Aryl hydrocarbon receptor overexpression in miniaturized follicles in female pattern hair loss [PDF]
Anais Brasileiros de Dermatologia, 2017 The etiopathogenesis of female pattern hair loss is still poorly understood. In addition to genetic and hormonal elements, environmental factors could be involved.
Paulo Müller Ramos +5 more
doaj +2 more sources
Regulation of host immune responses by Lactobacillus through aryl hydrocarbon receptors
Medicine in Microecology, 2023 The aryl hydrocarbon receptor (AhR) is a ligand-dependent transcription factor that serves as a key environmental sensor and mechanistic regulator of both the epithelial barrier and systemic immunity. Exogenous ligands (aromatic compounds such as dioxins)
Zhipeng Huang, Liwei Xie, Liping Huang
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AhR, PXR and CAR: From Xenobiotic Receptors to Metabolic Sensors
Cells, 2023 Traditionally, xenobiotic receptors are known for their role in chemical sensing and detoxification, as receptor activation regulates the expression of various key enzymes and receptors.
Leonida Rakateli +2 more
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Aryl Hydrocarbon Receptors in Indole Derivative Treated Mice: Neuropharmacological Perspectives
Acta Medica Bulgarica, 2021 Aim/objective. When applied in pharmacological doses, the indole derivative melatonin exhibits neuroactive and neuroprotective effects. Indoles and their metabolites, such as kynurenine, are ligands of aryl hydrocarbon receptors (AhR).
Andreeva-Gateva P. +7 more
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Six Decades of Dopamine Hypothesis: Is Aryl Hydrocarbon Receptor the New D2?
Reports, 2023 In 1957, Arvid Carlsson discovered that dopamine, at the time believed to be nothing more than a norepinephrine precursor, was a brain neurotransmitter in and of itself.
Adonis Sfera
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Potential roles of gut microbial tryptophan metabolites in the complex pathogenesis of acne vulgaris
Frontiers in Microbiology, 2022 Acne vulgaris is a chronic inflammatory skin disease in which the influence of gut microbiota has been implicated but without clarification of mechanisms. Gut microbiota may exert such an influence via metabolites, particularly those of tryptophan.
Yukun Huang +6 more
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High Serum-Induced AhRL Is Associated with Prevalent Metabolic Syndrome and Future Impairment of Glucose Tolerance in the Elderly [PDF]
Endocrinology and Metabolism, 2021 Background High circulating levels of dioxins and dioxin-like chemicals, acting via the aryl hydrocarbon receptor (AhR), have previously been linked to diabetes.
Youngmi Kim Pak +6 more
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Antioxidants for Healthy Skin: The Emerging Role of Aryl Hydrocarbon Receptors and Nuclear Factor-Erythroid 2-Related Factor-2. [PDF]
Nutrients, 2017 Furue M +7 more
europepmc +2 more sources
Atypical functions of xenobiotic receptors in lipid and glucose metabolism
Medical Review, 2022 Xenobiotic receptors are traditionally defined as xenobiotic chemical-sensing receptors, the activation of which transcriptionally regulates the expression of enzymes and transporters involved in the metabolism and disposition of xenobiotics.
Wang Jingyuan, Lu Peipei, Xie Wen
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The aryl hydrocarbon receptor system [PDF]
dmdi, 2012 Abstract The aryl hydrocarbon receptor (AhR) recognizes a large number of xenobiotics, such as polyaromatic hydrocarbons (PAHs) and dioxins, and it activates several metabolic and detoxification pathways. Recent evidence suggests that this receptor also has important endogenous functions subsequent to activation by natural dietary ...
Barouki, Robert +3 more
openaire +2 more sources