Results 11 to 20 of about 24,311 (208)
Letter to the Editor: LO2, a misidentified cell line: Some data should be interpreted with caution
, 2022 Hepatology, EarlyView.
Ralf Weiskirchen
wiley +1 more source
β-arrestin functionally regulates the non-bleaching pigment parapinopsin in lamprey pineal. [PDF]
PLoS ONE, 2011 The light response of vertebrate visual cells is achieved by light-sensing proteins such as opsin-based pigments as well as signal transduction proteins, including visual arrestin.
Emi Kawano-Yamashita +5 more
doaj +1 more source
Targeted disruption of β-arrestin 2-mediated signaling pathways by aptamer chimeras leads to inhibition of leukemic cell growth. [PDF]
PLoS ONE, 2014 β-arrestins, ubiquitous cellular scaffolding proteins that act as signaling mediators of numerous critical cellular pathways, are attractive therapeutic targets because they promote tumorigenesis in several tumor models.
Jonathan W Kotula +7 more
doaj +1 more source
Frontiers in Oncology, 2023 Hormones may be key factors driving cancer development, and epidemiological findings suggest that steroid hormones play a crucial role in ovarian tumorigenesis.
Ji-Won Ryu +12 more
doaj +1 more source
The effect of arrestin conformation on the recruitment of c-Raf1, MEK1, and ERK1/2 activation.
PLoS ONE, 2011 Arrestins are multifunctional signaling adaptors originally discovered as proteins that "arrest" G protein activation by G protein-coupled receptors (GPCRs).
Sergio Coffa +6 more
doaj +1 more source
FYVE-dependent endosomal targeting of an arrestin-related protein in amoeba. [PDF]
PLoS ONE, 2010 BACKGROUND: Visual and β-arrestins are scaffolding proteins involved in the regulation of receptor-dependent intracellular signaling and their trafficking.
Dorian Guetta +4 more
doaj +1 more source
DEER Analysis of GPCR Conformational Heterogeneity
Biomolecules, 2021 G protein-coupled receptors (GPCRs) represent a large class of transmembrane helical proteins which are involved in numerous physiological signaling pathways and therefore represent crucial pharmacological targets.
Matthias Elgeti, Wayne L. Hubbell
doaj +1 more source
β-Arrestin-Mediated Signaling Improves the Efficacy of Therapeutics
Journal of Pharmacological Sciences, 2012 β-Arrestins (β-arrestin-1 and β-arrestin-2) were first identified as proteins that have the ability to desensitize G protein-coupled receptors (GPCRs). However, it has recently been found that β-arrestins can activate signaling pathways independent of G ...
Islam A.A.E.-H. Ibrahim, Hitoshi Kurose
doaj +1 more source
Frontiers in Cellular and Infection Microbiology, 2022 Arrestins are a family of scaffold proteins that play a crucial role in regulating numerous cellular processes, such as GPCR signaling. The Arthrobotrys oligospora arrestin family contains 12 members, which have highly conserved N-terminal and C-terminal
Liang Zhou +17 more
doaj +1 more source
X‐Arrestin: a new retinal arrestin mapping to the X chromosome [PDF]
FEBS Letters, 1993 We have been using a differential cDNA cloning approach to isolate human retina‐specific and retina‐enriched genes [1]. A 1,314 bp cDNA was isolated by this approach, representing a highly retina‐specific message encoding a 388 amino acid protein showing 58%, 50%, and 49% homology to bovine β‐arrestin, and bovine and human retinal arrestin (S‐antigen),
Murakami, Akira +4 more
openaire +2 more sources