Results 61 to 70 of about 2,480 (127)

As1411-modified liposomes to enhance drug utilization and augment the anti-tumor efficacy

Cancer Nanotechnology
Background The utilization of liposomes in drug delivery has garnered significant attention due to their efficient drug loading capacity and excellent biocompatibility, rendering them a promising platform for tumor therapy.
Danhuan Zhang, Lingyun Chen, Yang Zhao, Hao Ni, Qiuying Quan, Jun Ma, Lingchuan Guo   +6 more
doaj   +1 more source

A pH-Sensitive I-Motif Aptamer Probe for Dual Targeting and Imaging of Pancreatic Cancer Cells via Nucleolin Interactions

Journal of Bio-X Research
This study investigates the targeted imaging and tumor inhibition effects of a “signal-off” imaging-based activatable aptamer probe (I-AAP) for pancreatic cancer.
Quwen Li, Qingquan Chen, Juan Tang, Qicai Liu, Feng Gao   +4 more
doaj   +1 more source

ISEV2026 Abstract Book

Journal of Extracellular Vesicles, Volume 15, Issue S1, June 2026.
wiley   +1 more source

Preparation of AS1411 Aptamer Modified Mn-MoS2 QDs for Targeted MR Imaging and Fluorescence Labelling of Renal Cell Carcinoma

International Journal of Nanomedicine, 2019
Shaohui Zheng,1–3,* Min Zhang,2,* Hongyan Bai,2 Meijuan He,2 Lina Dong,2 Lulu Cai,2 Mingming Zhao,2 Qi Wang,2 Kai Xu,1–3 Jingjing Li1–3 1Department of Radiology, Affiliated Hospital of Xuzhou Medical University, Xuzhou 221006, People ...
Zheng S, Zhang M, Bai H, He M, Dong L, Cai L, Zhao M, Wang Q, Xu K, Li J   +9 more
doaj  

Novel nanosized AS1411–chitosan–BODIPY conjugate for molecular fluorescent imaging

International Journal of Nanomedicine, 2019
Setareh Taki,1 Mehdi Shafiee Ardestani21Department of Radiopharmacy, International Campus, School of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran; 2Department of Radiopharmacy, Faculty of Pharmacy, Tehran University of Medical Sciences ...
Taki S, Ardestani MS
doaj  

Targeting glutamine synthetase with AS1411-modified exosome-liposome hybrid nanoparticles for inhibition of choroidal neovascularization

Journal of Nanobiotechnology
Choroidal neovascularization (CNV) is a leading cause of visual impairment in wet age-related macular degeneration (wAMD). Recent investigations have validated the potential of reducing glutamine synthetase (GS) to inhibit neovascularization formation ...
Miaomiao Zhang, Xinyue Lu, Lifu Luo, Jinqiu Dou, Jingbo Zhang, Ge Li, Li Zhao, Fengying Sun   +7 more
doaj   +1 more source

Preparation of Bmi-1-siRNA Lipid Nanoparticles and Effects in Gastric Cancer

Nano Biomedicine and Engineering
Malignant tumors remain a serious threat to human health and life and are a major public health problem globally. Herein, we designed and synthesized a novel nucleic acid nanomedicine AS1411-siRNA-LNPs (As@LNPs).
Hongzhang Yan, Hong Shen, Jinrong SiTu, Yingying Yang, Lingle Zhang, Kai Yang   +5 more
doaj   +1 more source

Advancing targeted combination chemotherapy in triple negative breast cancer: nucleolin aptamer-mediated controlled drug release

Journal of Translational Medicine
Background Triple-negative breast cancer (TNBC) is a recurrent, heterogeneous, and invasive form of breast cancer. The treatment of TNBC patients with paclitaxel and fluorouracil in a sequential manner has shown promising outcomes.
Yuan Ma, Duoli Xie, Zefeng Chen, Xinyang Shen, Xiaoqiu Wu, Feng Ding, Shijian Ding, Yufei Pan, Fangfei Li, Aiping Lu, Ge Zhang   +10 more
doaj   +1 more source

[Ultrasound-synergized targeted nanoparticles suppress proliferation, migration and invasion of hypoxic lung cancer cells <i>in vitro</i>]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Dong J, Guo J, Li D, DU Y.
europepmc   +1 more source

Synthetic aptamer mechanoreceptors enable cell-specific force sensing and temporal control via DNA circuits. [PDF]

Nat Commun
Xu T, Sethi S, Drees C, Walther A.
europepmc   +1 more source