Results 111 to 120 of about 7,439 (222)

The Role of N6‐Methyladenosine Modification in Health and Disease

MedComm, Volume 7, Issue 6, June 2026.
N6‐methyladenosine (m6A) is the most prevalent internal RNA modification in eukaryotes, acting as a pivotal epitranscriptomic regulator of RNA metabolism. This modification plays a dual role: it maintains physiological homeostasis under normal conditions but drives disease progression when dysregulated.
Linghuan Li, Yuanhai Sun, Wanfang Zheng, Lingqin Li, Yaqian Feng, Minyou Qi, Hanbing Li   +6 more
wiley   +1 more source

Bacillus secretes nucleases to degrade dsRNA, thereby reducing host's susceptibility to RNAi. [PDF]

NPJ Biofilms Microbiomes
Han X, Li H, Xu S, Miao X, Guan R.
europepmc   +1 more source

Acute Lung Injury: From Molecular Circuits to System‐Level Therapeutics

MedComm, Volume 7, Issue 6, June 2026.
This visual summary illustrates the paradigm shift from linear pathways to network medicine in ALI. Three interconnected circuits—innate immunity, immunometabolism, and cell death (PANoptosis)—drive disease progression under multiorgan crosstalk (gut–lung, brain–lung).
Yaoli Hou, Sheng He, Lili He, Kun Liu, Wen Tang, Deming Wang, Jing Gui, Zhiying Zeng, Yan Wang, Wenjie Liu, Ren Jing   +10 more
wiley   +1 more source

Antifungal activity of the culture filtrate of <i>Chaetomium subaffine</i> LB-1 against <i>Bipolaris maydis</i> and its underlying interaction mechanism. [PDF]

Front Microbiol
Liu C, Zhao Z, Chang Z.
europepmc   +1 more source

Gene‐specific double‐stranded RNAs induce mortality in the South African mealybug Delottococcus aberiae

Pest Management Science, Volume 82, Issue 6, Page 5184-5194, June 2026.
Gene‐specific double‐stranded RNAs effectively silence essential genes in the invasive citrus pest Delottococcus aberiae, leading to significant mortality through both microinjection and oral delivery. These results provide proof of concept for RNA interference‐based biopesticides as selective and sustainable tools for citrus integrated pest management.
Carolina Gallego‐Giraldo, Alberto Urbaneja, Omar Ruíz‐Rivero, Verónica Aragonés, Marie Guijarro‐Guijarro, José‐Antonio Daròs, Meritxell Perez‐Hedo   +6 more
wiley   +1 more source

A rapidly labelled RNA associated with DNA in HeLa cells

, 1967
The nucleic acids of HeLa cells, labelled for 30 min with [3H]uridine are extracted by sodium dodecylsulphate-chloroform-isoamylalcohol and fractionated on methylated bovine serum albumin adsorbed on kieselguhr (MAK) columns and by Cs2SO4 density ...
Levis, Angelo Gino, Krsmanovic, Velibor, Errera, Maurice Leo   +2 more
core  

Opening new frontiers with catalytic nucleic acids in miRNA inhibition. [PDF]

Front Pharmacol
Patutina O, Miroshnichenko S, Chiglintseva D, Zenkova M.   +3 more
europepmc   +1 more source

Identification of resistance sources and genomic regions regulating spot blotch resistance in Asian bread wheat (Triticum aestivum L.) via genome‐wide association study

The Plant Genome, Volume 19, Issue 2, June 2026.
Abstract Spot blotch (SB), caused by Bipolaris sorokiniana, is a major yield‐limiting disease of wheat (Triticum aestivum L.) in the warm, humid agroclimatic zones of South Asia. The development of resistant cultivars through molecular approaches offers a sustainable strategy for managing this disease.
Nikita Aggarwal, Xinyao He, Mukesh Rathore, Farkhandah Jan, Vikas Gupta, Reyazul Rouf Mir, Pawan K. Singh   +6 more
wiley   +1 more source

peptide nucleic acid‐based artificial ribonuclease

, 2020

core   +1 more source

Studies on phosphate ester cleavage and development of oligonucleotide based artificial nucleases (OBAN’s)

, 2004
Five different Oligonucleotide Based Artificial Nuclease (OBAN) systems have been synthesized. OBAN's may be regarded as a development of traditional antisense methodology where inhibition of gene expression can be achieved by hybridizing a synthetic ...
Hans Åström (2702254)
core