Results 31 to 40 of about 45,700 (234)

Arrestin-Coding Genes Regulate Endocytosis, Sporulation, Pathogenicity, and Stress Resistance in Arthrobotrys oligospora

Frontiers in Cellular and Infection Microbiology, 2022
Arrestins are a family of scaffold proteins that play a crucial role in regulating numerous cellular processes, such as GPCR signaling. The Arthrobotrys oligospora arrestin family contains 12 members, which have highly conserved N-terminal and C-terminal
Liang Zhou, Liang Zhou, Mengfei Li, Mengfei Li, Peijie Cui, Peijie Cui, Mengqing Tian, Mengqing Tian, Ya Xu, Ya Xu, Xi Zheng, Xi Zheng, Keqin Zhang, Keqin Zhang, Guohong Li, Guohong Li, Xin Wang, Xin Wang   +17 more
doaj   +1 more source

Novel Electrophilic and Photoaffinity Covalent Probes for Mapping the Cannabinoid 1 Receptor Allosteric Site(s) [PDF]

, 2015
ACKNOWLEDGMENTS The work was supported by National Institutes of Health grants DA027113 and EY024717 to G.A.T. and DA09158 to A.M. A portion of this work was submitted in 2011 by A. Kulkarni in partial fulfillment of M.S.
Cascio, Maria G., Denovan-Wright, Eileen M., Janero, David R., Korde, Anisha, Kulkarni, Abhijit R., Kulkarni, Pushkar M., Laprairie, Robert B., Makriyannis, Alexandros, Pertwee, Roger G., Thakur, Ganesh A., Tichkule, Ritesh B., Zhou, Han, Zvonok, Nikolai   +12 more
core   +3 more sources

Cannabinoid CB1 and CB2 Receptor-Mediated Arrestin Translocation: Species, Subtype, and Agonist-Dependence

Frontiers in Pharmacology, 2019
Arrestin translocation and signaling have come to the fore of the G protein-coupled receptor molecular pharmacology field. Some receptor–arrestin interactions are relatively well understood and considered responsible for specific therapeutic or adverse ...
Mikkel Søes Ibsen, Mikkel Søes Ibsen, David B. Finlay, Monica Patel, Monica Patel, Jonathan A. Javitch, Jonathan A. Javitch, Michelle Glass, Natasha Lillia Grimsey, Natasha Lillia Grimsey   +9 more
doaj   +1 more source

QR code model: a new possibility for GPCR phosphorylation recognition

Cell Communication and Signaling, 2022
G protein-coupled receptors (GPCRs) are the largest family of membrane proteins in the human body and are responsible for accurately transmitting extracellular information to cells. Arrestin is an important member of the GPCR signaling pathway.
Hao Chen, Suli Zhang, Xi Zhang, Huirong Liu   +3 more
doaj   +1 more source

Functional characterization of an arrestin gene on insecticide resistance of Culex pipiens pallens

Parasites & Vectors, 2012
Background Continuous and excessive application of insecticides has resulted in the rapid development of insecticide resistance in several mosquito species, including Culex pipiens pallens.
Sun Yan, Zou Ping, Yu Xin-You, Chen Chen, Yu Jing, Shi Lin-Na, Hong Shan-Chao, Zhou Dan, Chang Xue-Lian, Wang Wei-Jie, Shen Bo, Zhang Dong-Hui, Ma Lei, Zhu Chang-Liang   +13 more
doaj   +1 more source

Development of indole sulfonamides as cannabinoid receptor negative allosteric modulators [PDF]

, 2016
This Letter was supported by the Biotechnology and Biological Sciences Research Council (BBSRC) and the Scottish Universities Life Sciences Alliance (SULSA) in 2011Peer ...
Abdelrahman, Mostafa Hamed, Baillie, Gemma L., Greig, Iain R., Ross, Ruth A., Trembleau, Laurent   +4 more
core   +1 more source

G Protein-Coupled Receptor Kinase 2 Selectively Enhances β-Arrestin Recruitment to the D₂ Dopamine Receptor through Mechanisms That Are Independent of Receptor Phosphorylation

