Results 111 to 120 of about 44,168 (193)

Loss of Argininosuccinate Synthetase-1 (ASS1) Occurs in Esophageal Adenocarcinoma and Represents a Promising Biomarker for Therapy with Pegargiminase. [PDF]

Cancers (Basel)
Knipper K, Lyu SI, Tzitzili E, Spielmann SM, Bruns CJ, Schmidt T, Popp FC, Quaas A.   +7 more
europepmc   +1 more source

High-throughput enrichment of temperature-sensitive argininosuccinate synthetase for two-stage citrulline production in E. coli.

Metab Eng, 2020
Schramm T, Lempp M, Beuter D, Sierra SG, Glatter T, Link H.   +5 more
europepmc   +1 more source

Reduced argininosuccinate synthetase expression in refractory sarcomas: Impacts on therapeutic potential and drug resistance. [PDF]

Oncotarget, 2016
Kim Y, Kobayashi E, Kubota D, Suehara Y, Mukaihara K, Akaike K, Ito A, Kaneko K, Chuman H, Kawai A, Kitano S.   +10 more
europepmc   +1 more source

The Combination of Arginine Deprivation and 5-Fluorouracil Improves Therapeutic Efficacy in Argininosuccinate Synthetase Negative Hepatocellular Carcinoma. [PDF]

Int J Mol Sci, 2017
Thongkum A, Wu C, Li YY, Wangpaichitr M, Navasumrit P, Parnlob V, Sricharunrat T, Bhudhisawasdi V, Ruchirawat M, Savaraj N.   +9 more
europepmc   +1 more source

Inactivation of argG, encoding argininosuccinate synthetase from Xanthomonas oryzae pv. oryzae, is involved in bacterial growth and virulence in planta

, 2009
Xanthomonas oryzae pv. oryzae (Xoo) is the causal pathogen of bacterial leaf blight disease. To screen components causing blight disease in rice, we mined genes containing a putative plant-inducible promoter (PIP) box in the promoter from a Xoo database ...
Byun, Myung Ok, Moon, Seok Jun, Ardales, Edna Y., Park, Sang Ryeol, Shin, Dongjin, Noh, Tae Hwan   +5 more
core  

Phase 1 Dose-Escalation Study of Pegylated Arginine Deiminase, Cisplatin, and Pemetrexed in Patients With Argininosuccinate Synthetase 1-Deficient Thoracic Cancers. [PDF]

J Clin Oncol, 2017
Beddowes E, Spicer J, Chan PY, Khadeir R, Corbacho JG, Repana D, Steele JP, Schmid P, Szyszko T, Cook G, Diaz M, Feng X, Johnston A, Thomson J, Sheaff M, Wu BW, Bomalaski J, Pacey S, Szlosarek PW.   +18 more
europepmc   +1 more source

Argininosuccinate synthetase regulates hepatic AMPK linking protein catabolism and ureagenesis to hepatic lipid metabolism. [PDF]

Proc Natl Acad Sci U S A, 2016
Madiraju AK, Alves T, Zhao X, Cline GW, Zhang D, Bhanot S, Samuel VT, Kibbey RG, Shulman GI.   +8 more
europepmc   +1 more source

Functional profiling of 2,193 ASS1 missense variants: Insights into variant pathogenicity and epistatic interactions in citrullinemia type I. [PDF]

PLoS Genet
Lo RS, Cromie GA, Tang M, Sirr A, Caldovic L, Morizono H, Ah Mew N, Gropman A, Dudley AM.   +8 more
europepmc   +1 more source

The arginine synthetase pathway is responsible for carbamoyl phosphate synthesis in <i>Thermococcus kodakarensis</i>. [PDF]

Front Microbiol
Michimori Y, Ohashi N, Szymanski C, Atomi H.   +3 more
europepmc   +1 more source

Impaired T cell function in argininosuccinate synthetase deficiency.

J Leukoc Biol, 2015
Tarasenko TN, Gomez-Rodriguez J, McGuire PJ.   +2 more
europepmc   +1 more source