Arylamine N-acetyltransferase 2 Polymorphisms and the Risk of Endometriosis. [PDF]
Avicenna J Med Biotechnol, 2018 Barra F +3 more
europepmc +4 more sources
Arylamine N-Acetyltransferase in Mycobacteria [PDF]
, 2018 Arylamine N-acetyltransferase (NAT) was first identified in humans for its role in metabolising the anti-tubercular drug isoniazid. Later functional NAT proteins were identified in bacteria including Mycobacterium tuberculosis where they were found to N ...
Sanjib Bhakta +3 more
core +1 more source
NAT1 (N-acetyltransferase 1 (arylamine N-acetyltransferase)) [PDF]
Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2011 Review on NAT1 (N-acetyltransferase 1 (arylamine N-acetyltransferase)), with data on DNA, on the protein encoded, and where the gene is implicated.
Ruiz, JD +3 more
openaire +2 more sources
Determination of Human NAT2 Acetylator Genotype by Oligonucleotide Ligation Assay
BioTechniques, 1997 The oligonucleotide ligation assay (OLA) was adapted to the genotyping of the N-arylamine-acetyltransferase (NAT2) gene. This assay allows the use of 96-well microplates and robotic workstations for high sample throughput.
Jeannette Bigler +2 more
doaj +1 more source
Annals of Hepatology, 2020 Introduction and objective: Hepatotoxicity during tuberculosis (TB) treatment is frequent and may be related to the Arylamine N-Acetyltransferase (NAT2) acetylator profile, in which allele frequencies differ according to the population.
Carolline Araujo-Mariz +8 more
doaj +1 more source
Small Molecule Colorimetric Probes for Specific Detection of Human Arylamine N-Acetyltransferase 1, a Potential Breast Cancer Biomarker [PDF]
, 2016 Small Molecule Colorimetric Probes for Specific Detection of Human Arylamine N-Acetyltransferase 1, a Potential Breast Cancer ...
Ai M. Fletcher (1310784) +8 more
core +1 more source
Microbial Cell Factories, 2020 Background 2-Acetamidophenol (AAP) is an aromatic compound with the potential for antifungal, anti-inflammatory, antitumor, anti-platelet, and anti-arthritic activities.
Shuqi Guo +4 more
doaj +1 more source
A novel color change mechanism for breast cancer biomarker detection: naphthoquinones as specific ligands of human arylamine N-acetyltransferase 1. [PDF]
PLoS ONE, 2013 Human arylamine N-acetyltransferase 1 (hNAT1) has become an attractive potential biomarker for estrogen-receptor-positive breast cancers. We describe here the mechanism of action of a selective non-covalent colorimetric biosensor for the recognition of ...
Nicola Laurieri +11 more
doaj +1 more source
Identification and Characterization of Two Isozymic Forms of Arylamine N-Acetyltransferase in Syrian Hamster Skin [PDF]
, 1993 Arylamine N-acetyltransferase (EC 2.3.1.5) activity was examined using skin from Syrian hamster. Two isozymes of arylamine N-acetyltransferase, designated NAT-1 and NAT-2, were detected on anion-exchange high-performance liquid chromatography analysis ...
Namboodiri, M A A +5 more
core +1 more source
New oxadiazole derivatives of isonicotinohydrazide in the search for antimicrobial agents: Synthesis and in vitro evaluation [PDF]
Journal of the Serbian Chemical Society, 2012 Structural modification of the front line antitubercular drug isoniazid provide a lipophilic adaptations of the drug in which hydrazide moiety of isoniazid is replaced by 1,3,4-oxadiazole heterocycles to eliminate in-vivo acetylation by arylamine N ...
Malhotra Manav +3 more
doaj +1 more source