Results 21 to 30 of about 36,412 (300)
eLife, 2020 Systemic metabolic reprogramming induced by infection exerts profound, pathogen-specific effects on infection outcome. Here, we detail the host immune and metabolic response during sickness and recovery in a mouse model of malaria.
Michelle M Lissner +7 more
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Oculomotor deficits in aryl hydrocarbon receptor null mouse. [PDF]
PLoS ONE, 2013 The Aryl hydrocarbon Receptor or AhR, a ligand-activated transcription factor, is known to mediate the toxic and carcinogenic effects of various environmental pollutants such as 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD). Recent studies in Caenorhabditis
Aline Chevallier +6 more
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Aryl hydrocarbon receptor and intestinal immunity [PDF]
Mucosal Immunology, 2018 Aryl hydrocarbon receptor (AhR) is a member of the basic helix-loop-helix-(bHLH) superfamily of transcription factors, which are associated with cellular responses to environmental stimuli, such as xenobiotics and oxygen levels. Unlike other members of bHLH, AhR is the only bHLH transcription factor that is known to be ligand activated.
Lamas, Bruno +2 more
openaire +3 more sources
The Aryl Hydrocarbon Receptor Pathway Defines the Time Frame for Restorative Neurogenesis
Cell Reports, 2018 Summary: Zebrafish have a high capacity to replace lost neurons after brain injury. New neurons involved in repair are generated by a specific set of glial cells, known as ependymoglial cells.
Rossella Di Giaimo +17 more
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Frontiers in Immunology, 2022 Rheumatoid arthritis (RA), the most common autoimmune disease, is characterized by symmetrical synovial inflammation of multiple joints with the infiltration of pro-inflammatory immune cells and increased cytokines (CKs) levels.
Xiaoyu Xi +15 more
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The Aryl Hydrocarbon Receptor and Tumor Immunity
Frontiers in Immunology, 2018 The aryl hydrocarbon receptor (AhR) is an important cytosolic, ligand-dependent transcription factor. Emerging evidence suggests the promoting role of the AhR in the initiation, promotion, progression, invasion, and metastasis of cancer cells. Studies on
Ping Xue +3 more
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Nature Communications, 2022 Eusocial honeybee is a versatile model for neurobiological research. Here, the authors established a link between honeybee gut Lactobacillus in bee learning and memory ability via indole derivatives that activate host’s aryl hydrocarbon receptor.
Zijing Zhang +5 more
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Maternal aryl hydrocarbon receptor activation protects newborns against necrotizing enterocolitis
Nature Communications, 2021 Necrotizing enterocolitis (NEC) is a disease of prematurity requiring Toll-like receptor 4 (TLR4) activation on the gut epithelium. Here the authors show that the aryl hydrocarbon receptor (AHR) mediates NEC pathogenesis via effects on TLR4, and that ...
Peng Lu +12 more
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Interaction between AhR and HIF-1 signaling pathways mediated by ARNT/HIF-1β
BMC Pharmacology and Toxicology, 2022 Background The main causes of lung cancer are smoking, environmental pollution and genetic susceptibility. It is an indisputable fact that PAHs are related to lung cancer, and benzo(a) pyrene is a representative of PAHs.
Mengdi Zhang +10 more
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Microbiology Spectrum, 2021 The aryl hydrocarbon receptor (AHR) is a ligand-activated transcript factor that plays an important role in regulating immunity and cell differentiation. However, its role in cell-autonomous antiviral resistance has not been fully elucidated.
Jincheng Chen +11 more
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