Results 71 to 80 of about 181,531 (180)

Plant NAOGAT (ArgJ) Structure Reveals Mechanism of Ornithine Biosynthesis, Preference for Acetylornithine and Susceptibility to Mangotoxin

Plant, Cell &Environment, Volume 49, Issue 12, Page 10283-10300, December 2026.
ABSTRACT Arginine metabolism in plants is targeted by phytopathogens such as Pseudomonas syringae strains, which produce toxins that affect enzymes of plant arginine metabolism, causing devastating infections in crops. In this work, the structural and functional properties of plant N‐acetylornithine glutamate acetyltransferase (NAOGAT), the key ...
Maciej Nielipinski, Agnieszka J. Pietrzyk‐Brzezinska, Aleksandra Twarda‐Clapa, Bartosz Sekula   +3 more
wiley   +1 more source

Insulin Coordinately Regulates Nitric Oxide Synthase and Argininosuccinate Synthase to Maintain Vascular Endothelial Function

The FASEB Journal, 2010
The pathogenesis of diabetes includes impairment of vascular endothelial cell nitric oxide (NO) production. In this report, we demonstrate that insulin not only maintains endothelial NO production through regulation of endothelial nitric oxide synthase (eNOS), but also via the regulation of argininosuccinate ...
Laura C Pendleton, Ricci J Thompson, Karen D Corbin, Cynthia J Meininger, Duane C Eichler   +4 more
openaire   +1 more source

Protein levels of arginine-related enzymes in the STZ offspring kidney.

, 2013
(A) Representative western blots showing arginase II (Arg II, ∼40 kDa), cationic amino acid transporter-1 (CAT-1, ∼68 kDa), argininosuccinate synthase (ASS, ∼50 kDa), and argininosuccinate lysate (ASL, ∼50 kDa) bands.
Chien-Te Lee (280488), Chien-Ning Hsu (280485), Wei-Chia Lee (280486), You-Lin Tain (280484), Wen-Chin Lee (150376), Li-Tung Huang (280487), Ching-Yuang Lin (280489)   +6 more
core   +1 more source

Effects of dietary D-mannose supplementation on growth performance, intestinal digestive capacity, gut microbiota, and ammonia tolerance of largemouth bass Micropterus salmoides

Aquaculture Reports
To investigate the effects of D-mannose on the growth performance, intestinal digestion capacity, intestinal microbiota composition, and ammonia tolerance of largemouth bass, experiments were conducted using largemouth bass fry with an average body ...
Changyi Sun, Muzi Zhang, Dexiang Feng, Shidong Wang, Ming Li   +4 more
doaj   +1 more source

ASS1 Overexpression: A Hallmark of Sonic Hedgehog Hepatocellular Adenomas; Recommendations for Clinical Practice

Hepatology Communications, 2020
Until recently, 10% of hepatocellular adenomas (HCAs) remained unclassified (UHCA). Among the UHCAs, the sonic hedgehog HCA (shHCA) was defined by focal deletions that fuse the promoter of Inhibin beta E chain with GLI1.
Margaux Sala, Delphine Gonzales, Thierry Leste‐Lasserre, Nathalie Dugot‐Senant, Valérie Paradis, Sylvaine Di Tommaso, Jean‐William Dupuy, Vincent Pitard, Cyril Dourthe, Amedeo Sciarra, Christine Sempoux, Linda D. Ferrell, Andrew D. Clouston, Gregory Miller, Mathew M. Yeh, Swan Thung, Annette S.H. Gouw, Alberto Quaglia, Jing Han, Ji Huan, Cathy Fan, James Crawford, Yasuni Nakanuma, Kenichi Harada, Brigitte leBail, Claire Castain, Nora Frulio, Hervé Trillaud, Laurent Possenti, Jean‐Frédéric Blanc, Laurence Chiche, Christophe Laurent, Charles Balabaud, Paulette Bioulac‐Sage, Anne Aurélie Raymond, Frédéric Saltel   +35 more
doaj   +1 more source

Finding My Path: Listening, Learning, and Leading in Rare Disease: The 2025 Hower Award

Annals of the Child Neurology Society, EarlyView.
Andrea Gropman
wiley   +1 more source

Essential Oral Single Nutritional Therapy Products for Inherited Metabolic Diseases: Evidence and Consensus Assessment Using a Modified Delphi Method

Journal of Inherited Metabolic Disease, Volume 49, Issue 6, November 2026.
ABSTRACT Nutritional therapy is critical in managing inherited metabolic diseases (IMDs), and includes specialized diets and single nutritional therapy products (sNTPs) such as vitamins, cofactors, and amino acids. Many sNTPs function as medicines, but are regulated as food (e.g., food supplements), which can limit access, reimbursement, and consistent
Nina N. Stolwijk, Bart M. F. Penninx, Annet M. Bosch, Mirjam Langeveld, Gajja S. Salomons, Carla E. M. Hollak, Essential Nutritional Therapy Products for IMDs Consensus Group, Dorothea Möslinger, Saskia Wortmann, David Cassiman, Pavel Ješina, Jiri Zeman, Allan M. Lund, François Feillet, Nazi Tabatadze, Sarah C. Grünert, Anke Schumann, Ute Spiekerkoetter, Ulrike Mütze, Thomas Opladen, Anastasia Skouma, Ina Knerr, Serena Gasperini, Vincenza Gragnaniello, Mariarosa (Marina) Anna Beatrice Melone, Francesca Nardecchia, Alessandro La Rosa, Birutė Tumienė, Margreet Wagenmakers, Terry Derks, Camilla Tøndel, Beata Kieć‐Wilk, Urh Groselj, Amaya Bélanger‐Quintana, Javier De las Heras, Mireia del Toro Riera, Eva Venegas Moreno, Matthias Gautschi, Johannes Häberle, Elaine Murphy   +39 more
wiley   +1 more source

Integrated Transcriptomic and Metabolomic Analysis Elucidates the Impact of Acute Ammonia Stress on Carbohydrate and Lipid Metabolic Pathways in Yellow Catfish (Pelteobagrus fulvidraco)

Aquaculture Nutrition
Ammonia stress (AS) constitutes a significant environmental challenge that impedes aquaculture development. In this investigation, histomorphology assessments, physiological, and biochemical parameter analyses, and multiomics approaches were employed to ...
Xue Li, Shidong Wang, Muzi Zhang, Ming Li, Chao Chen   +4 more
doaj   +1 more source

Gene expression in the chicken caecum is dependent on microbiota composition

Veterinary Research, 2017
Gut microbiota is of considerable importance for each host. Despite this, germ-free animals can be obtained and raised to sexual maturity and consequences of the presence or absence of gut microbiota on gene expression of the host remain uncharacterised.
Jiri Volf, Ondrej Polansky, Zuzana Sekelova, Philippe Velge, Catherine Schouler, Bernd Kaspers, Ivan Rychlik   +6 more
doaj   +1 more source

Overview on ornithine synthesis and degradation.

, 2019
ADC1/2, arginine decarboxylase 1 and 2; ArgAH, arginine amidohydrolase; ASL, argininosuccinate lyase; ASSY, argininosuccinate synthetase; CARA, carbamoyl phosphate synthetase A; CARB, carbamoyl phosphate synthetase B; NAGS, N-acetyl-L-glutamate synthase;
Miriam Laxa (6236678), Marco Mühlenbruch (6236672), Christoph Peterhänsel (6236675), Christian Blume (6236666), Julia Ost (6236669)   +4 more
core   +1 more source