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Aryl Hydrocarbon Receptor in Health and Disease [PDF]
MedCommThe aryl hydrocarbon receptor (AhR) functions as a ligand‐dependent transcription factor, serving as a pivotal environmental sensor that significantly influences both physiological and pathological processes.
Haonan Li +11 more
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NEW TRENDS IN ARYL HYDROCARBON RECEPTOR BIOLOGY [PDF]
Frontiers in Cell and Developmental Biology, 2016 Traditionally considered as a critical intermediate in the toxic and carcinogenic response to dioxin (2,3,7,8-tetrachlorodibenzo-p-dioxin, TCDD), the Aryl hydrocarbon/Dioxin receptor (AhR) has proven to be also an important regulator of cell physiology ...
Pedro M. Fernández-Salguero +1 more
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Enantiospecific effects of ketoconazole on aryl hydrocarbon receptor. [PDF]
PLoS ONE, 2014 Azole antifungal ketoconazole (KET) was demonstrated to activate aryl hydrocarbon receptor (AhR). Since clinically used KET is a racemic mixture of two cis-enantiomers (2R,4S)-(+)-KET and (2S,4R)-(-)-KET, we examined the effects of KET enantiomers on AhR
Aneta Novotna +8 more
doaj +3 more sources
Aryl Hydrocarbon Receptor and Stem Cells
Stem Cells International, 2017 Thomas A. Gasiewicz +2 more
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The Kynurenine Pathway, Aryl Hydrocarbon Receptor, and Alzheimer’s Disease [PDF]
Brain SciencesAlzheimer’s disease (AD) is the leading cause of dementia, mainly affecting elderly individuals. AD is characterized by β-amyloid plaques, abnormal tau tangles, neuronal loss, and metabolic disruptions. Recent studies have revealed the involvement of the
Enoc Mariano Cortés Malagón +3 more
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环境与职业医学, 2023 BackgroundDue to the limited availability of established research models, very few studies addressed the health effects and underlying mechanisms following exposure to diesel exhaust during the initiation of pulmonary respiration.
Hao NI +4 more
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Biochemistry and Biophysics Reports, 2022 Indigo naturalis, a herbal medicine purified from indigo-containing plants, such as Strobilanthes cusia, Isatis tinctoria, and Polygonum tinctorium, has been reported to be useful in the treatment of ulcerative colitis by activating the aryl hydrocarbon ...
Taka Asari +14 more
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Aryl hydrocarbon receptor deficiency enhances astrocyte sensitivity to LPS-induced inflammation. [PDF]
Front Cell NeurosciOjo E, Tischkau SA.
europepmc +3 more sources
Vitiligo patients show significant up-regulation of aryl hydrocarbon receptor transcription factor [PDF]
Anais Brasileiros de Dermatologia, 2018 : IL-22 has been implicated in the pathogenesis of vitiligo. However, the role of aryl hydrocarbon receptor transcription factor that acts as a master regulator of IL-22-producing Th22 cells is not fully understood.
Farinaze Behfarjam, Zohreh Jadali
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Журнал инфектологии, 2023 Recently, more attention has been paid to the role of indolamine-2,3-dioxygenase and aryl hydrocarbon receptor in maintaining a balance between immune reactivity and tolerance in various infectious diseases.
A. E. Taraskina +4 more
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