Biomolecules, 2023
The D2 dopamine receptor (D2R) signals through both G proteins and β-arrestins to regulate important physiological processes, such as movement, reward circuitry, emotion, and cognition.
Marta Sánchez-Soto, Noelia M. Boldizsar, Kayla A. Schardien, Nora S. Madaras, Blair K. A. Willette, Laura R. Inbody, Christopher Dasaro, Amy E. Moritz, Julia Drube, Raphael S. Haider, R. Benjamin Free, Carsten Hoffman, David R. Sibley   +12 more
doaj   +1 more source

Cognitive impairment induced by delta9-tetrahydrocannabinol occurs through heteromers between cannabinoid CB1 and serotonin 5-HT2A receptors [PDF]

, 2015
Delta-9-tetrahydrocannabinol (THC), the main psychoactive compound of marijuana, induces numerous undesirable effects, including memory impairments, anxiety, and dependence.
A Busquets-Garcia, A Castañé, A Kern, A Manglik, A Pazos, A Pertovaara, A Zimmer, AC Magalhaes, AJ Venkatakrishnan, AL Bodor, Antoni Pastor, AR Best, Arnau Cordomí, BB Gorzalka, C Bombardi, C Castellano, C Ferrada, C Sanchis-Segura, Carmen Lluís, CP Vandermaelen, E Aso, E Fiorica-Howells, E Moreno, E Moreno, E Moreno, E Palazzo, E Puighermanal, E Puighermanal, E Valjent, Enric I. Canela, Eric J. Nestler, Estefanía Moreno, ET Weber, F Berrendero, F Rodríguez de Fonseca, F Simonin, F Steindel, FA Moreira, G Di Chiara, G Mengod, G Paxinos, G Porras, G Soria, Gemma Navarro, GM Thomas, HY Meltzer, J De Almeida, J González-Maeso, J González-Maeso, JC Parrish, JF Cheer, JF López-Giménez, JF López-Giménez, JJ Rodriguez, JM Franklin, JM Walker, JR Clapper, K Baba, K Mackie, K Monory, K Tsou, K Tsou, KA Gleason, L a. H Miner, L Callén, L Lanfumey, Laurence Lanfumey, Leonardo Pardo, Lesley A. Howell, LJ Sim-Selley, LP Martin, LTO Lee, M Bouvier, M Fribourg, M Lüttgen, M Schneider, M-M Mocanu, MJ Orejarena, N Kabli, NA Darmani, NB Eddy, NV Weisstaub, O Söderberg, P Pacher, P Rivera, Paola Gasperini, Patricia Robledo, Peter J. McCormick, R Franco, R Maldonado, R Mechoulam, R Mongeau, R Nygaard, R Schroder, Rafael de La Torre, Rafael Maldonado, RL Jakab, S Ferre, S Ferré, S Ferré, S González, S Haj-Dahmane, S Mato, S Pellow, SGF Rasmussen, SGF Rasmussen, SM Eggan, T Issad, T-W Chen, V Mendizábal, X Guitart, Xavier Viñals, Y-C Chiang   +112 more
core   +6 more sources

SnapShot: β-Arrestin Functions

Cell, 2020
The arrestins are ubiquitously expressed adaptor proteins that orchestrate transmembrane signaling cascades triggered by the 7-transmembrane G protein-coupled receptors. While originally discovered as proteins that block receptor-G protein coupling, arrestins are now appreciated for their expanding repertoire of dynamic protein interactions and ...
Seungkirl, Ahn, Sudha K, Shenoy, Louis M, Luttrell, Robert J, Lefkowitz   +3 more
openaire   +2 more sources

X‐Arrestin: a new retinal arrestin mapping to the X chromosome [PDF]

FEBS Letters, 1993
We have been using a differential cDNA cloning approach to isolate human retina‐specific and retina‐enriched genes [1]. A 1,314 bp cDNA was isolated by this approach, representing a highly retina‐specific message encoding a 388 amino acid protein showing 58%, 50%, and 49% homology to bovine β‐arrestin, and bovine and human retinal arrestin (S‐antigen),
Murakami, Akira, Yajima, Toshihiro, Sakuma, Hitoshi, McLaren, Margaret J., Inana, George   +4 more
openaire   +2 more sources