Results 111 to 120 of about 1,485,663 (260)

Whole‐Genome Sequencing and Resequencing of Hucho bleekeri Provides Insights into Genetic Mechanisms of Environmental Adaptation

Integrative Zoology, EarlyView.
A high‐quality chromosome‐level reference genome was constructed for Hucho bleekeri. Population structure and environmental adaptation of Hucho species were revealed by whole‐genome resequencing. ABSTRACT Salmonidae represents an important family in the study of genome evolution following genome duplication.
Yeyu Chen, Huanchao Yang, Zhao Liu, Xiaoyun Wu, Qinyao Wei, Yanling Chen, Jue Lin, Yi Yu, Quanyu Tu, Hua Li   +9 more
wiley   +1 more source

Urinary ribonuclease excretion in pancreatic disease.

, 1983
Urinary ribonuclease output and indices of renal tubular integrity were evaluated in control subjects and patients with pancreatic cancer, chronic pancreatitis and extrapancreatic diseases.
FABRIS C., VIANELLO, DANIELA, PICCOLI, ANTONIO, DEL FAVERO G., MEANI A., NACCARATO R., BONVICINI P., FARINI R., BROSOLO P.   +8 more
core  

Enhanced fish detection sensitivity in aquatic systems using environmental RNA

Methods in Ecology and Evolution, EarlyView.
Abstract Environmental RNA (eRNA) can potentially augment the biological monitoring ability of the established environmental DNA (eDNA) application in conservation. Despite faster degradation, environmental RNA could offer unique advantages: it may help reduce the legacy signal compared to eDNA, provide insights into physiological status through gene ...
Ana Ramón‐Laca, Ramón Gallego, Carmen Duque, José L. J. Ledesma, Ignacio Doadrio, Kim M. Parsons, Krista M. Nichols, Samantha Engster, Abigail Wells, Ana Riesgo   +9 more
wiley   +1 more source

Cyclen-based lanthanide complexes as ribonuclease mimics

, 2004
THESIS 7479This thesis, entitled "Novel Cyclen-based Lanthanide Complexes as Ribonuclease Mimics" is divided into six chapters. Chapter One introduces the field of mRNA cleavage, with emphasis on the hydrolysis of phosphodiesters.
Mulready, Sinead
core  

Effect of Abrocitinib on the Skin Microbiome in Patients With Moderate‐to‐Severe Atopic Dermatitis

Allergy, EarlyView.
Atopic dermatitis (AD) is characterized by microbial dysbiosis. This study aimed to evaluate the effects of abrocitinib, a JAK1‐selective inhibitor, on the skin microbiome and its potential associations with clinical outcomes in patients with AD. Abrocitinib treatment was associated with increased skin microbial diversity and decreased Staphylococcus ...
Madeline Kim, Ester Del Duca, Joel Correa Da Rosa, Juliana Pulsinelli, Yeriel Estrada, Dan Xu, Gary Chan, Allshine Chen, Erman Güler, Karen Page, Emma Guttman‐Yassky   +10 more
wiley   +1 more source

Molecular Design of Artificial Nucleases and Ribonucleases

Journal of Japan Oil Chemists' Society, 1994
KOMIYAMA, Makoto, YASHIRO, Morio
openaire   +1 more source

The DNA/RNA Helicase SETX Maintains R‐Loop Homeostasis to Promote Chemoresistance in Ovarian Cancer

Cancer Science, EarlyView.
SETX maintains R‐loop homeostasis by resolving excessive R‐loops, thereby promoting tumor initiation and chemoresistance. Deficiency of SETX leads to accumulation of unsolved pathological R‐loops, resulting in irreparable DNA damage and ultimately leading to tumor suppression and chemosensitivity.
Zi‐Wei Hu, Tu‐Nan Xu, Zi‐Ying Wang, Xin Zheng, Duan‐Yong Feng, Xiao‐Min Wang, Er‐Suo Jin, Ming Ren, Xiao‐Min Yang, Xian‐Chao Zhang, Xuan Che, Wei‐Wei Pan, Zha‐Jun Zhan, Shu‐Qun Cheng   +13 more
wiley   +1 more source

From biology to biotechnology: Host‐regulation factors from parasitoid wasps are a source of bioactive molecules with translational potential

Insect Molecular Biology, EarlyView.
Parasitoid wasps deploy maternal and embryonic factors to reprogramme host physiology. Venom, calyx fluid, polydnaviruses, teratocytes and larval secretions act in a coordinated, compartmentalised manner. Host‐regulation factors are promising sources of insecticidal, antimicrobial and bioinspired translational molecules.
Ciro Pedro G. Pinto, Andrew A. Walker, Glenn F. King   +2 more
wiley   +1 more source

A CRISPR‐Based Rapid Detection Assay for Crayfish Plague (Aphanomyces astaci) From Environmental Samples

Journal of Fish Diseases, EarlyView.
ABSTRACT Crayfish plague, caused by Aphanomyces astaci (Aa), is an infectious disease invasive in Europe, where its rapid spread has resulted in sharp declines of native crayfish species. Monitoring currently relies on a highly sensitive, but costly and time‐consuming qPCR approach.
Christopher Heine, Amadeus Plewnia, David Strand, Simran Gupta, Henrik Krehenwinkel, Gus R. McFarlane   +5 more
wiley   +1 more source

α‐1,3‐Glucan Is Required for Cell Wall Integrity and Full Virulence of Colletotrichum graminicola, but Not for Evasion of PAMP‐Triggered Immunity

Molecular Microbiology, EarlyView.
Abbreviated Summary The role of the major fungal cell wall polymer α‐1,3‐glucan in plant infection is poorly understood. Deletion mutants of the maize anthracnose fungus Colletotrichum graminicola lacking all three α‐1,3‐glucan synthase genes differentiated severely distorted biotrophic hyphae in planta, and virulence was strongly reduced.
Iris Gase, Lala Aliyeva‐Schnorr, Michael Melzer, Maria Ott, Julia Haufe, Matthias Menzel, Timo Engelsdorf, Christiane Rohrbach, Alan de Oliveira Silva, Lars M. Voll, Alexander S. Mickel, Maximilian Groß, Mamoru Wakayama, Holger B. Deising   +13 more
wiley   +1 more source