Results 121 to 130 of about 36,412 (300)

Protective Effects of Maclurin against Benzo[a]pyrene via Aryl Hydrocarbon Receptor and Nuclear Factor Erythroid 2-Related Factor 2 Targeting [PDF]

, 2021
Jangsoon Kim, See‐Hyoung Park, Seyoung Yang, Sae Woong Oh, Kitae Kwon, Se Jin Park, Eunbi Yu, Hyeyoun Kim, Jung Yoen Park, Seoyoung Choi, Seoyeon Yang, Minkyung Song, Jae Youl Cho, Jongsung Lee   +13 more
openalex   +1 more source

Tryptophan‐Derived Microbial Metabolite Indole‐3‐Acetic Acid Ameliorates Periodontitis Through AhR/CYP1A1‐Mediated Macrophage Polarisation

Journal of Clinical Periodontology, EarlyView.
ABSTRACT Aim To investigate the association between tryptophan‐derived microbial metabolites and periodontitis, and to assess whether the differential tryptophan metabolite indole‐3‐acetic acid (IAA) could ameliorate periodontitis and elucidate its potential mechanism.
Shuyu Cheng, Shiyuan Song, Wen Zhang, Dan Qiao, Min Wang, Zhifeng Wang, Jiajie Pu, Wenrong Yang, Fuhua Yan, Yangheng Zhang   +9 more
wiley   +1 more source

Role of aryl hydrocarbon receptor (AHR) in overall retinoid metabolism: Response comparisons to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) exposure between wild-type and AHR knockout mice

, 2021
Javier Esteban, Ismael Sánchez-Pérez, Gerd Hamscher, Hanna M. Miettinen, Merja Korkalainen, Matti Viluksela, Raimo Pohjanvirta, Helen Håkansson   +7 more
openalex   +1 more source

Epigenetic Regulation in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
The aim of this narrative literature review was to identify epigenetic marks associated with periodontitis and to place them in a biological context. The literature was reviewed based on pre‐defined criteria. Cell type specific chromatin and mRNA modifications were included.
Henrik Dommisch, Arne Sönke Schäfer, Denica Kuzmanova, Dominique S. Michaud   +3 more
wiley   +1 more source

Aryl Hydrocarbon Receptor Signaling Prevents Activation of Hepatic Stellate Cells and Liver Fibrogenesis in Mice

, 2019
Jiong Yan, Hung‐Chun Tung, Sihan Li, Yongdong Niu, Wojciech G. Garbacz, Peipei Lu, Yuhan Bi, Yanping Li, Jinhan He, Meishu Xu, Songrong Ren, Satdarshan P. Monga, Robert F. Schwabe, Da Yang, Wen Xie   +14 more
openalex   +2 more sources

A novel synthetic analogue of a constituent of Isodon excisus inhibits transcription of CYP1A1, -1A2 and -1B1 by preventing activation of the aryl hydrocarbon receptor [PDF]

, 2006
Paweł Sienkiewicz, Henry P. Ciolino, Benjamin J. Leslie, Paul J. Hergenrother, Keith W. Singletary, Grace Chao Yeh   +5 more
openalex   +1 more source

On the Nature of Improper Hydrogen Bonding in RCH2F and RCHF2 Motifs

Angewandte Chemie, Volume 138, Issue 2, 9 January 2026.
The nature of ‘improper’ hydrogen bonds is explored in FnC─H⋯X systems, such as RCF2H interaction with chloride and water. It is noted that increased fluorination decreases the positive charge density on H but increases it on C, thus these interactions are dominated by electrostatic attraction to C over H.
Bruno A. Piscelli, Michael Bühl, Rodrigo A. Cormanich, David O'Hagan   +3 more
wiley   +2 more sources

Exercise‐induced effects on atherogenesis and tryptophan catabolism via the kynurenine pathway in an HIV‐associated atherosclerosis mouse model

Experimental Physiology, EarlyView.
Abstract A mouse model of HIV‐associated atherosclerosis (Tg26+/−ApoE−/−) exhibited increased plaque area compared with the ApoE−/− mouse, linked to elevated indoleamine 2,3‐dioxygenase (IDO) activity. IDO catalyses the conversion of tryptophan (TRP) into kynurenine (KYN), measured by the KYN‐to‐TRP ratio.
Marcus V. S. Rangel, Mohammad Afaque Alam, Mohammad Islamuddin, Zheng Chen, Xuebin Qin, Juliana P. Borges   +5 more
wiley   +1 more source

Identification of new aryl hydrocarbon receptor (AhR) antagonists using a zebrafish model

, 2019
Jieun Jeong, Kun-Hee Kim, Dong‐Young Kim, C. Gopalakrishnan, Minhee Kim, Suvarna H. Pagire, Mahesh Dighe, Eun Young Choi, Su-Min Bak, Eun‐Young Kim, Myung‐Geun Shin, Seok‐Yong Choi, Jin Hee Ahn   +12 more
openalex   +1 more source

Targeting Tumor Dormancy and Recurrence: Molecular Mechanisms and Peptide Therapeutic Delivery

MedComm – Oncology, Volume 5, Issue 1, March 2026.
This review summarizes the molecular mechanisms that regulate tumor dormancy and its role in cancer recurrence, with emphasis on immune evasion, extracellular matrix remodeling, metabolic regulation and angiogenic switching. It further discusses emerging peptide–based therapeutic strategies aimed at detecting, modulating, and eliminating dormant tumor ...
Abdur Raheem Aleem, Atif Ali, Wajid Ali, Yuying Cheng, Zhibin Yan, Chaoyi Xia, Chenguang Liu, Caiyun Fu, Yiren Hu, Xi Wang   +9 more
wiley   +1 more source