Results 11 to 20 of about 51,507 (268)
This long‐term follow‐up study determined survival rates in a Swedish national cohort of 417 patients with breast cancer who all had neoadjuvant systemic therapy (NAST). Sentinel lymph node biopsy (SLNB) was performed before NAST in clinically node‐negative and after NAST in clinically node‐positive patients.
L. Zetterlund +4 more
wiley +1 more source
TRPA1 mediates aromatase inhibitor-evoked pain by the aromatase substrate androstenedione [PDF]
Aromatase inhibitors (AI) induce painful musculoskeletal symptoms (AIMSS), which are dependent upon the pain transducing receptor TRPA1. However, as the AI concentrations required to engage TRPA1 in mice are higher than those found in the plasma of ...
Benemei, Silvia +15 more
core +1 more source
Aromatase inhibitors in the treatment of endometriosis
Endometriosis is a chronic inflammatory condition in which foci of endometrial tissue grow outside of the uterine cavity. Endometriosis was estimated to affect 176 million women of childbearing potential all over the world in 2010.
Radosław Słopień +1 more
doaj +1 more source
Aromatase inhibitors in male: A literature review
Aromatase (CYP19A1) is a monooxygenase from the family of cytochrome P450 that plays role in the androgens to estrogens conversion. Aromatase inhibitors prohibit the aromatase enzyme function.
Mohsen Korani
doaj +1 more source
Treatment of Girls and Boys with McCune-Albright Syndrome with Precocious Puberty - Update 2017 [PDF]
The most common endocrinopathy associated with McCune-Albright Syndrome (MAS) is peripheral precocious puberty (PP) which occurs far more often in girls than in boys.
Eugster, Erica A., Neyman, Anna
core +1 more source
Aromatase inhibitors in men: effects and therapeutic options
Aromatase inhibitors effectively delay epiphysial maturation in boys and improve testosterone levels in adult men Therefore, aromatase inhibitors may be used to increase adult height in boys with gonadotropin-independent precocious puberty, idiopathic ...
de Jong Frank H, de Ronde Willem
doaj +1 more source
Sex-dependent influence of endogenous estrogen in pulmonary hypertension [PDF]
Rationale: The incidence of pulmonary arterial hypertension (PAH) is greater in women suggesting estrogens may play a role in the disease pathogenesis. Experimentally, in males exogenously administered estrogen can protect against PH; however in models ...
Audrey F. Wright +17 more
core +1 more source
Adherence to adjuvant therapy in post-menopausal breast cancer patients: A review [PDF]
This is the post-print version of the Article. The official published version can be accessed from the link below - Copyright @ 2012 John Wiley & Sons, IncThis review aimed to address the concept of adherence to adjuvant therapy in post-menopausal women.
Banning, M
core +1 more source
Immunolocalization of steroidogenic enzymes in the vaginal mucous of Galea spixii during the estrous cycle. [PDF]
BackgroundThe synthesis of sex steroids is controlled by several enzymes such as17α-hydroxylase cytochrome P450 (P450c17) catalyzing androgen synthesis and aromatase cytochrome P450 (P450arom) catalyzing estrogen synthesis, both of which must complex ...
Assis Neto, Antônio Chaves de +5 more
core +1 more source
Preventative therapies for healthy women at high risk of breast cancer [PDF]
Licensed under the Creative Commons Attribution Non-Commercial ...
Sestak, I
core +3 more sources

