Results 81 to 90 of about 2,154,157 (294)
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
JPFT (Jurnal Pendidikan Fisika dan Teknologi)This study aims to analyze the profile of scientific argumentation skills of preservice physics teachers in the context of written case studies and oral presentations through video-based microteaching learning.
Gunawan Gunawan, Lovy Herayanti
doaj +1 more source
Teaching Argumentative Skills with LEGO
Metodo, 2023 When we want to enhance a skill, we obviously need to understand what that skill is. In this paper, I show that education’s typicalview of argumentative skill is based on the theory of cognitivism, a theory that claims that all cognition should be understood as an internal afair, asa process that takes place in the mind.
openaire +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Towards an authentic argumentation literacy test [Elektronisk resurs]
, 2023 A central goal of education is to improve argumentation literacy. How do we know how well this goal is achieved? Can we measure argumentation literacy?
Hietanen, Mika,, Rhetoric.
core
Enhancing Students’ Argumentation Skill Using an Argument Driven Inquiry-Based Module [PDF]
Journal of Education and Learning (EduLearn), 2018 Argumentation skills as a form of communication to externalize ideas through scientific discourse is a very important in learning of science. As an integral part of the science, argumentation skills should be integrated as a component of learning science.
Shinta Devi Amielia, Suciati, Maridi
openaire +2 more sources
Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology
Molecular Oncology, EarlyView.This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic +15 more
wiley +1 more source
Transparent Rational Decisions by Argumentation [PDF]
, 2013 There is a well-documented indication that several applications would benefit from the transparency afforded by argumentation to support decision-making where standard decision theory is not useful, e.g. in healthcare.
Craven, Robert +5 more
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An empirical study of argumentation schemes in deliberative dialogue [PDF]
, 2012 Collaborative decision making among agents in a team is a complex activity, and tasks to achieve individual objectives may conflict in a team context. A number of argumentation-based models have been proposed to address the problem, the rationale being ...
Sycara, Katia +5 more
core +1 more source
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source