Results 111 to 120 of about 11,887 (214)

Aryl hydrocarbon receptor activation mediates kidney disease and renal cell carcinoma. [PDF]

open access: yes, 2019
The aryl hydrocarbon receptor (AhR) is a well-known ligand-activated cytoplasmic transcription factor that contributes to cellular responses against environmental toxins and carcinogens.
Chen, Lin   +8 more
core   +1 more source

HMGCS2 is a key ketogenic enzyme potentially involved in type 1 diabetes with high cardiovascular risk. [PDF]

open access: yes, 2017
Diabetes increases the risk of Cardio-vascular disease (CVD). CVD is more prevalent in type 2 diabetes (T2D) than type 1 diabetes (T1D), but the mortality risk is higher in T1D than in T2D. The pathophysiology of CVD in T1D is poorly defined.
Addya, Sankar   +6 more
core   +2 more sources

Induction of the rat hepatic aryl hydrocarbon receptor nuclear translocator by glucocorticoids

open access: yesThe FASEB Journal, 2013
The aryl hydrocarbon receptor nuclear translocator (ARNT) is a shared partner between the hypoxia signaling pathway and the dioxin‐responsive aryl hydrocarbon receptor signaling pathway. Dexamethasone (DEX), a synthetic glucocorticoid known to activate both the glucocorticoid receptor (GR) and the pregnane X receptor (PXR), was ...
Sarah R Hunter, David S Riddick
openaire   +1 more source

Xenobiotic-induced activation of human aryl hydrocarbon receptor target genes in Drosophila is mediated by the epigenetic chromatin modifiers [PDF]

open access: yes, 2017
Aryl hydrocarbon receptor (AHR) is the key transcription factor that controls animal development and various adaptive processes. The AHR\u27s target genes are involved in biodegradation of endogenous and exogenous toxins, regulation of immune response ...
Akishina, Angelina A.   +11 more
core   +1 more source

Role of ARNT2 in Cancer with Specific Emphasis on Oral Squamous Cell Carcinoma: A Bibliometric Review [PDF]

open access: yesJournal of Clinical and Diagnostic Research
Introduction: Oral Squamous Cell Carcinoma (OSCC) remains a significant public health issue worldwide, given its rising incidence and unfavourable survival rates, even with treatment advances.
Ravi Aravindhan   +4 more
doaj   +1 more source

Bacopa monnieri (Brahmi) induced Autophagy Inhibit Benzo[a]pyrene mediated cytotoxicity [PDF]

open access: yes, 2014
Particulate matters like PAHs (Polycyclic Aromatic Hydrocarbons) are one of the most common and dangerous air pollutants which severely affect the organisms.
Nayak, Aditi
core  

Silencing of hypoxia-inducible factor-1β induces anti-tumor effects in hepatoma cell lines under tumor hypoxia.

open access: yesPLoS ONE, 2014
Dimerization of hypoxia-inducible factor-1 beta (HIF-1β) [aryl hydrocarbon receptor nuclear translocator (ARNT)] with HIF-1α is involved in various aspects of cancer biology, including proliferation and survival under hypoxic conditions.
Sung Hoon Choi   +10 more
doaj   +1 more source

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