laxa (6236678) +4 more
core +1 more source
Statement of Retraction: N(6)-adenosine-methyltransferase-14 promotes glioma tumorigenesis by repressing argininosuccinate synthase 1 expression in an m6A-dependent manner. [PDF]
europepmc +1 more source
Background Xylose from lignocellulose is one of the most abundant and important renewable and green raw materials. It is very important how to efficiently transform xylose into useful bioproducts such as fumaric acid and so on.
Peng Wang +6 more
doaj +1 more source
Argininosuccinate Synthase 1 links hepatic urea cycle to whole body lipid metabolism
Abstract The hepatic urea cycle is consistently suppressed in liver disease and hepatocellular carcinoma (HCC), but whether loss of individual enzymes contributes to disease initiation and progression remains unknown.
Kim, Laura C. +11 more
openaire +3 more sources
Endothelial Argininosuccinate Synthase mRNA 5′-Untranslated Region Diversity [PDF]
Laura C. Pendleton +4 more
openaire +1 more source
Arginine Depletion Therapy with ADI-PEG20 Limits Tumor Growth in Argininosuccinate Synthase-Deficient Ovarian Cancer, Including Small-Cell Carcinoma of the Ovary, Hypercalcemic Type. [PDF]
Ji JX +23 more
europepmc +1 more source
Argininosuccinate Synthase 1 (ASS1) Deficiency Promotes Fibroblast Activation and Pulmonary Fibrosis [PDF]
J.-M. Li +5 more
openaire +1 more source

