Results 11 to 20 of about 24,588 (216)
Distinct membrane binding properties of the two non-visual arrestins [PDF]
Communications BiologyMembrane interactions play a crucial role in regulating arrestin activation and its binding to phosphorylated G protein-coupled receptors (GPCRs).
Thomas D. Killeen +11 more
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Arrestin development: a role for β-arrestins in viral myocarditis [PDF]
American Journal of Physiology-Heart and Circulatory PhysiologyShaoni Dasgupta +2 more
openaire +3 more sources
Targeted disruption of β-arrestin 2-mediated signaling pathways by aptamer chimeras leads to inhibition of leukemic cell growth. [PDF]
PLoS ONE, 2014 β-arrestins, ubiquitous cellular scaffolding proteins that act as signaling mediators of numerous critical cellular pathways, are attractive therapeutic targets because they promote tumorigenesis in several tumor models.
Jonathan W Kotula +7 more
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Frontiers in Oncology, 2023 Hormones may be key factors driving cancer development, and epidemiological findings suggest that steroid hormones play a crucial role in ovarian tumorigenesis.
Ji-Won Ryu +12 more
doaj +1 more source
The effect of arrestin conformation on the recruitment of c-Raf1, MEK1, and ERK1/2 activation.
PLoS ONE, 2011 Arrestins are multifunctional signaling adaptors originally discovered as proteins that "arrest" G protein activation by G protein-coupled receptors (GPCRs).
Sergio Coffa +6 more
doaj +1 more source
FYVE-dependent endosomal targeting of an arrestin-related protein in amoeba. [PDF]
PLoS ONE, 2010 BACKGROUND: Visual and β-arrestins are scaffolding proteins involved in the regulation of receptor-dependent intracellular signaling and their trafficking.
Dorian Guetta +4 more
doaj +1 more source
The Effects of Apelin and Elabela Ligands on Apelin Receptor Distinct Signaling Profiles
Frontiers in Pharmacology, 2021 Apelin and Elabela are endogenous peptide ligands for Apelin receptor (APJ), a widely expressed G protein-coupled receptor. They constitute a spatiotemporal dual ligand system to control APJ signal transduction and function.
Yunlu Jiang +11 more
doaj +1 more source
Letter to the Editor: LO2, a misidentified cell line: Some data should be interpreted with caution
, 2022 Hepatology, EarlyView.
Ralf Weiskirchen
wiley +1 more source
X‐Arrestin: a new retinal arrestin mapping to the X chromosome [PDF]
FEBS Letters, 1993 We have been using a differential cDNA cloning approach to isolate human retina‐specific and retina‐enriched genes [1]. A 1,314 bp cDNA was isolated by this approach, representing a highly retina‐specific message encoding a 388 amino acid protein showing 58%, 50%, and 49% homology to bovine β‐arrestin, and bovine and human retinal arrestin (S‐antigen),
Murakami, Akira +4 more
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Frontiers in Endocrinology, 2020 Establishing reliable prognostic factors as well as specific targets for new therapeutic approaches is an urgent requirement in advanced ovarian cancer. For several tumor entities, the ubiquitously spread scaffold protein β-arrestin 2, a multifunctional ...
Bastian Czogalla +17 more
doaj +1 more source