Results 61 to 70 of about 44,168 (193)
ABSTRACT Arginine metabolism in plants is targeted by phytopathogens such as Pseudomonas syringae strains, which produce toxins that affect enzymes of plant arginine metabolism, causing devastating infections in crops. In this work, the structural and functional properties of plant N‐acetylornithine glutamate acetyltransferase (NAOGAT), the key ...
Maciej Nielipinski +3 more
wiley +1 more source
CPS1, carbamoyl phosphate synthetase 1; OTC, ornithine carbamoyltransferase; ASS1, argininosuccinate synthetase; ASL, argininosuccinate lyase; ARG1, arginase; GLUL, glutamate–ammonia ligase; ABD, antibody diluent (DAKO); PBS, Phosphate-buffered saline ...
Giora van Straten (580550) +10 more
core +1 more source
Overview on ornithine synthesis and degradation.
ADC1/2, arginine decarboxylase 1 and 2; ArgAH, arginine amidohydrolase; ASL, argininosuccinate lyase; ASSY, argininosuccinate synthetase; CARA, carbamoyl phosphate synthetase A; CARB, carbamoyl phosphate synthetase B; NAGS, N-acetyl-L-glutamate synthase;
Miriam Laxa (6236678) +4 more
core +1 more source
Finding My Path: Listening, Learning, and Leading in Rare Disease: The 2025 Hower Award
Annals of the Child Neurology Society, EarlyView.
Andrea Gropman
wiley +1 more source
This comprehensive review summarizes gastric cancer epidemiology, multifactorial risk factors (like infectious, dietary, genetic), pathogenesis such as precancerous evolution, molecular alterations, and a focus on the bidirectional interactions between gastric cancer cells and macrophages in the tumor microenvironment.
Yixuan Xin +6 more
wiley +1 more source
CPS1, carbamoyl phosphate synthetase 1; OTC, ornithine carbamoyltransferase; ASS1, argininosuccinate synthetase; ASL, argininosuccinate lyase; ARG1, arginase; NAGS, N-acetylglutamate synthase; GLUL, glutamate–ammonia ligase; GLUD1, glutamate ...
Giora van Straten (580550) +10 more
core +1 more source
Regulation of human argininosuccinate synthetase gene expression.
Expression of the human argininosuccinate synthetase (AS) gene is regulated in cultured cell lines. Expression of AS is repressed six-fold by growth of cells in the presence of arginine, while expression can be induced several hundred-fold by selection ...
Boyce, Frederick May, III
core +3 more sources
Phase 1 trial of ADI‐PEG 20 and liposomal doxorubicin in patients with metastatic solid tumors
Background Arginine depletion interferes with pyrimidine metabolism and DNA damage repair pathways. Preclinical data demonstrated that depletion of arginine by PEGylated arginine deiminase (ADI‐PEG 20) enhanced liposomal doxorubicin (PLD) cytotoxicity in
Shuyang Yao +10 more
doaj +1 more source
The nucleotide (nt) sequences of the genes encoding argininosuccinate synthetase synthetase from Escheria coli K-12 (argG) and Saccharomyces cerevisiae (ARG1) were determined.
Stalon, Victor +8 more
core +1 more source
Arginine deprivation therapy for malignant melanoma
Jung-Ki Yoon,1,2 Arthur E Frankel,3 Lynn G Feun,4 Suhendan Ekmekcioglu,1 Kevin B Kim11Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA; 2Hwasung Public Health Center, Hwasung, South ...
Yoon JK +4 more
doaj

