Results 61 to 70 of about 2,154,157 (294)

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Argumentation and Knowledge Construction in Higher Education: A Vygotskian Perspective

Praxis & Saber
Empirical research indicates that the utilization of argumentation as an educational strategy fosters the acquisition of argumentation skills and disciplinary knowledge.
Ingrid González-Palta, Antonia Larrain
doaj   +1 more source

Profile of The First Year Student’s Argumentation Skills on General Chemistry Courses at a Public University in West Sumatera: A Preliminary Study [PDF]

E3S Web of Conferences
Scientific argumentation is one of the key components of habits of mind, while habits of mind are one dimension of scientific literacy that should be developed in Indonesia.
Gazali Fauzana, Rahayu Sri, Munzil Munzil, Wonorahardjo Surjani   +3 more
doaj   +1 more source

Kemampuan Argumentasi Ilmiah Calon Guru IPA melalui Pendekatan MIKiR selama Pandemi Covid-19

Journal of Natural Science and Integration, 2021
Since the Covid-19 pandemic, learning at the university or school level has implemented online learning. Even though the learning is conducted online, the teacher candidate's scientific argumentation skills must be trained.
D Diniya, Aldeva Ilhami, Ira Mahartika, Niki Dian Permana P, Om Prakash   +4 more
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Diagnostic argumentation in teacher education: Making the case for justification, disconfirmation, and transparency

Frontiers in Education, 2022
Research on diagnosing in teacher education has primarily emphasized the accuracy of diagnostic judgments and has explained it in terms of factors such as diagnostic knowledge.
Elisabeth Bauer, Michael Sailer, Jan Kiesewetter, Martin R. Fischer, Frank Fischer   +4 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Facilitating argumentative knowledge construction with computer-supported collaboration scripts [PDF]

, 2007
Online discussions provide opportunities for learners to engage in argumentative debate, but learners rarely formulate well-grounded arguments or benefit individually from participating in online discussions.
Weinberger, Armin, Fischer, Frank, Stegmann, Karsten   +2 more
core   +1 more source

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

Evaluating Students' Argumentation Skills Using an Argument-Generating Learning Model Supported Toulmin’s Argumentation Pattern in Physics Concepts

Jurnal Pendidikan IPA Indonesia
This study examines the effectiveness of the Argument-Generating (AG) learning model, supported by Toulmin’s Argumentation Pattern, in enhancing students' argumentation skills with a specific focus on the topic of physics. The primary aim is to evaluate
Muslim Muslim, Rizky Agassy Sihombing, Rizki Zakwandi, Amir Karimi   +3 more
doaj   +1 more source