Results 101 to 110 of about 181,531 (180)
, 2012 Argininosuccinate synthase (ASS) is the rate-limiting enzyme in the urea cycle. Along with nitric oxide synthase (NOS)-2, ASS endows cells with the l-citrulline/nitric oxide (NO·) salvage pathway to continually supply l-arginine from l-citrulline for ...
Ward, Stephen C. +7 more
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Coinduction of Nitric Oxide Synthase, Argininosuccinate Synthetase, and Argininosuccinate Lyase in Lipopolysaccharide-treated Rats [PDF]
Journal of Biological Chemistry, 1996 Akitoshi Nagasaki +7 more
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, 2008 The citrulline-nitric oxide (NO) cycle, comprised of the enzymes argininosuccinate synthase (AS), argininosuccinate lyase (AL) and endothelial nitric oxide synthase (eNOS), is responsible for the regulated production of endothelial NO.
Corbin, Karen Davidowitz
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Crystallization and some properties of argininosuccinate synthase from rat liver [PDF]
FEBS Letters, 1975 Saheki, Takeyori +4 more
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Studies on nitric oxide (No), citrulline-no cycle enzmes, arginase, glutamine synthetase and oxidative status in anoxia (Hypobaric Hypoxia) and reperfusion states in rat brain [PDF]
, 2012 Nitric oxide is postulated to be involved in the pathophysiology of neurological disorders due to hypoxia/ anoxia in brain due to increased release of glutamate and activation ofNmethyl- D-aspartate receptors.
Mummedy, Swamy
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Cell Reports MedicineSummary: Natural killer (NK) cells exhibit impaired anti-tumor activity upon entering the tumor microenvironment (TME); however, the precise mechanism(s) remains elusive.
Rou Zhao +12 more
doaj +1 more source
The Trypanosoma brucei sphingolipid synthase, an essential enzyme and a drug target [PDF]
, 2009 Sphingolipids are important structural components of eukaryotic membranes, in addition they and their precursors are involved in signal transduction processes.
Pan, Ssu-Ying
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, 2016 In the urea cycle the “toxin” ammonium (NH4+) is converted to non-toxic urea by five consecutive enzymatic reactions in the liver. In hepatocytes, the rate-limiting, ATP-dependent enzyme carbamoyl phosphate synthetase 1 (CPS1), which is allosterically ...
Matthias Gautschi (2608306) +7 more
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Cell Death and DiseaseArgininosuccinate synthase (ASS1), a critical enzyme in the urea cycle, acts as a tumor suppressor in many cancers. To date, the anticancer mechanism of ASS1 has not been fully elucidated. Here, we found that phosphoglycerate dehydrogenase (PHGDH), a key
Wensong Luo +14 more
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Metabolite profile of benzoic acid biotransformation with hippuric acid as outcome.
, 2016 The metabolites of the primary biotransformation reactions are shown in red. Metabolites of metabolic reactions proposed as being associated with the biotransformation reactions are shown in black. [Metabolites shown in green are presumed to decrease due
Cindy Irwin (3373793) +5 more
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