Results 11 to 20 of about 644,370 (183)
Aromatase inhibitors in the treatment of endometriosis [PDF]
Menopause Review, 2016 Endometriosis is a chronic inflammatory condition in which foci of endometrial tissue grow outside of the uterine cavity. Endometriosis was estimated to affect 176 million women of childbearing potential all over the world in 2010.
Radosław Słopień +1 more
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Aromatase, aromatase inhibitors, and breast cancer [PDF]
Journal of Steroid Biochemistry and Molecular Biology, 2011 Estrogens are known to be important in the growth of breast cancers in both pre and postmenopausal women. As the number of breast cancer patients increases with age, the majority of breast cancer patients are postmenopausal women. Although estrogens are no longer made in the ovaries after menopause, peripheral tissues produce sufficient concentrations ...
Saranya Chumsri +2 more
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Aromatase inhibitors in the treatment of breast cancer in post-menopausal female patients: an update
Breast Cancer: Targets and Therapy, 2011 Reva Schneider1, Ayman Barakat1, John Pippen1,2,3, Cynthia Osborne1,2,3 1Medical Oncology, Baylor-Sammons Cancer Center, 2Texas Oncology PA, 3US Oncology, Dallas, TX, USA Abstract: Estrogen and its metabolites play a significant role in the proliferation
Schneider RE +3 more
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The effect of third-generation aromatase inhibitors on aromatase avtivity in visceral adipose tissue [PDF]
Regulatory Mechanisms in Biosystems, 2018 Pathogenesis and clinical manifestations of metabolic syndrome (and other conditions characterized by the growth of fat mass and decreased adiponectin content) is associated with an imbalance of sex hormones, which develops under the influence of ...
D. V. Lytkin +2 more
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Comparative study of the efficacy of tamoxifen and aromatase inhibitors among breast cancer patients at Kenyatta National Hospital [PDF]
Journal of the Egyptian National Cancer InstituteBackground Aromatase inhibitors have demonstrated superior outcomes compared to tamoxifen in various studies. However, research in Africa, including Kenya, where breast cancer mortality rates are disproportionately high, is lacking.
Henry Gachoki Macharia, Amsalu Degu
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Aromatase inhibitors in men: effects and therapeutic options [PDF]
Reproductive Biology and Endocrinology, 2011 Aromatase inhibitors effectively delay epiphysial maturation in boys and improve testosterone levels in adult men Therefore, aromatase inhibitors may be used to increase adult height in boys with gonadotropin-independent precocious puberty, idiopathic ...
de Jong Frank H, de Ronde Willem
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Drug Design, Development and Therapy, 2023 Panagiotis Peitsidis,1 Panagiotis Tsikouras,2 Antonio Simone Laganà,3 Alexandros Laios,4 Ioannis D Gkegkes,5 Christos Iavazzo6 1Department of Obstetrics and Gynecology Helena Venizelou Hospital, Athens, Greece; 2Department of Obstetrics and Gynecology ...
Peitsidis P +5 more
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Molecular Docking of Aromatase Inhibitors
Molecules, 2011 Aromatase is an enzyme that plays a critical role in the development of estrogen receptor positive breast cancer. As aromatase catalyzes the aromatization of androstenedione to estrone, a naturally occurring estrogen, it is a promising drug target for ...
Virapong Prachayasittikul +3 more
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Natural Inhibitors of the Aromatase Enzyme
Molecules, 2000 The results of three years of search for natural aromatase inhibitors will be presented.
Roberto R. Gil
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In Silico ADME Prediction and Molecular Docking of 1,2,3-Triazole-based Compounds Against Human Aromatase Cytochrome P450 [PDF]
Journal of Advanced Pharmacy Research, 2023 Objective: Inhibition of the human aromatase cytochrome P450 enzyme has been emphasized as being an efficient mechanism for reducing high estrogen levels in the treatment of breast cancer.
Ola Nosseir +5 more
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